Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Diane L Kamen"'
Autor:
Lauren L Ritterhouse, Rufei Lu, Hemangi B Shah, Julie M Robertson, Dustin A Fife, Holden T Maecker, Hongwu Du, Charles G Fathman, Eliza F Chakravarty, R Hal Scofield, Diane L Kamen, Joel M Guthridge, Judith A James
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94500 (2014)
In recent years, vitamin D has been shown to possess a wide range of immunomodulatory effects. Although there is extensive amount of research on vitamin D, we lack a comprehensive understanding of the prevalence of vitamin D deficiency or the mechani
Externí odkaz:
https://doaj.org/article/155df63b35f742e2a81da607d76b0d7e
Autor:
Yun Deng, Jian Zhao, Daisuke Sakurai, Kenneth M Kaufman, Jeffrey C Edberg, Robert P Kimberly, Diane L Kamen, Gary S Gilkeson, Chaim O Jacob, R Hal Scofield, Carl D Langefeld, Jennifer A Kelly, Rosalind Ramsey-Goldman, Michelle A Petri, John D Reveille, Luis M Vilá, Graciela S Alarcón, Timothy J Vyse, Bernardo A Pons-Estel, Argentine Collaborative Group, Barry I Freedman, Patrick M Gaffney, Kathy Moser Sivils, Judith A James, Peter K Gregersen, Juan-Manuel Anaya, Timothy B Niewold, Joan T Merrill, Lindsey A Criswell, Anne M Stevens, Susan A Boackle, Rita M Cantor, Weiling Chen, Jeniffer M Grossman, Bevra H Hahn, John B Harley, Marta E Alarcόn-Riquelme, BIOLUPUS and GENLES networks, Elizabeth E Brown, Betty P Tsao
Publikováno v:
PLoS Genetics, Vol 9, Iss 2, p e1003336 (2013)
We previously reported that the G allele of rs3853839 at 3'untranslated region (UTR) of Toll-like receptor 7 (TLR7) was associated with elevated transcript expression and increased risk for systemic lupus erythematosus (SLE) in 9,274 Eastern Asians [
Externí odkaz:
https://doaj.org/article/e01c7a6e68b7433fab433c9fe327b367
Autor:
Harinder Manku, Carl D Langefeld, Sandra G Guerra, Talat H Malik, Marta Alarcon-Riquelme, Juan-Manuel Anaya, Sang-Cheol Bae, Susan A Boackle, Elizabeth E Brown, Lindsey A Criswell, Barry I Freedman, Patrick M Gaffney, Peter A Gregersen, Joel M Guthridge, Sang-Hoon Han, John B Harley, Chaim O Jacob, Judith A James, Diane L Kamen, Kenneth M Kaufman, Jennifer A Kelly, Javier Martin, Joan T Merrill, Kathy L Moser, Timothy B Niewold, So-Yeon Park, Bernardo A Pons-Estel, Amr H Sawalha, R Hal Scofield, Nan Shen, Anne M Stevens, Celi Sun, Gary S Gilkeson, Jeff C Edberg, Robert P Kimberly, Swapan K Nath, Betty P Tsao, Tim J Vyse
Publikováno v:
PLoS Genetics, Vol 9, Iss 7, p e1003554 (2013)
We previously established an 80 kb haplotype upstream of TNFSF4 as a susceptibility locus in the autoimmune disease SLE. SLE-associated alleles at this locus are associated with inflammatory disorders, including atherosclerosis and ischaemic stroke.
Externí odkaz:
https://doaj.org/article/b2196afc1ed34573a4882b40747d22a9
Autor:
Daisuke Sakurai, Jian Zhao, Yun Deng, Jennifer A Kelly, Elizabeth E Brown, John B Harley, Sang-Cheol Bae, Marta E Alarcόn-Riquelme, BIOLUPUS and GENLES networks, Jeffrey C Edberg, Robert P Kimberly, Rosalind Ramsey-Goldman, Michelle A Petri, John D Reveille, Luis M Vilá, Graciela S Alarcón, Kenneth M Kaufman, Timothy J Vyse, Chaim O Jacob, Patrick M Gaffney, Kathy Moser Sivils, Judith A James, Diane L Kamen, Gary S Gilkeson, Timothy B Niewold, Joan T Merrill, R Hal Scofield, Lindsey A Criswell, Anne M Stevens, Susan A Boackle, Jae-Hoon Kim, Jiyoung Choi, Bernardo A Pons-Estel, Argentine Collaborative Group, Barry I Freedman, Juan-Manuel Anaya, Javier Martin, C Yung Yu, Deh-Ming Chang, Yeong Wook Song, Carl D Langefeld, Weiling Chen, Jennifer M Grossman, Rita M Cantor, Bevra H Hahn, Betty P Tsao
Publikováno v:
PLoS Genetics, Vol 9, Iss 10, p e1003870 (2013)
Immunoregulatory cytokine interleukin-10 (IL-10) is elevated in sera from patients with systemic lupus erythematosus (SLE) correlating with disease activity. The established association of IL10 with SLE and other autoimmune diseases led us to fine ma
Externí odkaz:
