Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Tetsuya Konishi"'
Autor:
Vengadeshprabhu Karuppagounder, Vijayasree V Giridharan, Somasundaram Arumugam, Remya Sreedhar, Suresh S Palaniyandi, Prasanna Krishnamurthy, Joao Quevedo, Kenichi Watanabe, Tetsuya Konishi, Rajarajan A Thandavarayan
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0152922 (2016)
The aim of this study was to investigate the role of macrophage polarization in aging heart. Macrophage differentiation is pathogenically linked to many inflammatory and immune disorders. It is often preceded by myocardial inflammation, which is char
Externí odkaz:
https://doaj.org/article/7f586af7a28c48748d565827c5dca0d6
Autor:
Naoto Tatewaki, Tetsuya Konishi, Yuki Nakajima, Miyako Nishida, Masafumi Saito, Takahiro Eitsuka, Toshiyuki Sakamaki, Nobuo Ikekawa, Hiroshi Nishida
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0147570 (2016)
Ataxia telangiectasia mutated (ATM) kinase plays a crucial role as a master controller in the cellular DNA damage response. Inhibition of ATM leads to inhibition of the checkpoint signaling pathway. Hence, addition of checkpoint inhibitors to antican
Externí odkaz:
https://doaj.org/article/59c9d1cde60b4be2a4e67f8b6e3a74db
Autor:
Rajarajan A Thandavarayan, Vijayasree V Giridharan, Somasundaram Arumugam, Kenji Suzuki, Kam Ming Ko, Prasanna Krishnamurthy, Kenichi Watanabe, Tetsuya Konishi
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0119214 (2015)
Doxorubicin (Dox) is a highly effective antineoplastic drug. However, Dox-induced apoptosis in cardiomyocytes leads to irreversible degenerative cardiomyopathy, which limits Dox clinical application. Schisandrin B (Sch B), a dibenzocyclooctadiene der
Externí odkaz:
https://doaj.org/article/0fcd12f50b214fefb49827e1630aad50
Autor:
Vijayasree V Giridharan, Rajarajan A Thandavarayan, Somasundaram Arumugam, Makoto Mizuno, Hiroyuki Nawa, Kenji Suzuki, Kam M Ko, Prasanna Krishnamurthy, Kenichi Watanabe, Tetsuya Konishi
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0142483 (2015)
Amyloid β (Aβ)-induced neurotoxicity is a major pathological mechanism of Alzheimer's disease (AD). Our previous studies have demonstrated that schisandrin B (Sch B), an antioxidant lignan from Schisandra chinensis, could protect mouse brain agains
Externí odkaz:
https://doaj.org/article/91ed6418732f45149ad434d64697ab3e
Autor:
Miyako Nishida, Hiroshi Nishida, Yuki Nakajima, Toshiyuki Sakamaki, Tetsuya Konishi, Naoto Tatewaki, Masafumi Saito, Takahiro Eitsuka, Nobuo Ikekawa
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0147570 (2016)
PLoS ONE
PLoS ONE
Ataxia telangiectasia mutated (ATM) kinase plays a crucial role as a master controller in the cellular DNA damage response. Inhibition of ATM leads to inhibition of the checkpoint signaling pathway. Hence, addition of checkpoint inhibitors to antican
Autor:
Kenichi Watanabe, Kenji Suzuki, Somasundaram Arumugam, Prasanna Krishnamurthy, Vijayasree V. Giridharan, Tetsuya Konishi, Kam Ming Ko, Rajarajan Amirthalingam Thandavarayan
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0119214 (2015)
PLoS ONE
PLoS ONE
Doxorubicin (Dox) is a highly effective antineoplastic drug. However, Dox-induced apoptosis in cardiomyocytes leads to irreversible degenerative cardiomyopathy, which limits Dox clinical application. Schisandrin B (Sch B), a dibenzocyclooctadiene der