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pro vyhledávání: '"Zhimin Yin"'
Autor:
Shuai Lu, Jinyi Zhou, Chen Yang, Xiaoxue Zhang, Yingying Shi, Jie Liu, Xintong Yan, Juanjuan Liang, Xianli Liu, Lan Luo, Da Zhou, Zhimin Yin
Publikováno v:
Food & Function. 13:7560-7571
γ-glutamylcysteine activates SIRT1 by activating AMPK, promoting the nuclear translocation of GAPDH, while inhibiting that of DBC1. SIRT1 activation causes the deacetylation of p53 in the nucleus and inhibits the protein levels of p21 and p16.