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Autor:
Xuemei Huang, Toni I. Pollin, Alan R. Shuldiner, Lan Kong, Katherine A. Ryan, Honglei Chen, Richard B. Mailman, John W. Stiller, Mary Pavlovich, Teodor T. Postolache, Michael Goldenberg, Braxton D. Mitchell
Publikováno v:
Neuroepidemiology
Introduction: Previous research has suggested that the Amish may experience a relatively high prevalence of Parkinson’s disease (PD) and/or parkinsonian motor signs. Methods: In a large sample from the Amish community in Lancaster County, Pennsylva
Autor:
Jiadi Xu, Peter C.M. van Zijl, Hanzhang Lu, Wanli W. Smith, Lin Chen, Gongbo Guo, Chunming Gu, Christopher A. Ross, Hongshuai Liu, Jun Hua, Xiaofei He, Peiying Liu, Bo Ning, Wenzhen Duan, Zhiliang Wei, Adnan Bibic
Publikováno v:
Neurodegener Dis
Background: Parkinson’s disease (PD) is the second most common neurodegenerative disease and the most common movement disorder characterized by motor impairments resulting from midbrain dopamine neuron loss. Abnormalities in small pial arteries and
Autor:
Yangyang Duan, Feng Wang, Fengting Zhang, Haining Li, Shaoqing Lin, Andy Li, Hui Li, Luxuan Wang, Guowei Wang
Publikováno v:
Neurodegenerative Diseases. 19:204-210
Background: Parkinson’s disease (PD) is a neurodegenerative disease characterized by intracellular α-synuclein (α-Syn) deposition. Alternation of the α-Syn expression level in plasma or erythrocytes may be used as a potential PD biomarker. Howev
Publikováno v:
Neurodegenerative Diseases. 19:155-162
Introduction: We aimed to investigate the change of serum indirect bilirubin (IBIL) concentrations in patients with Parkinson’s disease (PD) and whether IBIL concentrations were associated with the motor subtypes of PD. Methods: A case-control stud
Publikováno v:
Neuroepidemiology, vol 52, iss 3-4
Neuroepidemiology, 52(3-4), 136-143. S. Karger AG
Neuroepidemiology, 52(3-4), 136-143. S. Karger AG
Cancer patients are at lower risk of developing Parkinson’s disease (PD) compared with the general population. One explanation is the negative association between smoking and PD, but PD risk is also lower for cancers not related to smoking. Another
Autor:
Esteban Muñoz, Ana Cámara, Yaroslau Compta, John Alexander Hoyos, Francesc Valldeoriola, Jordi Rumià, Pedro Roldan Ramos, Yislenz Narváez-Martínez, María-José Martí, Diego Culebras
Publikováno v:
Stereotactic and Functional Neurosurgery. 97:101-105
Background/Aims: Internal pulse generator (IPG) replacement is considered a relatively minor surgery but exposes the deep brain stimulation system to the risk of infectious and mechanical adverse events. We retrospectively reviewed complications asso
Publikováno v:
Neuroepidemiology. 53:63-72
Background: There is lack of data on the incidence of Parkinson’s disease (PD) based on repeat studies. Mortality rates of PD in Estonia have never been studied before. Objectives: To estimate the incidence and mortality rates of PD in Estonia, t
Autor:
Judith Tsamir, Nir Giladi, Baruch El-Ad, Chava Peretz, Tanya Gurevich, Beatriz Hemo, Violetta Rozani
Publikováno v:
Neuroepidemiology. 53:13-19
Background: To estimate the survival of a population-based cohort of Parkinson’s disease (PD) patients stratified by age and sex over a 13-year period. Methods: The dynamic PD cohort included 6,622 incident PD patients who initiated anti-parkinsoni
Autor:
Joke M. Dijk, Rob M.A. de Bie, Okker Verhagen, Matthan W.A. Caan, Vincent J. J. Odekerken, Y Dilai, Maarten Bot, Wouter V. Potters, Pepijn van den Munckhof, P. Richard Schuurman
Publikováno v:
Stereotactic and functional neurosurgery, 97(3), 153-159. S. Karger AG
Background: 7.0-T T2-weighted MRI offers excellent visibility of the subthalamic nucleus (STN), which is used as a target for deep brain stimulation (DBS) in Parkinson’s disease (PD). A comparison of 7.0-T MRI to microelectrode recordings (MER) for
Publikováno v:
European Neurology. 81:246-253
Introduction: Several studies have identified a number of genes associated with Parkinson’s disease (PD). Genomic rearrangements (exon dosage variations) in these genes have emerged as significant, causing mutations. However, exon dosage variations