Zobrazeno 1 - 10
of 343
pro vyhledávání: ''
Autor:
Jinghuan Fang, Michael Chopp, Li He, Li Zhang, Zheng Gang Zhang, Zhongwu Liu, William A. Golembieski, Fengjie Wang, Hongqi Xin
Publikováno v:
J Cereb Blood Flow Metab
Plasminogen is involved in the process of angiogenesis; however, the underlying mechanism is unclear. Here, we investigated the potential contribution of plasmin/plasminogen in mediating angiogenesis and thereby contributing to functional recovery po
Autor:
Ziyun Jiang, Junfang Zuo
Publikováno v:
Vascular Medicine. 25:295-301
Preeclampsia is a life-threatening multiorgan systemic disease with manifestations including gestational hypertension, oxidative stress, and vascular dysfunction. We aimed to evaluate the therapeutic effects of melatonin on an L-NAME (NLG-nitro-l-arg
Publikováno v:
Journal of Cardiovascular Pharmacology and Therapeutics. 25:354-363
Background:Insulin resistance (IR) is a well-known risk factor for cardiovascular complications. This study aimed to investigate the effect of a dietary model of IR in mice on cardiac remodeling, cardiac β-arrestin2 signaling, and the protective eff
Autor:
Patricia Bonazzola, Germán A. Colareda, Alicia E. Consolini, Matías Bayley, María Inés Ragone
Publikováno v:
Journal of Cardiovascular Pharmacology and Therapeutics. 25:72-85
Hypothyroidism is considered a cardiac risk factor, but there is controversial evidence about its effects on coronary disease. The aim of this work was to evaluate the influence of hypothyroidism in rat hearts exposed to 2 degrees of stunning due to
Autor:
María Lacalle-Aurioles, Lianne J. Trigiani, Frédéric Lesage, John G. Sled, Darren J. Fernandes, Clotilde Lecrux, Amy Hynes, Shoshana Spring, Markus Schwaninger, Edith Hamel, Miled Bourourou
Publikováno v:
J Cereb Blood Flow Metab
A vascular insult occurring early in disease onset may initiate cognitive decline leading to dementia, while pharmacological and lifestyle interventions can prevent this progression. Mice with a selective, tamoxifen-inducible deletion of NF-κB essen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d524596f3003781967ae003aa6fe150
https://europepmc.org/articles/PMC8721775/
https://europepmc.org/articles/PMC8721775/
Autor:
Walter Raasch, Lukas Huber, Olga Will, Mikolaj Ogrodnik, Diana Jurk, Gianna Huber, Urte Matschl, Markus Schwaninger, Ines Stölting, Jan-Bernd Hövener, Jan Wenzel, Eva Peschke
Publikováno v:
J Cereb Blood Flow Metab
Angiotensin II receptor blockers (telmisartan) prevent rodents from diet-induced obesity and improve their metabolic status. Hyperglycemia and obesity are associated with reduced cerebral blood flow and neurovascular uncoupling which may lead to beha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ab5b34c048e32b3ad503769d6f9af53
https://europepmc.org/articles/PMC8393307/
https://europepmc.org/articles/PMC8393307/
Autor:
Ge Li, Yue Lan, Cheng Wu, Xiao-fei He, Yu Zhang, Yi-xuan Zeng, Guang-qing Xu, Fengyin Liang, Yukun Feng, Zhong Pei
Publikováno v:
J Cereb Blood Flow Metab
Using a photothrombotic mouse model of single stroke, we show that a single stroke onset increases the nuclear factor-κB (NF-κB), NLR family CARD domain containing protein 4 (NLRC4), and absent in melanoma 2 (AIM2) inflammasomes, as well as the mRN
Autor:
María Luna-Luna, Victoria López-Olmos, Cristobal Flores-Castillo, José Manuel Fragoso, Alberto Aranda-Fraustro, Gilberto Vargas-Alarcón, Elizabeth Carreón-Torres, Andrea Mondragón-García, Oscar Pérez-Méndez
Publikováno v:
Journal of Cardiovascular Pharmacology and Therapeutics. 24:559-566
Statins may precipitate the onset of type 2 diabetes (T2D) in high-risk patients. In contrast, only the subset of individuals with insulin resistance and/or diabetes receives cardiovascular benefits with fibrates. In this context, previous observatio
Publikováno v:
Diabetes and Vascular Disease Research. 15:567-570
Objective: Stroke is a severe complication of type 2 diabetes mellitus. Glucagon-like peptide-1 receptor agonists have been shown to have a neuroprotective effect in experimental diabetes. The aim of this study was to determine if their neuroprotecti
Publikováno v:
Journal of Cardiovascular Pharmacology and Therapeutics. 23:344-349
Sclerostin (Scl) is implicated in vascular calcification and angiogenesis and localizes within vasculature. Its molecule incorporates a heparin-binding site that implies also binding to endothelial glycocalyx. We preliminary tested whether intravenou