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Publikováno v:
Annals of Pharmacotherapy. 56:412-421
Background: Dolutegravir (DTG) plus lamivudine (2-DR) is suggested as an initial and switch option in HIV-1 treatment. Objective: To analyze the effectiveness, durability, and safety of 2-DR compared with DTG plus abacavir/lamivudine (3-DR). Methods:
Publikováno v:
Hospital Pharmacy. 57:345-348
A 38-years-old female with an aortic valve replacement presented to an outside hospital (OSH) with fevers and malaise. Blood cultures revealed VRE which was resistant to linezolid, resistant to ampicillin, non-susceptible to daptomycin (MIC of 8 mcg/
Autor:
Reynolds, Gavin
Publikováno v:
Journal of Psychopharmacology. 35:1030-1036
Guidelines for the treatment of schizophrenia limit the use of antipsychotic agents to clinically-established maximum doses. This acknowledges both the absence of additional efficacy of dopamine D2 receptor antagonists above a receptor occupancy thre
Publikováno v:
European Journal of Ophthalmology. 32:1627-1635
Purpose: To compare the efficacy of intravitreal (IV) ranibizumab (IVR) injection with IV dexamethasone implant (IVDEX) in treatment naive diabetic macular edema (DME) patients with inflammatory component. Materials and methods: Treatment naive DME e
Publikováno v:
J Psychopharmacol
Background: Choline supplementation (+Ch) improves cognitive function in impaired animals and humans. Chemotherapy-related cognitive deficits (CRCDs) occur in cancer patients, and these deficits persist following treatment, adversely impacting qualit
Publikováno v:
Statistical Methods in Medical Research. 30:1782-1799
Modern causal mediation theory has formalized several types of indirect and direct effects of treatment on outcomes regarding specific mediator variables. We reviewed and unified distinct approaches to estimate the “interventional” direct and ind
Autor:
Paula Telles Freitas, Nuno Campos, Ana Rita Carreira, Joao Cardoso, nadine sousa marques, Filipe Moraes, Pedro Carreira, Tomás Loureiro
Publikováno v:
European Journal of Ophthalmology. 32:1596-1601
Purpose: To assess the impact of one intravitreal injection (IVT) of Triamcinolone Acetonide (TA) on intraocular pressure (IOP) and optic nerve structural parameters in patients treated for Diabetic Macular Edema (DME). Methods: This retrospective st
Autor:
İmran Aydoğdu, Hüseyin Sari, Semih Karaketir, Yavuz Uyar, Hasan Sami Bircan, Enis Ekincioglu, Yavuz Atar, Güler Berkiten, Şeyma Görçin Karaketir, Enes Ataç
Publikováno v:
Annals of Otology, Rhinology & Laryngology. 131:427-434
Objective: We aim to demonstrate the effect of an isotonic seawater spray containing chamomile liquid extract on symptoms and nasal mucociliary clearance in patients with allergic rhinitis by comparing it with other isotonic seawater nasal washing so
Autor:
Janet Rimmer, Larry Kalish, Raewyn Campbell, Jacqueline Ho, Raymond Sacks, William A. Sewell, Raquel Alvarado, Peter Earls, Richard J. Harvey, Sophie Walter
Publikováno v:
American Journal of Rhinology & Allergy. 36:72-80
Background Biologic therapies such as mepolizumab and benralizumab are currently utilised in the treatment of eosinophilic asthma, and are emerging in the management of eosinophilic chronic rhinosinusitis (eCRS). These biologics inhibit the interacti
Autor:
Anthony J. Perissinotti, Bernard L. Marini, Kristen Pettit, Dale L. Bixby, Patrick W. Burke, Lydia L. Benitez, Brian Bazzell
Publikováno v:
Journal of Oncology Pharmacy Practice. 28:1315-1325
Background Patients diagnosed with acute myeloid leukemia with a FLT3 mutation (FLT3+ AML) have historically had poor outcomes. While the addition of the FLT3 inhibitors to induction therapy has been shown to improve survival outcomes in FLT3+ AML, i