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pro vyhledávání: '"Preclinical research"'
Autor:
Natalie D. Keirstead, Garvin Warner, Carole E. Harbison, Brenda Carito, Akshay Vaishnaw, Jessica E. Sutherland, Victoria K. Perry, Maja M. Janas
Publikováno v:
Toxicologic Pathology
Short interfering RNAs (siRNAs) and antisense oligonucleotides (ASOs) are the most clinically advanced oligonucleotide-based platforms. A number of N-acetylgalactosamine (GalNAc)-conjugated siRNAs (GalNAc-siRNAs), also referred to as RNA interference
Autor:
Michael W. Leach
Publikováno v:
Toxicologic Pathology. 41:128-136
With the advances in cell culture methodologies and molecular biology that have occurred over the past several decades, biologics have become as common as small molecules within the portfolios of the pharmaceutical industry. Toxicologic pathologists