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Autor:
Uri Alon, Omer Karin
Funder: James S. McDonnell Foundation 21st Century Science Initiative Understanding Dynamic
Funder: Multi-scale Systems - Postdoctoral Fellowship Award
Studying the brain circuits that control behavior is challenging, since in addition to t
Funder: Multi-scale Systems - Postdoctoral Fellowship Award
Studying the brain circuits that control behavior is challenging, since in addition to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::656c1af89a79d8a916934e0287a42a50
https://www.repository.cam.ac.uk/handle/1810/339845
https://www.repository.cam.ac.uk/handle/1810/339845
Autor:
Yusuke Ichiyama, Masashi Kakinoki, Shumpei Obata, Yoshitsugu Saishin, Osamu Sawada, Riko Matsumoto, Masahito Ohji, Tomoko Sawada
Publikováno v:
PLOS ONE. 17:e0278951
Purpose:To assess the interaction between ranibizumab, aflibercept, and mouse vascular endothelial growth factor (VEGF), both in vivo and in vitro.
Methods:In vivo, the effect of intravitreal injection of ranibizumab and aflibercept on oxygen in
Methods:In vivo, the effect of intravitreal injection of ranibizumab and aflibercept on oxygen in
Autor:
Ferdia A. Gallagher, Wendi Qian, Fulvio Zaccagna, Stephan Ursprung, Grant D. Stewart, Anne Y. Warren, Sarah J. Welsh, Tristan Barrett, Timothy Eisen, Andrew N. Priest, Andrea Machin
Publikováno v:
PLoS ONE, Vol 16, Iss 10 (2021)
PLoS ONE
PLoS ONE, Vol 16, Iss 10, p e0258988 (2021)
PLoS ONE
PLoS ONE, Vol 16, Iss 10, p e0258988 (2021)
Funder: NIHR Cambridge Biomedical Research Centre
Funder: Addenbrooke’s Charitable Trust
Funder: National Institute for Health Research (NIHR)
Funder: Mark Foundation For Cancer Research
Funder: Cambridge Commonwealth, European
Funder: Addenbrooke’s Charitable Trust
Funder: National Institute for Health Research (NIHR)
Funder: Mark Foundation For Cancer Research
Funder: Cambridge Commonwealth, European
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::175576bf7192b19e2d8f1d92a44d8c2e
Autor:
Sven Peine, Marissa Herrmann, Hendrik Karsten, Marc Lütgehetmann, Matthias Marget, Matin Kohsar, William W. Kwok, John Sidney, Janna Heide, Sophia Schulte, Alessandro Sette, Julian Schulze zur Wiesch, Alexandra M. Johansson, Thomas Theo Brehm
Publikováno v:
PLoS Pathogens, Vol 18, Iss 1 (2022)
PLoS Pathogens, Vol 17, Iss 9, p e1009842 (2021)
PLoS Pathogens
PLoS Pathogens, Vol 18, Iss 1, p e1010220 (2022)
PLoS Pathogens, Vol 17, Iss 9, p e1009842 (2021)
PLoS Pathogens
PLoS Pathogens, Vol 18, Iss 1, p e1010220 (2022)
The aim of this study was to define the breadth and specificity of dominant SARS-CoV-2-specific T cell epitopes using a comprehensive set of 135 overlapping 15-mer peptides covering the SARS-CoV-2 envelope (E), membrane (M) and nucleoprotein (N) in a
Serum miR-192-5p levels predict the efficacy of pegylated interferon therapy for chronic hepatitis B
Autor:
Hiroki Ikeda, Akihiro Matsumoto, Masataka Tsuge, Takako Inoue, Masakuni Tateyama, Kentaro Matsuura, Tsunamasa Watanabe, Masanori Atsukawa, Eiji Tanaka, Takeshi Matsui, Masaru Enomoto, Yasuhito Tanaka, Shuhei Nishiguchi, Jong-Hon Kang, Chiaki Okuse, Yoshihito Nagura, Hiromi Kataoka, Etsuko Iio, Koji Fujita
Publikováno v:
PLoS ONE, Vol 17, Iss 2 (2022)
PLoS ONE, Vol 17, Iss 2, p e0263844 (2022)
PLoS ONE, Vol 17, Iss 2, p e0263844 (2022)
We examined the association between serum miRNA (-192-5p, -122-3p, -320a and -6126-5p) levels and the efficacy of pegylated interferon (Peg-IFN) monotherapy for chronic hepatitis B (CHB) patients. We enrolled 61 CHB patients treated with Peg-IFNα-2a
