Zobrazeno 1 - 10
of 202
pro vyhledávání: '"63"'
Autor:
Guozhi Jiang, Andrea O Luk, Claudia H T Tam, Eric S Lau, Risa Ozaki, Elaine Y K Chow, Alice P S Kong, Cadmon K P Lim, Ka Fai Lee, Shing Chung Siu, Grace Hui, Chiu Chi Tsang, Kam Piu Lau, Jenny Y Y Leung, Man-Wo Tsang, Grace Kam, Ip Tim Lau, June K Li, Vincent T Yeung, Emmy Lau, Stanley Lo, Samuel K S Fung, Yuk Lun Cheng, Chun Chung Chow, Ewan R Pearson, Wing Yee So, Juliana C N Chan, Ronald C W Ma, Hong Kong Diabetes Register TRS Study Group, Hong Kong Diabetes Biobank Study Group
Publikováno v:
PLoS Medicine, Vol 17, Iss 7, p e1003209 (2020)
PLoS Medicine
PLoS Medicine
Background Type 2 diabetes (T2D) is a progressive disease whereby there is often deterioration in glucose control despite escalation in treatment. There is significant heterogeneity to this progression of glycemia after onset of diabetes, yet the fac
Autor:
Yoon Jin Cha, Chang Ik Yoon, Joon Jeong, Hak Woo Lee, Sung Gwe Ahn, Seung Ah Lee, Soong June Bae
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0187679 (2017)
PLoS ONE
PLoS ONE
Aim The 21-gene recurrence score (RS) predicts a clinical benefit of chemotherapy for individuals with ER-positive/HER2-negative breast cancer. Using in vitro chemoresponse assay, we compared the chemosensitivity according to RS in these patients. Me
Autor:
Robert Tibshirani, Livia S. Eberlin, Ivette Planell-Mendez, Katherine Margulis, Teri A. Longacre, Richard N. Zare, George A. Poultsides, Moe Jalali, Jeffrey A. Norton
Publikováno v:
PLoS Medicine, Vol 13, Iss 8, p e1002108 (2016)
PLoS Medicine
PLoS Medicine, Public Library of Science, 2016, 13 (8), ⟨10.1371/journal.pmed.1002108⟩
PLoS Medicine
PLoS Medicine, Public Library of Science, 2016, 13 (8), ⟨10.1371/journal.pmed.1002108⟩
Background Surgical resection with microscopically negative margins remains the main curative option for pancreatic cancer; however, in practice intraoperative delineation of resection margins is challenging. Ambient mass spectrometry imaging has eme
Autor:
Xiaosi Han, Paula Warren, Louis B. Nabors, Andrew DeAtkine, John B. Fiveash, Elias Khayat, Hassan M. Fathallah-Shaykh, Asim K. Bag, Nidhal Bouaynaya, James M. Markert, Elizabeth Coffee, Markus Bredel
Publikováno v:
PLoS Medicine, Vol 16, Iss 5, p e1002810 (2019)
PLoS Medicine
PLoS Medicine
Background Low-grade gliomas cause significant neurological morbidity by brain invasion. There is no universally accepted objective technique available for detection of enlargement of low-grade gliomas in the clinical setting; subjective evaluation b
Autor:
Paola Mencarini, Silvia Murachelli, Maria Musso, Delia Goletti, Assunta Navarra, Laura Santangelo, Antonino Di Caro, Silvia Mosti, Fabrizio Palmieri, Gina Gualano, Angela Cannas, Enrico Girardi
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 2, p e0212948 (2019)
PLoS ONE, Vol 14, Iss 2, p e0212948 (2019)
RationaleTreatment of multi-drug resistant Tuberculosis (MDR-TB) is challenging because it mostly relies on drugs with lower efficacy and greater toxicity than those used for drug-susceptible TB.ObjectivesAim of the study was to describe the frequenc
Publikováno v:
PLoS Biology
PLoS Biology, Vol 16, Iss 12, p e3000091 (2018)
PLoS Biology, Vol 16, Iss 12, p e3000091 (2018)
Nonalcoholic fatty liver disease (NAFLD) is characterized by abnormal accumulation of triglycerides (TG) in the liver and other metabolic syndrome symptoms, but its molecular genetic causes are not completely understood. Here, we show that mice defic
Autor:
Yitao Zhang, Jiaojie Xue, Yi-Zhan Guo, Shiyao Cheng, Kanglin Cheng, Zhi-Chong Chen, Weijie Zeng, Qing Wang, Mao-De Ou
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0157171 (2016)
PLoS ONE
PLoS ONE
Background Pulmonary hypertension due to left heart disease (PH-LHD) is one of the most common forms of PH, termed group 2 PH. Atorvastatin exerts beneficial effects on the structural remodeling of the lung in ischemic heart failure. However, few stu
Autor:
Julie M. Skinner, Xiangjun Meng, Shubing Wang, Jon Heinrichs, Melissa A. Boddicker, Catherine D. G. Hines, Jeffrey G. Smith
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0160055 (2016)
PLoS ONE
PLoS ONE
Chlamydia trachomatis is among the most prevalent of sexually transmitted diseases. While Chlamydia infection is a reportable event and screening has increased over time, enhanced surveillance has not resulted in a reduction in the rate of infections
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0197252 (2018)
PLoS ONE
PLoS ONE
Purpose Intermittent androgen deprivation therapy is an effective treatment for metastatic prostate cancer. However, no study to date has evaluated the long-term outcomes of this treatment among patients with prostate cancer after radical prostatecto
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132610 (2015)
PLoS ONE
PLoS ONE
Primary ovarian insufficiency (POI), also known as premature ovarian failure (POF), is defined as more than six months of cessation of menses before the age of 40 years, with two serum follicle stimulating hormone (FSH) levels (at least 1 month apart