Zobrazeno 1 - 8
of 8
pro vyhledávání: '"David Lyden"'
Autor:
Knut M Wittkowski, Christina Dadurian, Martin P Seybold, Han Sang Kim, Ayuko Hoshino, David Lyden
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0214826 (2019)
[This corrects the article DOI: 10.1371/journal.pone.0199012.].
Externí odkaz:
https://doaj.org/article/cf38b4e6c11e4e32b60bceb3a8895afc
Autor:
Knut M Wittkowski, Christina Dadurian, Martin P Seybold, Han Sang Kim, Ayuko Hoshino, David Lyden
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0199012 (2018)
Most breast cancer deaths are caused by metastasis and treatment options beyond radiation and cytotoxic drugs, which have severe side effects, and hormonal treatments, which are or become ineffective for many patients, are urgently needed. This study
Externí odkaz:
https://doaj.org/article/9b5a03d2b11c463a9f5bfa7858311c06
Autor:
Janeen Azare, Ashley Doane, Kenneth Leslie, Qing Chang, Marjan Berishaj, Jennifer Nnoli, Kevin Mark, Hikmat Al-Ahmadie, William Gerald, Maryam Hassimi, Agnes Viale, Mary Stracke, David Lyden, Jacqueline Bromberg
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27851 (2011)
We determined that signal transducer and activator of transcription 3 (Stat3) is tyrosine phosphorylated in 37% of primary breast tumors and 63% of paired metastatic axillary lymph nodes. Examination of the distribution of tyrosine phosphorylated (pS
Externí odkaz:
https://doaj.org/article/9ba590145ac748df97b18c28a44fa8d7
Autor:
April S Chan, Kristian K Jensen, Dimitris Skokos, Stephen Doty, Hannah K Lederman, Rosandra N Kaplan, Shahin Rafii, Stefano Rivella, David Lyden
Publikováno v:
PLoS ONE, Vol 4, Iss 11, p e7955 (2009)
The bone-bone marrow interface is an area of the bone marrow microenvironment in which both bone remodeling cells, osteoblasts and osteoclasts, and hematopoietic cells are anatomically juxtaposed. The close proximity of these cells naturally suggests
Externí odkaz:
https://doaj.org/article/e4debfe3414c41deb8874fd33d878855
Autor:
Knut M. Wittkowski, Christina Dadurian, Martin P. Seybold, Han Sang Kim, Ayuko Hoshino, David Lyden
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 3, p e0214826 (2019)
PLoS ONE, Vol 14, Iss 3, p e0214826 (2019)
Most breast cancer deaths are caused by metastasis and treatment options beyond radiation and cytotoxic drugs, which have severe side effects, and hormonal treatments, which are or become ineffective for many patients, are urgently needed. This study
Autor:
Kevin C. De Braganca, Jill M. Kolesar, Yasmin Khakoo, Tanya M. Trippett, Kim Kramer, Shakeel Modak, Stephen Gilheeney, Brian H. Kushner, Oren J. Becher, Jason T. Huse, Nai-Kong V. Cheung, David Lyden, Nathan E. Millard, Sofia Haque, Ira J. Dunkel, Ivan Spasojevic
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0178593 (2017)
PLoS ONE
PLoS ONE
The PI3K/Akt/mTOR signaling pathway is aberrantly activated in various pediatric tumors. We conducted a phase I study of the Akt inhibitor perifosine in patients with recurrent/refractory pediatric CNS and solid tumors. This was a standard 3+3 open-l
Autor:
Hannah K. Lederman, Shahin Rafii, Rosandra N. Kaplan, Stefano Rivella, Stephen B. Doty, Dimitris Skokos, April S. Chan, Kristian Jensen, David Lyden
Publikováno v:
PLoS ONE, Vol 4, Iss 11, p e7955 (2009)
PLoS ONE
PLoS ONE
Background The bone-bone marrow interface is an area of the bone marrow microenvironment in which both bone remodeling cells, osteoblasts and osteoclasts, and hematopoietic cells are anatomically juxtaposed. The close proximity of these cells natural
Autor:
Marjan Berishaj, Jacqueline Bromberg, Kenneth Leslie, Kevin G. Mark, Agnes Viale, Jennifer Nnoli, David Lyden, Janeen Azare, William L. Gerald, Ashley S. Doane, Qing Chang, Mary L. Stracke, Maryam Hassimi, Hikmat Al-Ahmadie
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27851 (2011)
PLoS ONE
PLoS ONE
We determined that signal transducer and activator of transcription 3 (Stat3) is tyrosine phosphorylated in 37% of primary breast tumors and 63% of paired metastatic axillary lymph nodes. Examination of the distribution of tyrosine phosphorylated (pS