Autor:
M. S. R. Khan, Md. Tanvir Rahman, Mohammed A. Samad, Md. Abdul Kafi, Nure Alam Siddiky, M. S. Sarker
Publikováno v:
PLoS ONE, Vol 17, Iss 2, p e0254465 (2022)
PLoS ONE
PLoS ONE
The rapid emergence of virulent and multidrug-resistant (MDR) non-typhoidal Salmonella (NTS) enterica serovars are a growing public health concern globally. The present study focused on the assessment of the pathogenicity and antimicrobial resistance
Publikováno v:
PLoS Genetics, Vol 17, Iss 12, p e1009938 (2021)
PLoS Genetics
PLoS Genetics
Choline is an essential component of Acetylcholine (ACh) biosynthesis pathway which requires high-affinity Choline transporter (ChT) for its uptake into the presynaptic terminals of cholinergic neurons. Previously, we had reported a predominant expre
Autor:
Therese Sheppard, Usman Iqbal, Robyn Tamblyn, Jack Shiansong Li, David L. Buckeridge, Meghna Jani, Shelly A. Vik, David W. Bates, Colin Weaver, Nadyne Girard, William G Dixon, Judy E. Seidel
Publikováno v:
PLoS Medicine, Vol 18, Iss 11 (2021)
Jani, M, Girard, N, Bates, D, Buckeridge, D, Sheppard, T, Li, J S, Iqbal, U, Vik, S, Weaver, C, Seidel, J, Dixon, W & Tamblyn, R 2021, ' Opioid prescribing among new users for non-cancer pain in USA, Canada, UK and Taiwan : a population-based cohort study ', PL o S Medicine, vol. 18, no. 11, e1003829, pp. 1-15 . https://doi.org/10.1371/journal.pmed.1003829
PLoS Medicine
PLoS Medicine, Vol 18, Iss 11, p e1003829 (2021)
Jani, M, Girard, N, Bates, D, Buckeridge, D, Sheppard, T, Li, J S, Iqbal, U, Vik, S, Weaver, C, Seidel, J, Dixon, W & Tamblyn, R 2021, ' Opioid prescribing among new users for non-cancer pain in USA, Canada, UK and Taiwan : a population-based cohort study ', PL o S Medicine, vol. 18, no. 11, e1003829, pp. 1-15 . https://doi.org/10.1371/journal.pmed.1003829
PLoS Medicine
PLoS Medicine, Vol 18, Iss 11, p e1003829 (2021)
Background The opioid epidemic in North America has been driven by an increase in the use and potency of prescription opioids, with ensuing excessive opioid-related deaths. Internationally, there are lower rates of opioid-related mortality, possibly
Autor:
Sylvain Mutanda, Medard Ilunga, Olaf Valverde Mordt, Digas Ngolo Tete, Wilfried Mutombo, Caecilia Schmid, Victor Kande, Séverine Blesson, Andrea Kuemmerle, Ismael Lumpungu, Christian Burri, Mays Kisala, Sonja Bernhard, Pathou Nganzobo
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 11, p e0009903 (2021)
PLoS Neglected Tropical Diseases, Vol 15, Iss 11 (2021)
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 15, Iss 11 (2021)
PLoS Neglected Tropical Diseases
Background Nifurtimox-eflornithine combination therapy (NECT) for the treatment of second stage gambiense human African trypanosomiasis (HAT) was added to the World Health Organization’s Essential Medicines List in 2009 after demonstration of its n
Autor:
Louis Scampavia, Claudia M. Rohr, Timothy P. Spicer, Evgeny G. Chulkov, Sang-Kyu Park, Jonathan S. Marchant, Emery Smith, Nawal A. Yahya
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 11 (2021)
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 15, Iss 11, p e0009898 (2021)
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 15, Iss 11, p e0009898 (2021)
Given the worldwide burden of neglected tropical diseases, there is ongoing need to develop novel anthelmintic agents to strengthen the pipeline of drugs to combat these burdensome infections. Many diseases caused by parasitic flatworms are treated u