https://doaj.org/article/33558ef9795b4c2f9aa7967c0abd4a4d
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63725 (2013)
Systemic lupus erythematosus (SLE) is a chronic systemic autoimmune disease that disproportionately affects African American females. The causes of SLE are unknown but postulated to be a combination of genetic predisposition and environmental trigger
Externí odkaz:
https://doaj.org/article/1045b03ec2234b35b2739efba468c4e6
Autor:
Jian Zhao, Hui Wu, Melanie Khosravi, Huijuan Cui, Xiaoxia Qian, Jennifer A Kelly, Kenneth M Kaufman, Carl D Langefeld, Adrienne H Williams, Mary E Comeau, Julie T Ziegler, Miranda C Marion, Adam Adler, Stuart B Glenn, Marta E Alarcón-Riquelme, BIOLUPUS Network, GENLES Network, Bernardo A Pons-Estel, John B Harley, Sang-Cheol Bae, So-Young Bang, Soo-Kyung Cho, Chaim O Jacob, Timothy J Vyse, Timothy B Niewold, Patrick M Gaffney, Kathy L Moser, Robert P Kimberly, Jeffrey C Edberg, Elizabeth E Brown, Graciela S Alarcon, Michelle A Petri, Rosalind Ramsey-Goldman, Luis M Vilá, John D Reveille, Judith A James, Gary S Gilkeson, Diane L Kamen, Barry I Freedman, Juan-Manuel Anaya, Joan T Merrill, Lindsey A Criswell, R Hal Scofield, Anne M Stevens, Joel M Guthridge, Deh-Ming Chang, Yeong Wook Song, Ji Ah Park, Eun Young Lee, Susan A Boackle, Jennifer M Grossman, Bevra H Hahn, Timothy H J Goodship, Rita M Cantor, Chack-Yung Yu, Nan Shen, Betty P Tsao
Publikováno v:
PLoS Genetics, Vol 7, Iss 5, p e1002079 (2011)
Systemic lupus erythematosus (SLE), a complex polygenic autoimmune disease, is associated with increased complement activation. Variants of genes encoding complement regulator factor H (CFH) and five CFH-related proteins (CFHR1-CFHR5) within the chro
Externí odkaz:
https://doaj.org/article/714680860d754c02ba45e9b2d825dcfd
Autor:
Ilan Ben-Zvi, Cynthia Aranow, Meggan Mackay, Anfisa Stanevsky, Diane L Kamen, L Manuela Marinescu, Christopher E Collins, Gary S Gilkeson, Betty Diamond, John A Hardin
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9193 (2010)
Excessive activity of dendritic cells (DCs) is postulated as a central disease mechanism in Systemic Lupus Erythematosus (SLE). Vitamin D is known to reduce responsiveness of healthy donor DCs to the stimulatory effects of Type I IFN. As vitamin D de
Externí odkaz:
https://doaj.org/article/b249c53d0a5441e1948b59a9379f318b
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63725 (2013)
PLoS ONE
PLoS ONE
Systemic lupus erythematosus (SLE) is a chronic systemic autoimmune disease that disproportionately affects African American females. The causes of SLE are unknown but postulated to be a combination of genetic predisposition and environmental trigger
Autor:
Anne M. Stevens, Timothy B. Niewold, Juan-Manuel Anaya, Chaim O. Jacob, Diane L. Kamen, Patrick M. Gaffney, Barry I. Freedman, Susan A. Boackle, Sandra G. Guerra, John B. Harley, Robert P. Kimberly, Bernardo A. Pons-Estel, Joan T. Merrill, R. Hal Scofield, Marta E. Alarcón-Riquelme, Elizabeth E. Brown, Kenneth M. Kaufman, Joel M. Guthridge, Carl D. Langefeld, Timothy J. Vyse, Javier Martin, Soyeon Park, Sang Hoon Han, Betty P. Tsao, Talat H. Malik, Jennifer A. Kelly, Harinder Manku, Judith A. James, Kathy L. Moser, Nan Shen, Celi Sun, Gary S. Gilkeson, Lindsey A. Criswell, Amr H. Sawalha, Sang Cheol Bae, Swapan K. Nath, Jeffrey C. Edberg, Peter A. Gregersen
Publikováno v:
PLoS Genetics, Vol 9, Iss 7, p e1003554 (2013)
Digital.CSIC. Repositorio Institucional del CSIC
instname
PLoS Genetics
Repositorio EdocUR-U. Rosario
Universidad del Rosario
instacron:Universidad del Rosario
Digital.CSIC. Repositorio Institucional del CSIC
instname
PLoS Genetics
Repositorio EdocUR-U. Rosario
Universidad del Rosario
instacron:Universidad del Rosario
We previously established an 80 kb haplotype upstream of TNFSF4 as a susceptibility locus in the autoimmune disease SLE. SLE-associated alleles at this locus are associated with inflammatory disorders, including atherosclerosis and ischaemic stroke.