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pro vyhledávání: ''
Autor:
Montserrat Esteve, Joana Pérez de San Román, Felix Junyent, María J. Ramírez, Grasa Mm, Angelo Ledda, Francisco J. Gil-Bea, José Gulfo
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
PLoS ONE
PLoS ONE, Vol 16, Iss 2, p e0246930 (2021)
Universidad de Barcelona
PLoS ONE
PLoS ONE, Vol 16, Iss 2, p e0246930 (2021)
Corticosteroid-binding globulin (CBG) is the specific carrier of circulating glucocorticoids, but evidence suggests that it also plays an active role in modulating tissue glucocorticoid activity. CBG polymorphisms affecting its expression or affinity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daa6b1310837c928c1c27d4dc46919cf
http://hdl.handle.net/2445/175036
http://hdl.handle.net/2445/175036
Autor:
Rachel E. Carlisle, Sarah Liu, Ming Chan Zhang, Chao Lu, Jeffrey G. Dickhout, Andy Phan, Elise Brimble, Salwa Farooqi
Publikováno v:
PLoS ONE, Vol 16, Iss 11, p e0260519 (2021)
PLoS ONE
PLoS ONE
Endoplasmic reticulum (ER) stress is associated with acute kidney injury (AKI) caused by various mechanisms, including antibiotics, non-steroidal anti-inflammatory drugs, cisplatin, and radiocontrast. Tunicamycin (TM) is a nucleoside antibiotic that
Autor:
Qiuju Huang, Zhongqiu Liu, Xiaoxiao Qi, Yanmin Zhang, Linlin Lu, Jiahao Chen, Ying Wang, Jian-Hua Deng, Jiada Han, Dawei Wang, Feng Qian, Elaine Lai-Han Leung
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0249276 (2021)
PLoS ONE
PLoS ONE
Aconitine (AC) is the primary bioactive and secondary metabolite alkaloidin of Aconitum species which is accounted for more than 60% of the total diester-diterpenoid alkaloids in Aconite. To evaluate the analgesic effects of AC, 4 different pain mode
Autor:
Alison Pan, Susanne M. Steggerda, Tony T. Huang, Tracy Y. Wang, Weiqun Li, Natalija Sotirovska, Matt Gross, Francesco Parlati, Devansh Singh, Jason J. Chen, Ethan Emberley, Andrew Mackinnon, Rosalyn Dang
Publikováno v:
PLoS ONE, Vol 16, Iss 11, p e0259241 (2021)
PLoS ONE
PLoS ONE, Vol 16, Iss 11 (2021)
PLoS ONE
PLoS ONE, Vol 16, Iss 11 (2021)
Dysregulated metabolism is a hallmark of cancer that manifests through alterations in bioenergetic and biosynthetic pathways to enable tumor cell proliferation and survival. Tumor cells exhibit high rates of glycolysis, a phenomenon known as the Warb
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0257012 (2021)
PLoS ONE
PLoS ONE
Sodium carboxymethyl starch (CMS-Na), a kind of food additive with high degree of substitution, is also known as a prebiotic. The aim of this study was to determine the effect of CMS-Na on defecation. Constipated mouse model was prepared by loperamid
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0239108 (2021)
PLoS ONE
PLoS ONE
Retinal inflammation accelerates photoreceptor cell death caused by retinal degeneration. Minocycline, a semisynthetic broad-spectrum tetracycline antibiotic, has been previously reported to rescue photoreceptor cell death in retinal degeneration. We
Autor:
Avril Coghlan, Helen Whiteland, Karl F. Hoffmann, Josephine Forde Thomas, Alessandra Crusco, Patrick J. Murphy, Jamie Tibble-Howlings, Lisa Wilhelmina Bloemberg
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 10, p e0008630 (2020)
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases
Background Schistosomiasis is a prevalent neglected tropical disease that affects approximately 300 million people worldwide. Its treatment is through a single class chemotherapy, praziquantel. Concerns surrounding the emergence of praziquantel insen
Publikováno v:
PLoS ONE, Vol 16, Iss 11, p e0260713 (2021)
PLoS ONE
PLoS ONE
Similar to psychostimulants, the peripheral administration of menthol promotes mouse motor activity, and the neurotransmitter dopamine has been suggested to be involved in this effect. The present study aimed to elucidate the effects of l-menthol on
Autor:
Fabio García-García, Gabriela López-Herrera, Héctor Romero-Ramírez, Amayrani Abrego-Peredo, Claudia Sandoval-Montes, Mónica Flores-Muñoz, Enrique Espinosa, Juan Carlos Rodríguez-Alba
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0233138 (2020)
PLoS ONE
PLoS ONE
Naringenin is flavonoid mainly found in citrus fruits which has shown several biological properties. In this work, we evaluated the therapeutic potential of the flavonoid Naringenin. Five-month-old B6.MRL-Faslpr/J lupus-prone mice were administered d
Autor:
Deniz A. Ucar, Elizabeth C. Martin, Bridgette M. Collins-Burow, Matthew E. Burow, Sukhmani Gill, Hope E. Burks, Adam I. Riker, Henri Wathieu, Lucio Miele, Steven Elliott, Bruce A. Bunnell, Margarite D. Matossian, Rachel A. Sabol, Luis Del Valle, Jovanny Zabaleta, Tiffany C. Chang
Publikováno v:
PLoS ONE, Vol 15, Iss 10, p e0226464 (2020)
PLoS ONE
PLoS ONE
Metaplastic breast carcinoma (MBC) is a clinically aggressive and rare subtype of breast cancer, with similar features to basal-like breast cancers. Due rapid growth rates and characteristic heterogeneity, MBC is often unresponsive to standard chemot