Zobrazeno 1 - 10
of 226
pro vyhledávání: '"BOYLE, P. A."'
Autor:
Lakshmipuram S Swapna, Grant C Stevens, Aline Sardinha-Silva, Lucas Zhongming Hu, Verena Brand, Daniel D Fusca, Cuihong Wan, Xuejian Xiong, Jon P Boyle, Michael E Grigg, Andrew Emili, John Parkinson
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 6, p e1012208 (2024)
The apicomplexan intracellular parasite Toxoplasma gondii is a major food borne pathogen that is highly prevalent in the global population. The majority of the T. gondii proteome remains uncharacterized and the organization of proteins into complexes
Externí odkaz:
https://doaj.org/article/11ae976dae7244d4a0d7a0915eb35d36
Publikováno v:
PLoS Genetics, Vol 20, Iss 5, p e1011277 (2024)
How enhancers regulate their target genes in the context of 3D chromatin organization is extensively studied and models which do not require direct enhancer-promoter contact have recently emerged. Here, we use the activation of estrogen receptor-depe
Externí odkaz:
https://doaj.org/article/387f06a75f744698b89a409bd7dfbca0
Publikováno v:
PLoS ONE, Vol 19, Iss 7, p e0306265 (2024)
BackgroundPerinatal depression (PND) is underdiagnosed in the clinical setting. This study explores the role of obstetricians, and other primary care providers of maternal and child healthcare in detecting, screening, and referring women during the p
Externí odkaz:
https://doaj.org/article/3449c35922fd4af8a29d8be06e8ecbd4
Autor:
Ana Paula Serafini Poeta Silva, Guilherme Arruda Cezar, Edison Sousa Magalhães, Kinath Rupasinghe, Srijita Chandra, Gustavo S Silva, Marcelo Almeida, Bret Crim, Eric Burrough, Phillip Gauger, Christopher Siepker, Marta Mainenti, Michael Zeller, Rodger G Main, Mary Thurn, Paulo Fioravante, Cesar Corzo, Albert Rovira, Hemant Naikare, Rob McGaughey, Franco Matias Ferreyra, Jamie Retallick, Jordan Gebhardt, Angela Pillatzki, Jon Greseth, Darren Kersey, Travis Clement, Jane Christopher-Hennings, Melanie Prarat, Ashley Johnson, Dennis Summers, Craig Bowen, Kenitra Hendrix, Joseph Boyle, Daniel Correia Lima Linhares, Giovani Trevisan
Publikováno v:
PLoS ONE, Vol 19, Iss 7, p e0306532 (2024)
This study evaluated the use of endemic enteric coronaviruses polymerase chain reaction (PCR)-negative testing results as an alternative approach to detect the emergence of animal health threats with similar clinical diseases presentation. This retro
Externí odkaz:
https://doaj.org/article/cec95462eb564034a375ac63fb2c688d
Publikováno v:
PLoS ONE, Vol 19, Iss 6, p e0305000 (2024)
Human sirtuin-2 (SIRT2) has emerged as an attractive drug target for a variety of diseases. The enzyme is a deacylase that can remove chemically different acyl modifications from protein lysine residues. Here, we developed a high-throughput screen ba
Externí odkaz:
https://doaj.org/article/6e526ce8626a4e829fdb4cf59c96d247
Publikováno v:
PLoS ONE, Vol 19, Iss 6 (2024)
Externí odkaz:
https://doaj.org/article/1e10b80fcee5426486921d662955fe6e
Autor:
Lucy Dipper, Niamh Devane, Rachel Barnard, Nicola Botting, Mary Boyle, Lin Cockayne, Deborah Hersh, Carla Magdalani, Jane Marshall, Kate Swinburn, Madeline Cruice
Publikováno v:
PLoS ONE, Vol 19, Iss 6, p e0304385 (2024)
BackgroundStroke survivors with aphasia want to improve their everyday talking (discourse). In current UK practice, 90% of speech and language therapists believe discourse assessment and treatment is part of their role but are hampered by barriers in
Externí odkaz:
https://doaj.org/article/c3eb34e3da154040804df5dfc228dbbb
Autor:
Hyeonjeong Lee, Camilla R L Machado, Deepa Hammaker, Eunice Choi, Edward B Prideaux, Wei Wang, David L Boyle, Gary S Firestein
Publikováno v:
PLoS ONE, Vol 19, Iss 6, p e0304530 (2024)
Rheumatoid arthritis (RA) is a systemic immune-mediated disease characterized by joint inflammation and destruction. The disease typically affects small joints in the hands and feet, later progressing to involve larger joints such as the knees, shoul
Externí odkaz:
https://doaj.org/article/2b85a7c05bcd4e318c6f0ff23d6ac2bb
Autor:
Hyeonjeong Lee, Camilla R. L. Machado, Deepa Hammaker, Eunice Choi, Edward B. Prideaux, Wei Wang, David L. Boyle, Gary S. Firestein
Publikováno v:
PLoS ONE, Vol 19, Iss 6 (2024)
Externí odkaz:
https://doaj.org/article/7ab07a9bfdbd436bb00e3288b40e40f5
Autor:
Sarah E. Philo, Nicolette A. Zhou, Lorraine M. Lillis, Venkata Raghava, Dilip Abraham, Vinoth Kumar, Nirmal Kumar, Jonathan Rigby, Joanna Ciol Harrison, Christine S. Fagnant-Sperati, Alexandra L. Kossik, Angelo Q. W. Ong, Rachael Swanstrom, Elisabeth Burnor, Bethel Demeke, Nicola K. Beck, Jeffry H. Shirai, Stephen J. Libby, David S. Boyle, Nicholas Feasey, Gagandeep Kang, John Scott Meschke
Publikováno v:
PLoS ONE, Vol 19, Iss 5 (2024)
Externí odkaz:
https://doaj.org/article/3cb0d247f348490680866a57895e2233