Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Dajiang. J. Liu"'
Publikováno v:
PLoS ONE, Vol 14, Iss 12, p e0226821 (2019)
The homeostatic iron regulator protein HFE is involved in regulation of iron acquisition for cells. The prevalence of two common HFE gene variants (H63D, C282Y) has been studied in many cancer types; however, the impact of HFE variants, sex and HFE g
Externí odkaz:
https://doaj.org/article/03bb4febe5094600bfdb02f21fd01a7c
Autor:
Yu Jiang, Sai Chen, Daniel McGuire, Fang Chen, Mengzhen Liu, William G Iacono, John K Hewitt, John E Hokanson, Kenneth Krauter, Markku Laakso, Kevin W Li, Sharon M Lutz, Matthew McGue, Anita Pandit, Gregory J M Zajac, Michael Boehnke, Goncalo R Abecasis, Scott I Vrieze, Xiaowei Zhan, Bibo Jiang, Dajiang J Liu
Publikováno v:
PLoS Genetics, Vol 14, Iss 7, p e1007452 (2018)
Meta-analysis of genetic association studies increases sample size and the power for mapping complex traits. Existing methods are mostly developed for datasets without missing values, i.e. the summary association statistics are measured for all varia
Externí odkaz:
https://doaj.org/article/762a0578df2243d88a5dccac238c0585
Autor:
Sang Y Lee, Junjia Zhu, Anna C Salzberg, Bo Zhang, Dajiang J Liu, Joshua E Muscat, Sara T Langan, James R Connor
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0174778 (2017)
Human hemochromatosis protein (HFE) is involved in iron metabolism. Two major HFE polymorphisms, H63D and C282Y, have been associated with an increased risk of cancers. Previously, we reported decreased gender effects in overall survival based on H63
Externí odkaz:
https://doaj.org/article/7ece441f657241b2ae2833a6b7a9a391
Autor:
Dajiang J Liu, Suzanne M Leal
Publikováno v:
PLoS Genetics, Vol 8, Iss 11, p e1003075 (2012)
Next-generation sequencing has made possible the detection of rare variant (RV) associations with quantitative traits (QT). Due to high sequencing cost, many studies can only sequence a modest number of selected samples with extreme QT. Therefore ass
Externí odkaz:
https://doaj.org/article/1331a04f68264df983ccf1969aa9a912
Autor:
Dajiang J Liu, Suzanne M Leal
Publikováno v:
PLoS Genetics, Vol 6, Iss 10, p e1001156 (2010)
There is solid evidence that rare variants contribute to complex disease etiology. Next-generation sequencing technologies make it possible to uncover rare variants within candidate genes, exomes, and genomes. Working in a novel framework, the kernel
Externí odkaz:
https://doaj.org/article/ea42db3c6847422a8ebe704ce5ecc40d
Publikováno v:
PLoS ONE, Vol 14, Iss 12, p e0226821 (2019)
PLoS ONE
PLoS ONE
The homeostatic iron regulator protein HFE is involved in regulation of iron acquisition for cells. The prevalence of two common HFE gene variants (H63D, C282Y) has been studied in many cancer types; however, the impact of HFE variants, sex and HFE g
Autor:
John K. Hewitt, Anita Pandit, Matt McGue, Michael Boehnke, John E. Hokanson, Sharon M. Lutz, Scott I. Vrieze, Xiaowei Zhan, Kenneth Krauter, Gonçalo R. Abecasis, Dajiang J. Liu, William G. Iacono, Kevin Li, Sai Chen, Fang Chen, Daniel McGuire, Mengzhen Liu, Gregory J.M. Zajac, Bibo Jiang, Yu Jiang, Markku Laakso
Publikováno v:
PLoS Genetics, Vol 14, Iss 7, p e1007452 (2018)
PLoS Genetics
PLoS Genetics
Meta-analysis of genetic association studies increases sample size and the power for mapping complex traits. Existing methods are mostly developed for datasets without missing values, i.e. the summary association statistics are measured for all varia
Autor:
Suzanne M. Leal, Dajiang J. Liu
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 6, Iss 10, p e1001156 (2010)
PLoS Genetics, Vol 6, Iss 10, p e1001156 (2010)
There is solid evidence that rare variants contribute to complex disease etiology. Next-generation sequencing technologies make it possible to uncover rare variants within candidate genes, exomes, and genomes. Working in a novel framework, the kernel