Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Menendez, P."'
Autor:
Burcu Ünlütabak, Graciela Trujillo Hernandez, İlayda Velioğlu, David Menendez, Karl S Rosengren
Publikováno v:
PLoS ONE, Vol 19, Iss 7, p e0307475 (2024)
Question-asking is a crucial tool for acquiring information about unseen entities, such as viruses; thus, examining children's questions within the context of COVID-19 is particularly important for understanding children's learning about the coronavi
Externí odkaz:
https://doaj.org/article/fd6cb8789e234b97bf815dcab1245088
Autor:
Jessica Fletcher, James O'Connor-Moneley, Dean Frawley, Peter R Flanagan, Leenah Alaalm, Pilar Menendez-Manjon, Samuel Vega Estevez, Shane Hendricks, Andrew L Woodruff, Alessia Buscaino, Matthew Z Anderson, Derek J Sullivan, Gary P Moran
Publikováno v:
PLoS Genetics, Vol 19, Iss 12, p e1011082 (2023)
The Candida albicans genome contains between ten and fifteen distinct TLO genes that all encode a Med2 subunit of Mediator. In order to investigate the biological role of Med2/Tlo in C. albicans we deleted all fourteen TLO genes using CRISPR-Cas9 mut
Externí odkaz:
https://doaj.org/article/6874864e6b33490da8798f1d41d1bd22
Autor:
Laura S Danielson, Maria V Guijarro, Silvia Menendez, Brett Higgins, Qiang Sun, Khushbakhat Mittal, Dorota A Popiolek, Michael Overholtzer, Glyn D Palmer, Eva Hernando
Publikováno v:
PLoS ONE, Vol 18, Iss 1, p e0278844 (2023)
Leiomyosarcoma (LMS) is an aggressive, often poorly differentiated cancer of the smooth muscle (SM) lineage for which the molecular drivers of transformation and progression are poorly understood. In microRNA (miRNA) profiling studies, miR-130b was p
Externí odkaz:
https://doaj.org/article/811f590e1ad94d7687d8c31f9fb8336d
Autor:
Jose M Jimenez-Guardeño, Ana Maria Ortega-Prieto, Borja Menendez Moreno, Thomas J A Maguire, Adam Richardson, Juan Ignacio Diaz-Hernandez, Javier Diez Perez, Mark Zuckerman, Albert Mercadal Playa, Carlos Cordero Deline, Michael H Malim, Rocio Teresa Martinez-Nunez
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 7, p e1010330 (2022)
The COVID-19 pandemic has accelerated the need to identify new antiviral therapeutics at pace, including through drug repurposing. We employed a Quadratic Unbounded Binary Optimization (QUBO) model, to search for compounds similar to Remdesivir, the
Externí odkaz:
https://doaj.org/article/234164c14bf14ea2ada10ccfa2cb8509
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 6, p e1009062 (2022)
How does the brain prioritize among the contents of working memory (WM) to appropriately guide behavior? Previous work, employing inverted encoding modeling (IEM) of electroencephalography (EEG) and functional magnetic resonance imaging (fMRI) datase
Externí odkaz:
https://doaj.org/article/be84c5355c5345cca49c1169c1c54b74
Autor:
Duncan N Ndegwa, Prasun Kundu, Jessica B Hostetler, Alejandro Marin-Menendez, Theo Sanderson, Kioko Mwikali, Lisa H Verzier, Rachael Coyle, Sophie Adjalley, Julian C Rayner
Publikováno v:
PLoS Pathogens, Vol 17, Iss 7, p e1008864 (2021)
Plasmodium vivax is responsible for the majority of malaria cases outside Africa. Unlike P. falciparum, the P. vivax life-cycle includes a dormant liver stage, the hypnozoite, which can cause infection in the absence of mosquito transmission. An effe
Externí odkaz:
https://doaj.org/article/4197213a6623436ba9bf61b6c6a92439
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 6, p e1008408 (2021)
Tumour cell heterogeneity is a major barrier for efficient design of targeted anti-cancer therapies. A diverse distribution of phenotypically distinct tumour-cell subpopulations prior to drug treatment predisposes to non-uniform responses, leading to
Externí odkaz:
https://doaj.org/article/c6170dc9763e4c5ab5c1b3c8c8502350
Autor:
Rella Zoleko-Manego, Johannes Mischlinger, Jean Claude Dejon-Agobé, Arti Basra, J Rodolphe Mackanga, Daisy Akerey Diop, Ayola Akim Adegnika, Selidji T Agnandji, Bertrand Lell, Peter G Kremsner, Pierre Blaise Matsiegui, Raquel González, Clara Menendez, Michael Ramharter, Ghyslain Mombo-Ngoma
Publikováno v:
PLoS ONE, Vol 16, Iss 2, p e0246694 (2021)
BackgroundMalnutrition and low birth weight (LBW) are two common causes of morbidity and mortality among children in sub-Saharan Africa. Both malnutrition and LBW affect early childhood development with long term consequences that may vary in their d
Externí odkaz:
https://doaj.org/article/00e39f5f10d64131bb9c6d9c89ce2534
Autor:
David Menendez, Rebecca E Klapper, Michelle Z Golden, Ava R Mandel, Katrina A Nicholas, Maria H Schapfel, Olivia O Silsby, Kailee A Sowers, Dillanie Sumanthiran, Victoria E Welch, Karl S Rosengren
Publikováno v:
PLoS ONE, Vol 16, Iss 8, p e0256692 (2021)
Parent-child conversations are important for children's cognitive development, children's ability to cope with stressful events, and can shape children's beliefs about the causes of illness. In the context of a global pandemic, families have faced a
Externí odkaz:
https://doaj.org/article/d5862bd84eb14bed964ba8ecc8b6a6a9
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0253519 (2021)
The receptor-interacting protein kinase 3 (RIPK3) is a multi-functional protein best known for facilitating cellular necroptosis and inflammation. Recent evidence from our lab indicates that RIPK3 expression must be tightly regulated in endothelial c
Externí odkaz:
https://doaj.org/article/dcbecacf4371497d9d497a8de5be278a