Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Masafumi Ihara"'
Autor:
Yun-An Lim, Li Si Tan, Wei Thye Lee, Wei Liang Sim, Yang Lv, Maki Takakuni, Satoshi Saito, Masafumi Ihara, Thiruma Valavan Arumugam, Christopher Chen, Fred Wai-Shiu Wong, Gavin Stewart Dawe
Publikováno v:
PLoS ONE, Vol 19, Iss 4 (2024)
Externí odkaz:
https://doaj.org/article/ebf2b7c2bbd94aa28bee0a0af7771cbc
Autor:
Shinichi Wada, Manabu Inoue, Takayuki Matsuki, Takuya Okata, Masaya Kumamoto, Naoki Tagawa, Akira Okamoto, Toshiyuki Miyata, Masafumi Ihara, Masatoshi Koga, Kazunori Toyoda
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0214132 (2019)
BackgroundThe crushed-tablet rivaroxaban concentration has been previously reported to be lower than the non-crushed concentration. However, the rivaroxaban concentration of fine granules has not yet been investigated. The anticoagulation intensity o
Externí odkaz:
https://doaj.org/article/f5da3a66e84d4b47893ca0a54c5815df
Autor:
Shimpei Iikuni, Masahiro Ono, Hiroyuki Watanabe, Masashi Yoshimura, Hatsue Ishibashi-Ueda, Masafumi Ihara, Hideo Saji
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0163969 (2016)
Cerebral amyloid angiopathy (CAA) is characterized by the deposition of amyloid aggregates in the walls of the cerebral vasculature. Recently, the development of molecular imaging probes targeting CAA has been attracting much attention. We previously
Externí odkaz:
https://doaj.org/article/5d39046dc80d46f8aec4bd32fc648c02
Autor:
Masato Maesako, Maiko Uemura, Yoshitaka Tashiro, Kazuki Sasaki, Kiwamu Watanabe, Yasuha Noda, Karin Ueda, Megumi Asada-Utsugi, Masakazu Kubota, Katsuya Okawa, Masafumi Ihara, Shun Shimohama, Kengo Uemura, Ayae Kinoshita
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0131199 (2015)
Obesity and type 2 diabetes are risk factors of Alzheimer's disease (AD). We reported that a high fat diet (HFD) promotes amyloid precursor protein (APP) cleavage by β-site APP cleaving enzyme 1 (BACE1) without increasing BACE1 levels in APP transge
Externí odkaz:
https://doaj.org/article/d3c1b127c225412f90873488877015f6
Autor:
Tomotaka Tanaka, Hiroshi Yamagami, Masafumi Ihara, Rie Motoyama, Kazuki Fukuma, Tetsuya Miyagi, Kazutaka Nishimura, Kazunori Toyoda, Kazuyuki Nagatsuka
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0136200 (2015)
Seizure is a common complication after stroke (termed "post-stroke seizure," PSS). Although many studies have assessed outcomes and risk factors of PSS, no reliable predictors are currently available to determine PSS recurrence. We compared baseline
Externí odkaz:
https://doaj.org/article/cdacfe130fff4243871dc7cc5b86de30
Cilostazol add-on therapy in patients with mild dementia receiving donepezil: a retrospective study.
Autor:
Masafumi Ihara, Madoka Nishino, Akihiko Taguchi, Yumi Yamamoto, Yorito Hattori, Satoshi Saito, Yukako Takahashi, Masahiro Tsuji, Yukiko Kasahara, Yu Takata, Masahiro Okada
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89516 (2014)
GoalCombinatorial therapy directed at both vascular and neurodegenerative aspects of dementia may offer a promising strategy for treatment of dementia, which often has a multifactorial basis in the elderly. We investigated whether the phosphodiestera
Externí odkaz:
https://doaj.org/article/c75ae3b23cee4040b68e76e235998f3d
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100257 (2014)
BackgroundCarotid artery occlusive disease gradually develops over time, eventually leading to cerebral infarction and high mortality rate. Animal models replicating cerebral infarction resulting from carotid artery occlusive disease have thus been d
Externí odkaz:
https://doaj.org/article/d7c0c1ea29b24b58817aca16f1fc3d4c
Autor:
Ji Hae Seo, Takakuni Maki, Mitsuyo Maeda, Nobukazu Miyamoto, Anna C Liang, Kazuhide Hayakawa, Loc-Duyen D Pham, Fumihiko Suwa, Akihiko Taguchi, Tomohiro Matsuyama, Masafumi Ihara, Kyu-Won Kim, Eng H Lo, Ken Arai
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e103174 (2014)
Trophic coupling between cerebral endothelium and their neighboring cells is required for the development and maintenance of blood-brain barrier (BBB) function. Here we report that oligodendrocyte precursor cells (OPCs) secrete soluble factor TGF-β1
Externí odkaz:
https://doaj.org/article/59584deb9ae34d6998fd58c2ac00f6c6
Autor:
Masahiro Ono, Yan Cheng, Hiroyuki Kimura, Hiroyuki Watanabe, Kenji Matsumura, Masashi Yoshimura, Shimpei Iikuni, Yoko Okamoto, Masafumi Ihara, Ryosuke Takahashi, Hideo Saji
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74104 (2013)
Imaging of β-amyloid (Aβ) plaques in the brain may facilitate the diagnosis of cerebral β-amyloidosis, risk prediction of Alzheimer's disease (AD), and effectiveness of anti-amyloid therapies. The purpose of this study was to evaluate novel (123)I
Externí odkaz:
https://doaj.org/article/88f0203eb2224c83b97fd46640d134b1
Autor:
Youshi Fujita, Takahiro Kuchimaru, Tetsuya Kadonosono, Shotaro Tanaka, Yoshiki Hase, Hidekazu Tomimoto, Masahiro Hiraoka, Shinae Kizaka-Kondoh, Masafumi Ihara, Ryosuke Takahashi
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e48051 (2012)
Within the ischemic penumbra, blood flow is sufficiently reduced that it results in hypoxia severe enough to arrest physiological function. Nevertheless, it has been shown that cells present within this region can be rescued and resuscitated by resto
Externí odkaz:
https://doaj.org/article/aeef21fe4ca149b9b3ebc8fa3ecc59b4