Zobrazeno 1 - 10
of 291
pro vyhledávání: ''
Autor:
Shing Yen Lin, Tai Huang Huang, Shiu Mei Wang, Yu Sheng Lo, Chin Tien Wang, Ya Li Chiu, Ming-Hon Hou
Publikováno v:
Febs Letters
Highlights ► The role of the C-terminal tail of the HCoV-229E N protein in oligomerization. ► A correlation between oligomerization and thermostability. ► The C-terminal tail peptide interferes with the oligomerization. ► The development of d
Publikováno v:
FEBS Letters. (1):41-45
We have examined the effect of the 5′-flanking region of the human insulin gene on its expression in non-pancreatic cells. The presence of the region containing the insulin gene enhancer (−339 to −169 bp) markedly repressed the promoter activit
Autor:
Aideen Long, Dermot Kelleher
Publikováno v:
FEBS Letters. (3):243-247
The role of conventional protein kinase C (PKC) isoforms in the proliferation of a T cell lymphoma line was investigated, PKC isozyme-deficient cell lines were generated from HuT 78 which expresses PKC isoforms alpha, beta, epsilon and zeta. The firs
Publikováno v:
FEBS Letters. (1):100-104
Skin fibroblasts were selected as having cytochrome-c oxidase deficiency by activity mesurements in whole cells. Each cell line was cultured in sufficient amount to isolate mitochondria for biochemical characterization. Cytochrome-c oxidase was then
Publikováno v:
FEBS Letters. (1-2):189-193
The potent immunosuppressive drug FTY720, a sphingosine analog, induces redistribution of lymphocytes from circulation to secondary lymphoid tissues. FTY720 is phosphorylated in vivo and functions as an agonist for four G-protein-coupled sphingosine-
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. (3):183-186
Airway epithelial cells modulate the inflammatory response in asthmatic, allergic and fibrotic lung diseases through the secretion of cytokines that regulate the movement and activation of inflammatory cells. Mast cells play an important role in the
Autor:
Barry Halliwell, Ken Chimel, Jeremy P. E. Spencer, Andrew M. Jenner, Carroll E. Cross, Reen Wu, Okezie I. Aruoma
Publikováno v:
FEBS Letters. (3):179-182
Treatment of human respiratory tract tracheobronchial epithelial cells with gas-phase cigarette smoke led to dose-dependent DNA strand breakage that was highly correlated with multiple chemical modifications of all four DNA bases. The pattern of base
Autor:
Masahiro Okuda, Satohiro Masuda, Naoshi Horiba, Daisuke Takeuchi, Ken-ichi Inui, Chiharu Ohnishi
Publikováno v:
FEBS Letters. (2-3):276-280
We found a system of Na+-dependent uptake of fructose by rat renal brush-border membrane vesicles. It consisted of two saturable components, and was thought to involve at least two transporters. rNaGLT1, a novel glucose transporter in rat kidney, sho
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. (1):48-52
Human amnion-derived WISH cells synthesize little prostaglandin E2 at the basal state. However, the cells were stimulated greatly to synthesize prostaglandin E2 by interleukin-1beta in a dose-dependent manner. Stimulation by interleukin-1beta was syn
Autor:
Nancy J. Pollock, Arlene M. Manelli, Robert G. MacKenzie, Donald E. Frail, Michael E. Steffey
Publikováno v:
FEBS Letters. (1-2):59-62
D1 and D2 dopamine receptors are G-protein coupled receptors and have seven transmembrane spanning regions (TM) typical of this receptor superfamily. Although dopamine binds equally to D1 and D2 receptors, many compounds are highly selective. To prob