Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Alfredo Castello"'
Autor:
Andrew E Shaw, Suzannah J Rihn, Nardus Mollentze, Arthur Wickenhagen, Douglas G Stewart, Richard J Orton, Srikeerthana Kuchi, Siddharth Bakshi, Mila Rodriguez Collados, Matthew L Turnbull, Joseph Busby, Quan Gu, Katherine Smollett, Connor G G Bamford, Elena Sugrue, Paul C D Johnson, Ana Filipe Da Silva, Alfredo Castello, Daniel G Streicker, David L Robertson, Massimo Palmarini, Sam J Wilson
Publikováno v:
PLoS Biology, Vol 19, Iss 9, p e3001352 (2021)
Antiviral defenses can sense viral RNAs and mediate their destruction. This presents a challenge for host cells since they must destroy viral RNAs while sparing the host mRNAs that encode antiviral effectors. Here, we show that highly upregulated int
Externí odkaz:
https://doaj.org/article/93c6a324bb0649b4bf2748908f349e90
Autor:
Alfredo Castello, María Ángeles Muñoz-Fernández, Iván Ventoso, Javier del Pino, Jose L. Jimenez, Juan José Berlanga, César de Haro
Publikováno v:
Biblos-e Archivo. Repositorio Institucional de la UAM
instname
PLoS ONE, Vol 7, Iss 10, p e47272 (2012)
Digital.CSIC. Repositorio Institucional del CSIC
PLoS ONE
instname
PLoS ONE, Vol 7, Iss 10, p e47272 (2012)
Digital.CSIC. Repositorio Institucional del CSIC
PLoS ONE
The reversible phosphorylation of the alpha-subunit of eukaryotic translation initiation factor 2 (eIF2alpha) is a well-characterized mechanism of translational control in response to a wide variety of cellular stresses, including viral infection. Be
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e73723 (2013)
Poliovirus protease 2A (2A(pro)) obstructs host gene expression by reprogramming transcriptional and post-transcriptional regulatory events during infection. Here we demonstrate that expression of 2A(pro) induces a selective nucleo-cytoplasm transloc
Externí odkaz:
https://doaj.org/article/387285fad23c43fda3c4bd290de87586
Autor:
Javier del Pino, José Luis Jiménez, Iván Ventoso, Alfredo Castelló, Ma Ángeles Muñoz-Fernández, César de Haro, Juan José Berlanga
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e47272 (2012)
The reversible phosphorylation of the alpha-subunit of eukaryotic translation initiation factor 2 (eIF2alpha) is a well-characterized mechanism of translational control in response to a wide variety of cellular stresses, including viral infection. Be
Externí odkaz:
https://doaj.org/article/3dad714f473849a4a52310c241437ed1
Autor:
Alfredo Castelló, David Franco, Pablo Moral-López, Juan J Berlanga, Enrique Alvarez, Eckard Wimmer, Luis Carrasco
Publikováno v:
PLoS ONE, Vol 4, Iss 11, p e7997 (2009)
A number of viral proteases are able to cleave translation initiation factors leading to the inhibition of cellular translation. This is the case of human immunodeficiency virus type 1 protease (HIV-1 PR), which hydrolyzes eIF4GI and poly(A)-binding
Externí odkaz:
https://doaj.org/article/7b908a151b204eba98257ae5ecdac5c6
Autor:
Alfredo Castelló, Ana Quintas, Elena G Sánchez, Prado Sabina, Marisa Nogal, Luis Carrasco, Yolanda Revilla
Publikováno v:
PLoS Pathogens, Vol 5, Iss 8, p e1000562 (2009)
African swine fever virus (ASFV), like other complex DNA viruses, deploys a variety of strategies to evade the host's defence systems, such as inflammatory and immune responses and cell death. Here, we analyse the modifications in the translational m
Externí odkaz:
https://doaj.org/article/1eccfe20a4524406b36cd718b5fdb1df
Publikováno v:
PLoS ONE, Vol 4, Iss 3, p e4772 (2009)
Infection of BHK cells by Sindbis virus (SV) gives rise to a profound inhibition of cellular protein synthesis, whereas translation of viral subgenomic mRNA that encodes viral structural proteins, continues for hours. To gain further knowledge on the
Externí odkaz:
https://doaj.org/article/748bd5c008c44ef08706d76446a7f9d6