Zobrazeno 1 - 10
of 10
pro vyhledávání: '"63"'
Autor:
Zhi-Dong Ge, Paul S. Pagel, Deron W. Jones, Hao Xu, Dorothee Weihrauch, John G. Krolikowski, Kirkwood A. Pritchard
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52046 (2012)
PLoS ONE
PLoS ONE
The apoAI mimetic 4F was designed to inhibit atherosclerosis by improving HDL. We reported that treating tight skin (Tsk(-/+)) mice, a model of systemic sclerosis (SSc), with 4F decreases inflammation and restores angiogenic potential in Tsk(-/+) hea
Autor:
Sung Keun Kang, Byung Il Yoon, Eun Jung Park, Hyun Ju Oh, Byeong Chun Lee, Geon A Kim, Jung-Eun Park, Goo Jang, Young Kwang Jo, Sang Hyun Lim, Jin Choi, Min Jung Kim
Publikováno v:
PLOS ONE(9): 11
PLoS ONE
PLoS ONE, Vol 9, Iss 11, p e108330 (2014)
PLoS ONE
PLoS ONE, Vol 9, Iss 11, p e108330 (2014)
Whereas it has been assumed that genetically modified tissues or cells derived from somatic cell nuclear transfer (SCNT) should be accepted by a host of the same species, their immune compatibility has not been extensively explored. To identify accep
Autor:
Matthew J. Burton, Hassan Joof, Sarah E. Burr, Chrissy h. Roberts, David Mabey, Pateh Makalo, Tamsyn Derrick, Megha Rajasekhar, Martin J. Holland, Robin L. Bailey
Publikováno v:
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 7, Iss 3, p e2117 (2013)
PLoS Neglected Tropical Diseases, Vol 7, Iss 3, p e2117 (2013)
Purpose Trachoma is a fibrotic disease of the conjunctiva initiated by Chlamydia trachomatis infection. This blinding disease affects over 40 million people worldwide yet the mechanisms underlying its pathogenesis remain poorly understood. We have in
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e70552 (2013)
PLoS ONE
PLoS ONE
Background: Human rhinoviruses (HRV) are associated with upper and lower respiratory illnesses, including severe infections causing hospitalization in both children and adults. Although the clinical significance of HRV infections is now well establis
Autor:
Bernard N. Kanoi, Adoke Yeka, Betty Balikagala, Shigeharu Ueda, Kohhei Tetsutani, Nahoko Suzuki, Christopher Nsereko, Masanori Yagi, Nobuko Arisue, Kazuya Ito, Hiroki Shirai, Nirianne Marie Q. Palacpac, Takahiro Tougan, Yoshio Hirota, Takuya Okada, Wakaba Fukushima, Toshihiro Horii, Thomas G. Egwang, Sawako Itagaki, Ken Ishii, Edward H. Ntege
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64073 (2013)
PLoS ONE
PLoS ONE
Background Up to now a malaria vaccine remains elusive. The Plasmodium falciparum serine repeat antigen-5 formulated with aluminum hydroxyl gel (BK-SE36) is a blood-stage malaria vaccine candidate that has undergone phase 1a trial in malaria-naive Ja
Autor:
Britta C. Urban, Ya Jankey Jagne, Katherine Gantlett, Kalifa Bojang, Carly M. Bliss, Miguel A. Garcia Knight, Peninah Soipei, Riccardo Cortese, Nicola K. Viebig, Eva N Kimani, Susanne H. Sheehy, Katharine A. Collins, Alison M. Lawrie, Alexandra J. Spencer, Joseph Okebe, Alfredo Nicosia, Philip Bejon, Caroline Ogwang, Domtila Kimani, Egeruan B. Imoukhuede, Rachel Roberts, Eleanor Berrie, Jenny Mueller, Muhammed O. Afolabi, Stefano Colloca, Sarah Moyle, Adrian V. S. Hill, Sarah C. Gilbert, Nicholas A. Anagnostou, Katie L. Flanagan, Katie J. Ewer, Christopher J A Duncan, Roma Chilengi
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e57726 (2013)
PLoS ONE
PLoS ONE
BACKGROUND: Heterologous prime boost immunization with chimpanzee adenovirus 63 (ChAd63) and Modified vaccinia Virus Ankara (MVA) vectored vaccines is a strategy recently shown to be capable of inducing strong cell mediated responses against several
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e25130 (2011)
PLoS ONE
PLoS ONE
Background Passively acquired maternal antibodies in infants may inhibit active immune responses to vaccines. Whether maternal antibody against hepatitis B surface antigen (anti-HBs) in infants may influence the long-term immunogenicity of hepatitis
Autor:
Celia L. McNeilly, Adrian V. S. Hill, Sarah C. Gilbert, Sally R. Yukiko, Frances E. Pearson, Michael L. Crichton, Xianfeng Chen, Germain J. P. Fernando, Mark A. F. Kendall, Clare A. Primiero
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e67888 (2013)
PLoS ONE
PLoS ONE
The disadvantages of needle-based immunisation motivate the development of simple, low cost, needle-free alternatives. Vaccine delivery to cutaneous environments rich in specialised antigen-presenting cells using microprojection patches has practical
Autor:
Serge Amselem, Katia Stankovic Stojanovic, Philippe Duquesnoy, Sonia Karabina, Emmanuel Grimprel, Emmanuelle Cochet, Véronique Hentgen, Gilles Grateau, Gaëlle Le Borgne, Isabelle Jéru
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68431 (2013)
PLoS ONE
PLoS ONE, 2013, 8 (7), pp.e68431. ⟨10.1371/journal.pone.0068431⟩
PLoS ONE
PLoS ONE, 2013, 8 (7), pp.e68431. ⟨10.1371/journal.pone.0068431⟩
International audience; Background: Familial Mediterranean fever (FMF) is an autosomal recessive autoinflammatory disorder due to MEFV mutations and one of the most frequent Mediterranean genetic diseases. The observation of many heterozygous patient
Autor:
Dominique Salmon, Christine Durier, Corinne Guérin, Mathieu Surenaud, Jean-Gérard Guillet, Hanne Gahery, Bénédicte Bonnet, Gilles Pialoux, Isabelle Bourgault Villada, Nadine Ben Hamouda, Gustavo Gonzalez-Canali, Angela Jackson, Lise Cuzin, Suzanne Figuereido, Corinne Desaint, Benjamin Silbermann, Jeannine Choppin, Isabelle Poizot-Martin, Odile Launay
Publikováno v:
PLoS ONE, Vol 2, Iss 8, p e725 (2007)
PLoS ONE
PLoS ONE
Objective The objective was to compare the safety and cellular immunogenicity of intradermal versus intramuscular immunization with an HIV-lipopeptide candidate vaccine (LIPO-4) in healthy volunteers. Methodology A randomized, open-label trial with 2