Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Taru, Tukiainen"'
Autor:
Christoph Nowak, Samira Salihovic, Andrea Ganna, Stefan Brandmaier, Taru Tukiainen, Corey D Broeckling, Patrik K Magnusson, Jessica E Prenni, Rui Wang-Sattler, Annette Peters, Konstantin Strauch, Thomas Meitinger, Vilmantas Giedraitis, Johan Ärnlöv, Christian Berne, Christian Gieger, Samuli Ripatti, Lars Lind, Nancy L Pedersen, Johan Sundström, Erik Ingelsson, Tove Fall
Publikováno v:
PLoS Genetics, Vol 13, Iss 9, p e1007002 (2017)
[This corrects the article DOI: 10.1371/journal.pgen.1006379.].
Externí odkaz:
https://doaj.org/article/86a8eaf5ca494501ba2937d1165d153b
Autor:
Christoph Nowak, Samira Salihovic, Andrea Ganna, Stefan Brandmaier, Taru Tukiainen, Corey D Broeckling, Patrik K Magnusson, Jessica E Prenni, Rui Wang-Sattler, Annette Peters, Konstantin Strauch, Thomas Meitinger, Vilmantas Giedraitis, Johan Ärnlöv, Christian Berne, Christian Gieger, Samuli Ripatti, Lars Lind, Nancy L Pedersen, Johan Sundström, Erik Ingelsson, Tove Fall
Publikováno v:
PLoS Genetics, Vol 12, Iss 10, p e1006379 (2016)
Insulin resistance (IR) and impaired insulin secretion contribute to type 2 diabetes and cardiovascular disease. Both are associated with changes in the circulating metabolome, but causal directions have been difficult to disentangle. We combined unt
Externí odkaz:
https://doaj.org/article/8187e931d5e742748db883066ca5e4ab
Autor:
Elaine T Lim, Peter Würtz, Aki S Havulinna, Priit Palta, Taru Tukiainen, Karola Rehnström, Tõnu Esko, Reedik Mägi, Michael Inouye, Tuuli Lappalainen, Yingleong Chan, Rany M Salem, Monkol Lek, Jason Flannick, Xueling Sim, Alisa Manning, Claes Ladenvall, Suzannah Bumpstead, Eija Hämäläinen, Kristiina Aalto, Mikael Maksimow, Marko Salmi, Stefan Blankenberg, Diego Ardissino, Svati Shah, Benjamin Horne, Ruth McPherson, Gerald K Hovingh, Muredach P Reilly, Hugh Watkins, Anuj Goel, Martin Farrall, Domenico Girelli, Alex P Reiner, Nathan O Stitziel, Sekar Kathiresan, Stacey Gabriel, Jeffrey C Barrett, Terho Lehtimäki, Markku Laakso, Leif Groop, Jaakko Kaprio, Markus Perola, Mark I McCarthy, Michael Boehnke, David M Altshuler, Cecilia M Lindgren, Joel N Hirschhorn, Andres Metspalu, Nelson B Freimer, Tanja Zeller, Sirpa Jalkanen, Seppo Koskinen, Olli Raitakari, Richard Durbin, Daniel G MacArthur, Veikko Salomaa, Samuli Ripatti, Mark J Daly, Aarno Palotie, Sequencing Initiative Suomi (SISu) Project
Publikováno v:
PLoS Genetics, Vol 10, Iss 7, p e1004494 (2014)
Exome sequencing studies in complex diseases are challenged by the allelic heterogeneity, large number and modest effect sizes of associated variants on disease risk and the presence of large numbers of neutral variants, even in phenotypically releva
Externí odkaz:
https://doaj.org/article/220e35bc48b7409493a0e7462135b8ed
Autor:
Taru Tukiainen, Matti Pirinen, Antti-Pekka Sarin, Claes Ladenvall, Johannes Kettunen, Terho Lehtimäki, Marja-Liisa Lokki, Markus Perola, Juha Sinisalo, Efthymia Vlachopoulou, Johan G Eriksson, Leif Groop, Antti Jula, Marjo-Riitta Järvelin, Olli T Raitakari, Veikko Salomaa, Samuli Ripatti
Publikováno v:
PLoS Genetics, Vol 10, Iss 2, p e1004127 (2014)
The X chromosome (chrX) represents one potential source for the "missing heritability" for complex phenotypes, which thus far has remained underanalyzed in genome-wide association studies (GWAS). Here we demonstrate the benefits of including chrX in
Externí odkaz:
https://doaj.org/article/3a75df623fec463ca351ffe4a412f4fc
Autor:
Beatriz Valcárcel, Peter Würtz, Nafisa-Katrin Seich al Basatena, Taru Tukiainen, Antti J Kangas, Pasi Soininen, Marjo-Riitta Järvelin, Mika Ala-Korpela, Timothy M Ebbels, Maria de Iorio
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24702 (2011)
Variations in the pattern of molecular associations are observed during disease development. The comprehensive analysis of molecular association patterns and their changes in relation to different physiological conditions can yield insight into the b
Externí odkaz:
https://doaj.org/article/91a32ba1d1b2403595c69040b8af951d