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Autor:
Ines Beilmann-Lehtonen, Ulf-Håkan Stenman, Caj Haglund, Tuomas Kaprio, Kajsa Björkman, Camilla Böckelman
Publikováno v:
Oncology. 100:22-30
Objectives: Colorectal cancer is the third most common cancer worldwide, with an obvious need for more accurate prognostics. Previous studies identified C-reactive protein (CRP) as a prognostic serum biomarker for colorectal cancer, whereas the bioma
Autor:
Mariko Kobayashi, Satoshi Saitoh, Nozomu Muraishi, Masahiro Kobayashi, Fumitaka Suzuki, Kenji Ikeda, Norio Akuta, Yasuji Arase, Shunichiro Fujiyama, Hiromitsu Kumada, Tetsuya Hosaka, Hitomi Sezaki, Yusuke Kawamura, Yoshiyuki Suzuki
Publikováno v:
Oncology
Introduction: It is unclear whether the relationships between changes in fibrosis and circulating microRNA-122 (miR-122) dynamics might influence the prognosis of nonalcoholic fatty liver disease (NAFLD). Methods: This study investigates the impact o
Autor:
Jan-Peter Roth, Francesco Vitali, Dagmar Busse, W Schreiner, Susanne Merkel, Robert Stoehr, Arndt Hartmann, Markus Eckstein, Axel Wein, Stephan Kersting, Michael Uder, Peter Anhut, Robert Grützmann, Jürgen Siebler, Nicola Ostermeier, Markus F. Neurath, Kerstin Wolff, Clemens Neufert
Publikováno v:
Oncology. 100:1-11
Objective: The study aimed to prospectively evaluate a new molecular biomarker panel (KRAS, NRAS, BRAF, PIK3CA, and ERBB2) for palliative first-line treatment of colorectal cancer (CRC), including a multidisciplinary treatment approach. The rate of s
Autor:
Alla Berlin, Leora Brazg Ferro, Ester Osher, Orit Gutfeld, Inbal Golomb, Inna Ospovat, Viacheslav Soyfer, Ido Wolf, Shira Peleg Hasson
Publikováno v:
Oncology. 99:373-379
Introduction: Extrapulmonary small-cell cancer (EPSCC) is a relatively rare malignancy. The management of EPSCC is usually extrapolated from small-cell lung cancer (SCLC). In spite of the morphological similarity of the 2 malignancies, there are many
Autor:
Thomas Wolfram Paul Friedl, Wolfgang Janni, Davut Dayan, Amelie de Gregorio, Jens Huober, Nikolaus de Gregorio, Eva Hering, Peter Widschwendter, Inga Bekes
Publikováno v:
Oncology. 99:780-789
Introduction: Ki67 as a proliferative marker has prognostic and therapeutic relevance in early breast cancer (EBC). However, standard cutoffs for distinguishing low and high Ki67 do not exist. Material and Methods: Data from all patients treated at t
Autor:
Kotaro Yamashita, Makoto Yamasaki, Hidetoshi Eguchi, Yuichiro Doki, Tomoki Makino, Kiyokazu Nakajima, Takuro Saito, Norihiro Matsuura, Yukinori Kurokawa, Tsuyoshi Takahashi, Koji Tanaka, Yutaka Kimura, Masaaki Motoori, Kazuyoshi Yamamoto
Publikováno v:
Oncology. 99:547-554
Purpose: Esophageal cancer patients may simultaneously have resectable esophageal cancer and undiagnosable incidental minute solid pulmonary nodules. While the latter is rarely metastatic, only a few studies have reported on the outcomes of such nodu
Autor:
Hiroaki Motoyama, Hikaru Hayashi, Kentaro Fukushima, Yuji Soejima, Shinsuke Sugenoya, Koji Kubota, Kiyotaka Hosoda, Koya Yasukawa, Akira Shimizu, Ryoichiro Kobayashi, Tsuyoshi Notake
Publikováno v:
Oncology. 99:703-712
Introduction: The usefulness of adjuvant chemotherapy in biliary tract cancer (BTC) is poorly reported. This study aimed to evaluate the effectiveness and safety of adjuvant gemcitabine plus S-1 (GS) chemotherapy after curative surgical resection for
Autor:
Naoki Kamachi, Masahito Nakano, Takashi Niizeki, Takumi Kawaguchi, Takuji Torimura, Shigeo Shimose, Hironori Koga, Yu Noda, Ryoko Kuromatsu, Masatoshi Tanaka, Tomotake Shirono, Shusuke Okamura, Hideki Iwamoto, Akira Kajiwara
Publikováno v:
Oncology. 99:756-765
Background & Aims: Intermediate hepatocellular carcinoma (HCC) treatment has become complicated due to the development of various molecular-targeted agents (MTAs). We aimed to determine whether the administration of MTAs in patients with intermediate
Publikováno v:
Oncology Research and Treatment. 44:93-102
Background/Aim: Chemotherapy-induced neutropenia is a common and serious complication in cancer patients receiving myelosuppressive chemotherapy. This analysis was undertaken to evaluate the effectiveness and safety of prophylaxis with lipegfilgrasti
Autor:
Brian D. Badgwell, Catherine E Devine, Yang Lu, Jane E. Rogers, Ahmed Abdelhakeem, Allison Trail, Naruhiko Ikoma, Tara Sagebiel, Xuemei Wang, Jeannelyn S. Estrella, Madhavi Patnana, Jaffer A. Ajani, Mariela A. Blum Murphy
Publikováno v:
Oncology. 99:659-664
Background: The value of baseline fluorodeoxyglucose-positron emission tomography-computed tomography (PET-CT) remains uncertain once gastroesophageal cancer is metastatic. We hypothesized that assessment of detailed PET-CT parameters (maximum standa