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Autor:
Ines Beilmann-Lehtonen, Ulf-Håkan Stenman, Caj Haglund, Tuomas Kaprio, Kajsa Björkman, Camilla Böckelman
Publikováno v:
Oncology. 100:22-30
Objectives: Colorectal cancer is the third most common cancer worldwide, with an obvious need for more accurate prognostics. Previous studies identified C-reactive protein (CRP) as a prognostic serum biomarker for colorectal cancer, whereas the bioma
Autor:
Alla Berlin, Leora Brazg Ferro, Ester Osher, Orit Gutfeld, Inbal Golomb, Inna Ospovat, Viacheslav Soyfer, Ido Wolf, Shira Peleg Hasson
Publikováno v:
Oncology. 99:373-379
Introduction: Extrapulmonary small-cell cancer (EPSCC) is a relatively rare malignancy. The management of EPSCC is usually extrapolated from small-cell lung cancer (SCLC). In spite of the morphological similarity of the 2 malignancies, there are many
Autor:
Caj Haglund, Tuomas Kaprio, Jaana Hagström, Ines Beilmann-Lehtonen, Karin Strigård, Richard Palmqvist, Ulf-Håkan Stenman, Ulf Gunnarsson, Camilla Böckelman
Publikováno v:
Oncology. 99:790-801
Background: Colorectal cancer (CRC) is the third most commonly diagnosed malignancy globally. CRC patients with elevated plasma C-reactive protein (CRP) levels exhibit compromised prognoses. Toll-like receptors (TLRs), activating the innate and adapt
Autor:
Savtaj S. Brar, Carol Jane Swallow, Charles Henry Lim, Hao-Wen Sim, Jennifer J. Knox, Bryan A. Chan, Akina Natori, James Brierley, Osvaldo Espin-Garcia, Rebecca Wong, Jolie Ringash, Eric Chen, Elena Elimova, Sara Hafezi-Bakhtiari, John Kim, Raymond Woo-Jun Jang, Di Maria Jiang, Geoffrey Liu, Patrik Rogalla, Gail Darling, Stephanie Moignard
Publikováno v:
Oncology. 99:49-56
Background: Trimodality therapy (TMT) with neoadjuvant chemoradiotherapy (nCRT) using concurrent carboplatin plus paclitaxel (CP) followed by surgery is the standard of care for locoregional esophageal or gastroesophageal junction (GEJ) cancers. Alte
Autor:
Diana Pettinato, Alfredo Mirandola, Francesca Zanellini, Amelia Barcellini, Marianna Roccio, Francesca Valvo, Ester Orlandi, Angiolo Gadducci, Concetta Laliscia
Publikováno v:
Oncology. 99:65-71
Background and Summary: The management of endometrial cancer, in an ever-older population with considerable comorbidity, remains a challenge for gynecological and radiation oncologists. Key Message: The present paper reviews literature data on treatm
Autor:
Hitomi Sezaki, Yasuji Arase, Kenji Ikeda, Mariko Kobayashi, Fumitaka Suzuki, Tetsuya Hosaka, Yoshiyuki Suzuki, Masahiro Kobayashi, Yusuke Kawamura, Satoshi Saitoh, Shunichiro Fujiyama, Hiromitsu Kumada, Norio Akuta
Publikováno v:
Oncology. 99:114-123
Introduction: It remains unclear whether TERT promoter mutation (TERT C228T) in serum cell-free DNA (cfDNA) is useful for the diagnosis of hepatocellular carcinoma (HCC) in patients with nonalcoholic fatty liver disease (NAFLD). Methods: In this retr
Autor:
Sarah Humez, David Gentien, Pierre Mordant, Yves Castier, Jean-Yves Scoazec, Nathalie Théou-Anton, Anne Couvelard, Cécile Reyes, Louis de Mestier, Alice Guyard, Serge Guyétant, Vincent Thomas de Montpréville, Philippe Ruszniewski, Aurélie Cazes, Gérard Zalcman, Jérôme Cros, Ségolène Hescot, Valérie Gounant, S. Brosseau, Rémy Nicolle
Publikováno v:
Neuroendocrinology. 111:158-169
Introduction: High-grade lung neuroendocrine tumours with carcinoid morphology have been recently reported; they may represent the thoracic counterparts of grade 3 digestive neuroendocrine tumours. We aimed to study their genetic landscape including
Autor:
Kazuaki Tanabe, Naohiro Uraoka, Hideki Ohdan, Naoya Sakamoto, Narutaka Katsuya, Yuji Yamamoto, Ryuichi Asai, Naohide Oue, Wataru Yasui, Kazuhiro Sentani
Publikováno v:
Pathobiology. 87:254-261
Objectives: Esophageal cancer is the sixth most common malignancy worldwide. Signal peptidase complex 18 (SPC18) protein, which is encoded by the SEC11A gene, is one of the subunits of the signal peptidase complex and plays an important role in the s
Autor:
Alessandra Rubagotti, Elisa Zanardi, Sandra Salvi, Linda Zinoli, Chiara Boccardo, Antonio Di Meglio
Publikováno v:
Oncology Research and Treatment. 43:362-371
Introduction: Our understanding of the granularity of breast cancer (BC) clinical outcomes by biologic subtype may be impaired by limited study follow-up times. Objective: We evaluated the impact of modern immunohistochemistry (IHC)-based BC subtypes
Autor:
Nikolaus de Gregorio, Peter Widschwendter, Wolfgang Janni, Amelie de Gregorio, Arkadius Polasik, Thomas W. P. Friedl
Publikováno v:
Oncology Research and Treatment. 43:87-95
Background: Nodal status is the most important prognostic factor in cervical cancer. However, further risk stratification in node positive cervical cancer patients is warranted for optimal therapeutic decisions. Material and Methods: Nodal positive p