Zobrazeno 91 - 100
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Autor:
M Moreno, Fernando Goglia, R Thoma, Theo J. Visser, C Horst, M J Berry, P R Larsen, John W. Harney
Publikováno v:
FEBS Letters. (2-3):143-146
The prohormone thyroxine (T4) is activated by outer ring deiodination (ORD) to 3,3′,5-triiodothyronine (T3) and both hormones are degraded by inner ring deiodination (IRD) to 3,3′,5′-triiodothyronine (rT3) and 3,3′-diiodothyronine, respective
Publikováno v:
FEBS Letters. (1):171-175
1,2-sn-Dihexanoylglycerol (HHG) reduced the ATP content of HL-60 cells. This concentration-related (10-100 microM) effect reached a maximum of over 90%, was enantiomerically specific and not accompanied by release of lactate dehydrogenase. Oleoylacet
Autor:
Michael J. Berridge, Gillian M. Burgess, Peter C. Hoyle, James W. Putney, Jerry S. McKinney, Robin F. Irvine
Publikováno v:
FEBS Letters. (1):193-196
Pemeabilised, dimethyl sulphoxide-differentiated HL-60 human myelomonocytic leukemia cells accumulate 45Ca in an ATP-dependent manner. The 45Ca is taken up by a pool thought to be a component of the endoplasmic reticulum. Inositol trisphosphate induc
Publikováno v:
FEBS Letters. (2):214-218
The human P-glycoprotein gene family contains the mdr1 and the mdr3 gene. The mdr1 P-glycoprotein is over-expressed in multidrug resistant (MDR) tumor cells and is believed to play a role in the elimination of certain cytotoxic drugs used in the chem
Publikováno v:
FEBS Letters. (2):174-178
Cerebral deposition of betaA4 (beta-amyloid) peptide is a major pathological feature of Alzheimer's disease. Although the mechanism of betaA4 production from cells has been investigated extensively, so far little is known about the catabolism of the
Publikováno v:
FEBS Letters. (2):127-131
Monoclonal antibody LB-2 to a surface antigen on human B cells, lymphoblast, monocytes and vascular endothelial cells largely inhibited adhesion among Epstein Barr virus-immortalized normal B cells (EBV-B) and concanavalin A-stimulated blood mononucl
Publikováno v:
Scopus-Elsevier
Complementary DNA clones corresponding to human brain nitric oxide (NO) synthase have been isolated. The deduced amino acid sequence revealed an overall identity with rat brain NO synthase of about 93% and contained all suggested consensus sites for
Autor:
Rolf Kemler, Stefan Butz
Publikováno v:
FEBS Letters. (2):195-200
Catenins are peripheral cytoplasmic proteins originally identified in association with the mouse epithelial cell adhesion molecule E-cadherin. Molecular cloning and primary structure analysis demonstrated that alpha-catenin is homologous to vinculin
Publikováno v:
FEBS Letters. (20):3029-3032
A human cell line, in which expression of the ribosomal stalk proteins P1 and P2 has been suppressed by RNAi technology, has been used to test how the loss of these proteins affects IRES-dependent translation. Foot-and-mouth disease virus (FMDV) IRES
Publikováno v:
FEBS Letters. (1):1-6
Expression of catalytically active protein was detected in a murine mast cell line. The primary type of AChE mRNA produced by these cells was found to be the brain and muscle type by PCR amplification of alternative exons from the 3' of mast cells AC