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Autor:
Swati Srivastava, Iti Garg, Vikas Dogra, Mona Bargotya, Sonali Bhattar, Utkarsh Gupta, Shruti Jain, Javid Hussain, Anju A. Hembrom, Nilanjana Ghosh, Vinay Kumar, Rajeev Varshney, Lilly Ganju
Publikováno v:
Pathobiology. 89:407-417
Introduction: Coronavirus disease 2019 (COVID-19) is a novel viral disease that spread as a global pandemic in 2020 by infecting millions of people across the world. Its clinical prognosis is dependent on various coagulatory parameters since thrombot
Autor:
Sara Costa Granja, Adhemar Longatto-Filho, Priscila B. de Campos, Claudia P. Oliveira, José T. Stefano, Sebastião N. Martins-Filho, Aline L. Chagas, Paulo Herman, Luiz C. D’Albuquerque, Mário Reis Alvares-da-Silva, Flair José Carrilho, Fátima Baltazar, Venâncio A.F. Alves
Publikováno v:
Pathobiology. 89:157-165
Introduction: Hepatocellular carcinoma (HCC) has been associated to non-alcoholic fatty liver disease (NAFLD). We sought to investigate the immunoexpression of several glycolytic metabolism-associated markers in patients with HCC associated to NAFLD
Publikováno v:
Pathobiology. 89:324-333
Immunohistochemistry techniques have been incorporated into surgical pathology for nearly a half-century and have since become intimately intertwined with its practice. In the realm of breast pathology, immunohistochemistry serves several purposes, i
Publikováno v:
Pathobiology. 89:233-244
Background: Long non-coding RNAs are reportedly endowed with the function of promoting or inhibiting cancer occurrence and development. The emphasis of this study was placed on the effect of lncRNA HLA complex group 11 (HCG11) on glioma progression,
Autor:
Islam M. Miligy, Michael S. Toss, Kylie L. Gorringe, Ian O. Ellis, Andrew R. Green, Emad A. Rakha
Publikováno v:
Pathobiology. 89:382-392
Introduction: Aurora Kinase A (AURKA/STK15) has a role in centrosome duplication and is a regulator of mitotic cell proliferation. It is over-expressed in breast cancer and other cancers, however; its role in ductal carcinoma in situ (DCIS) remains t
Autor:
Zaibo, Li, David J, Dabbs
Publikováno v:
Pathobiology. 89:309-323
Immunohistochemistry (IHC) plays an important role in the evaluation of breast pathology specimens to provide both diagnostic and prognostic/therapeutic information. Although most IHCs used in breast pathology can be easily interpreted, pitfalls do e
Autor:
Moien Lone, Mahaiwon Shadang, Qulsum Akhter, Mithilesh Kumar, Saumyaranjan Mallick, Ajay Gogia, Nilima Nilima, Shyam S. Chauhan, Riyaz A. Mir
Publikováno v:
Pathobiology. 89:146-156
Introduction: Diffuse large B-cell lymphoma (DLBCL) is the most prevalent subtype of non-Hodgkin’s lymphoma (NHL) accounting for 30% of adult NHL worldwide and 50% in developing countries like India. DNA damage and Myc-induced transformation are we
Autor:
Daniel Pinto, Fernando C. Schmitt
Publikováno v:
Pathobiology. 89:343-358
Fine-needle aspiration biopsies (FNABs) of the breast are minimally invasive procedures enabling the diagnosis of suspicious breast lesions. Unfortunately, they are often perceived as inferior to core-needle biopsies, namely because they are supposed
Publikováno v:
Microbial Physiology. 32:146-157
The human population is plagued by hundreds of infectious agents that cause diseases, and many of these agents can infect a range of wild and domesticated animals as well. In fact, a large proportion of current pathological conditions in humans is ca
Autor:
Kazuyoshi Yanagihara, Yuki Iino, Hiroshi Yokozaki, Takanori Kubo, Tatsuya Oda, Takashi Kubo, Masayuki Komatsu, Hiroki Sasaki, Hitoshi Ichikawa, Takeshi Kuwata, Toshio Seyama, Atsushi Ochiai
Publikováno v:
Pathobiology. 89:222-232
Background: Pancreatic ductal adenocarcinoma (PDA) is associated with very poor prognoses. Therefore, new therapies and preclinical models are urgently needed. In the present study, we sought to develop more realistic experimental models for use in P