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Autor:
Anna Urbańska, Bartosz Szetela, Władysław Łojewski, Monika Bociąga-Jasik, Miłosz Parczewski, Kaja Scheibe, Paweł Jakubowski, Aleksandra Szymczak, Maria Hlebowicz, Aleksandra Raczyńska
Publikováno v:
Antiviral Therapy. 26:69-78
Introduction Doravirine (DOR) is a novel non-nucleoside reverse transcriptase inhibitor (NNRTI) that retains activity against common NNRTI resistance mutations. In this study, we aimed to investigate the prevalence of DOR resistance mutations compare
Publikováno v:
Journal of Oncology Pharmacy Practice. 27:954-961
Colorectal cancer is one of the commonest malignancies worldwide. The estimated lifetime risk of the disease is about 5% with an incidence of one million new cases and 600,000 deaths worldwide every year. It is estimated that in 2019, approximately 1
Autor:
David E. Nix, Kathleen C. Blomquist
Publikováno v:
Annals of Pharmacotherapy. 55:1010-1024
Objective: This article critically evaluates common Pseudomonas aeruginosa resistance mechanisms and the properties newer β-lactam antimicrobials possess to evade these mechanisms. Data Sources: An extensive PubMed, Google Scholar, and ClinicalTrial
Publikováno v:
Annals of Pharmacotherapy. 54:1252-1259
Objective: To review data on efficacy and safety of dolutegravir (DTG) and lamivudine (3TC) in treatment-naïve adults with HIV-1 infection. Data Sources: Phase III clinical trials and review articles were identified through PubMed (1996 to March 202
Publikováno v:
Annals of Pharmacotherapy. 54:197-204
Background: Data are limited regarding the preferred antibiotics for treatment of acute pulmonary exacerbations (APEs) of cystic fibrosis (CF), when methicillin-resistant Staphylococcus aureus (MRSA) is suspected. Objective: To compare the rate of re
Publikováno v:
Journal of Pharmacology and Pharmacotherapeutics. 10:85-92
Objective: To evaluate the effects of curcumin (CUM) against Nicotine (NIC) induced damage to the hippocampal cortex of rats. Materials and Methods: In this study, 48 Wistar male rats were randomly assigned to eight groups: normal group, NIC group (0
Publikováno v:
Journal of Pharmacology and Pharmacotherapeutics. 10:93-99
Objective: To evaluate the anticonvulsant and antioxidant actions of diltiazem, nimodipine, and flunarizine in the Wistar albino rats using the maximum electroshock-induced seizure (MES) model. Materials and Methods: Thirty inbred Wistar rats were di
Autor:
Claudio D Ávila-Andrade, Vega Iranzo, Alberto Jacobo Cunquero-Tomás, Karla Javier, Javier Milara, Carlos Camps
Publikováno v:
Journal of Oncology Pharmacy Practice. 26:492-495
Introduction Glucose 6-phosphate dehydrogenase (G6PD) is a basic antioxidant pathway for erythrocytes, being its deficiency the most common gene mutation worldwide. As breast cancer is one of the most frequent tumors, many of these patients may prese
Publikováno v:
Annals of Pharmacotherapy. 53:1124-1135
Objective: To review the pharmacology, pharmacokinetics, efficacy, safety, and place in therapy of eravacycline, a novel fluorocycline antibiotic from the tetracycline family. Data Sources: A PubMed search was conducted for data between 1946 and Marc
Publikováno v:
International Journal of STD & AIDS. 30:710-714
Organ transplantation among people living with human immunodeficiency virus (PLHIV) is increasing. Guidelines recommend any changes in antiretroviral therapy (ART) prior to transplantation, but there are limited data regarding ART changes post transp