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Autor:
Bipin Adhikari, Sabita Thapa, Megha Raj Banjara, Komal Raj Rijal, Upendra Thapa Shrestha, Binod Dhungel, Prakash Ghimire, Anil Kumar Shah, Nabaraj Adhikari, Ishworiya Lamichhane
Publikováno v:
Chemotherapy. 66:199-209
Background: Klebsiella pneumoniae is one of the leading causes of nosocomial infections. Carbapenems are used as the last resort for the treatment of multidrug resistant Gram-negative bacterial infections. In recent years, resistance to these lifesav
Autor:
Evangelista Sagnelli, Caterina Sagnelli, Paola Vitiello, Antonello Sica, Giuseppe Argenziano, Massimo Ciccozzi, Renato Franco, Andrea Ronchi
Publikováno v:
Chemotherapy. 65:161-165
Eleven years ago, a 64-year-old Caucasian man had LNH Follicular 3a, IV A stage, FLIPI 2 as a prognostic index of follicular lymphoma. He received 8 cycles of RCHOP followed by rituximab maintenance, with complete remission. Due to a systemic recurre
Publikováno v:
Chemotherapy. 64:210-214
Background: Pegylated asparaginase may induce prolonged hypertriglyceridemia. To date, there is no standard management of this complication. Here, we present a case report of pegylated asparaginase-induced hypertriglyceridemia and hepatotoxicity succ
Publikováno v:
Chemotherapy. 63:330-337
Due to increasing bacterial resistance and poor availability of new antibiotics, physicians need to use old, still active antibiotics more frequently. In this study, we focused on clofoctol and aimed to verify the emergence of clofoctol resistance
Autor:
Onikepe A. Folarin, Ismaila Watila, Temitope Aderoyeje, Bayo Fatunmbi, P. U. Agomo, Adejumoke I. Ayede, Chimere Agomo, Stephen Oguche, Christian T. Happi, Henrietta U. Okafor, Grace O. Gbotosho, A. Sowunmi, Kazeem Akano, William N. Ogala, Martin M Meremikwu, Godwin Ntadom, Elsie Adowoye
Publikováno v:
Chemotherapy. 62:231-238
Background: In severe malaria, intravenous artesunate may cause delayed haemolytic anaemia but there has been little evaluation of the propensity of oral artemisinin-based combination treatments (ACTs) to cause late-appearing anaemia. Methods: The fr
Autor:
Tomonobu Koizumi, Daisuke Gomi, Keiko Mamiya, Nodoka Sekiguchi, Hirohide Matsushita, Akiyuki Sakamoto, Toshirou Fukushima, Takashi Kobayashi, Shigeru Sasaki, Aika Tanaka
Publikováno v:
Chemotherapy. 62:225-230
Background and Aims: Several studies have indicated that cisplatin (cis-diamminedichloroplatinum II; CDDP) causes urinary excretion of L-carnitine (LC). However, the underlying cofactors affecting the increased urinary excretion remain unclear. The p
Autor:
Chanida Vinayanuwat, Pattama Angspatt, Piyada Sitthideatphaiboon, Nattaya Poovoravan, Tanchanok Ratanajarusiri, Virote Sriuranpong, Suebpong Tanasanvimon, Wilai Thawinwisan, Napa Parinyanitikul
Publikováno v:
Chemotherapy. 62:134-139
Purpose: To compare incidences of hypersensitivity reaction (HSR) between original and generic taxanes including paclitaxel and docetaxel. Methods: We conducted a prospective study enrolling all patients receiving taxanes at King Chulalongkorn Memori
Autor:
Hideo Kato, Hazuki Nakai, Hiroshige Mikamo, Jun Hirai, Hiroyuki Suematsu, Mao Hagihara, Yuka Yamagishi, Daisuke Sakanashi, Naoya Nishiyama, Yusuke Koizumi
Publikováno v:
Chemotherapy. 62:105-110
Background: Reports of Pseudomonas aeruginosa with high antimicrobial resistance have steadily emerged, threatening the utility of a mainstay in antipseudomonal therapy. This study evaluated the antimicrobial activities of various combination therapi
Autor:
Yuejun Sun, Yuyin Li, Jianjun Wang, Yueying Zhang, Zhenxing Liu, Lifang Jing, Aipo Diao, Yali Yan, Yajuan Feng, Long Ma
Publikováno v:
Chemotherapy. 62:85-93
The lysosome inhibitors bafilomycin A1 and chloroquine have both lysosomotropic properties and autophagy inhibition ability, and are promising clinical agents to be used in combination with anticancer drugs. In order to investigate this combination e
Publikováno v:
Chemotherapy. 62:94-99
Determination of the mutant prevention concentration (MPC) and the mutant selection window (MSW) of antimicrobial agents used to treat pathogenic bacteria is important in order to apply effective antimicrobial therapies. Here, we determined the MPCs