Zobrazeno 1 - 10
of 476
pro vyhledávání: ''
Publikováno v:
PLoS ONE, Vol 16, Iss 10, p e0258617 (2021)
PLoS ONE
Murni, I K, Sulistyoningrum, D C, Gasevic, D, Susilowati, R & Julia, M 2021, ' Sex differences in the association of vitamin D and metabolic risk factors with carotid intima-media thickness in obese adolescents ', PLoS ONE, vol. 16, no. 10, pp. e0258617 . https://doi.org/10.1371/journal.pone.0258617
PLoS ONE, Vol 16, Iss 10 (2021)
PLoS ONE
Murni, I K, Sulistyoningrum, D C, Gasevic, D, Susilowati, R & Julia, M 2021, ' Sex differences in the association of vitamin D and metabolic risk factors with carotid intima-media thickness in obese adolescents ', PLoS ONE, vol. 16, no. 10, pp. e0258617 . https://doi.org/10.1371/journal.pone.0258617
PLoS ONE, Vol 16, Iss 10 (2021)
Background It has been shown that vitamin D is associated with obesity and the development of atherosclerosis. Less is known about this association among adolescents with obesity. Objectives To determine the association of vitamin D level and metabol
Publikováno v:
PLoS ONE, Vol 16, Iss 8, p e0254590 (2021)
PLoS ONE
PLoS ONE
SUA is associated with cardiovascular disease and cardiovascular disease risk factors in adults, including chronic kidney disease, coronary artery disease, stroke, diabetes mellitus, preeclampsia, and hypertension. A cross-sectional study was carried
Autor:
Samuel Kwasi Appiah, Charles Nkansah, Kofi Boamah Mensah, Dorcas Serwaa, Alexander Yaw Debrah, Patrick Adu, Otchere Addai-Mensah, Richard K. D. Ephraim, Michael Owusu, Felix Osei-Boakye, Charles A. Derigubah
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0250090 (2021)
PLoS ONE
PLoS ONE
Background Hypofibrinolysis resulting from the up-regulation of plasminogen activator inhibitor-1 (PAI-1) usually occurs in patients with type 2 diabetes mellitus (T2DM), rendering them hypercoagulable. This study assessed the plasma antigen and acti
Autor:
Kristine Griffett, Amina Kameric, Monideepa Sengupta, Arindam Chatterjee, Aurore Cecile-Valfort, Suomia Abuirqeba, Thomas P. Burris, Colin A. Flaveny
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0249316 (2021)
PLoS ONE
PLoS ONE
Alcoholic liver disease (ALD) is responsible for an average of 50.4% and 44.2%of liver disease deaths among males and females respectively. Driven by alcohol misuse, ALD is often reversible by cessation of consumption. However, abstinence programs ca
Autor:
Seung Ju Kim, Kyu Tae Han
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0250716 (2021)
PLoS ONE
PLoS ONE
Introduction Colorectal cancer(CRC) is 3rd most common cancer and has a relatively high mortality rate. Currently, the relationships between CRC and serum cholesterol or statin treatment, especially in older adults under 75 years of age, remain quest
Autor:
Manuela Michenthaler, Gunter Almer, Richard Partl, Gernot Reishofer, Wilfried Renner, Eva Hassler, Alexander Staszewski, Hannes Deutschmann, Harald Mangge, Markus Herrmann, Stefan L Leber, Felix Gunzer
Publikováno v:
PLoS ONE, Vol 16, Iss 11, p e0259952 (2021)
PLoS ONE
PLoS ONE, Vol 16, Iss 11 (2021)
PLoS ONE
PLoS ONE, Vol 16, Iss 11 (2021)
Obesity and metabolic syndrome (MetS) are associated with hypoadiponectinemia. On the contrary, studies revealed correlations between the amount of subcutaneous adipose tissue (SAT) and higher serum adiponectin levels. Furthermore, independent associ
Autor:
Cleverson Teixeira Soares, Maria Ângela de Melo Marques, José Augusto da Costa Nery, Georgia C. Atella, Maria Cristina Vidal Pessolani, Carlos A.M. Silva, Prithwiraj De, Delphi Chatterjee, Maria Renata Sales Nogueira, Patrícia Sammarco Rosa, Cristiana Santos de Macedo, Robertha Mariana Rodrigues Lemes
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 3, p e0008138 (2020)
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases
The changes in host lipid metabolism during leprosy have been correlated to fatty acid alterations in serum and with high-density lipoprotein (HDL) dysfunctionality. This is most evident in multibacillary leprosy patients (Mb), who present an accumul
Autor:
Nicole Soranzo, Eleftheria Zeggini, Emanuele Di Angelantonio, Interval Study, Kousik Kundu, Adam S. Butterworth, Fernando Riveros-Mckay, Willem H. Ouwehand, Clare Oliver-Williams, Klaudia Walter, Inês Barroso, Eleanor Wheeler, John Danesh, Savita Karthikeyan, David J. Roberts
Publikováno v:
PLoS Genetics, Vol 16, Iss 3, p e1008605 (2020)
PLoS Genetics
PLoS Genet. 16:e1008605 (2020)
PLoS Genetics
PLoS Genet. 16:e1008605 (2020)
Circulating metabolite levels are biomarkers for cardiovascular disease (CVD). Here we studied, association of rare variants and 226 serum lipoproteins, lipids and amino acids in 7,142 (discovery plus follow-up) healthy participants. We leveraged the
Autor:
Tuomo Kiiskinen, Matthew J. Bown, Sekar Kathiresan, James G. Wilson, John Danesh, Heribert Schunkert, Krishna G. Aragam, Joshua C. Denny, Million Veteran Program, Diego Ardissino, Danish Saleheen, Marina Serper, Julie A. Lynch, Marijana Vujkovic, Usman Baber, Alexander G. Bick, George Hindy, Amit Khera, Nilesh J. Samani, Connor A. Emdin, Mark J. Daly, Hugh Watkins, Ruth McPherson, Aki S. Havulinna, QiPing Feng, Scott M. Damrauer, Namrata Gupta, Derek Klarin, Roberto Elosua, Juha Karjalainen, Philip S Tsao, B F Voight, Josep M. Mercader, Craig L. Hanis, Kyong-Mi Chang, Mark Chaffin, Wei-Qi Wei, David E. Kaplan, Stacey Gabriel, Lan Jiang, Jeanette Erdmann, Mary E. Haas
Publikováno v:
PLoS Genetics, Vol 16, Iss 4, p e1008629 (2020)
PLoS Genetics, Vol 17, Iss 4, p e1009503 (2021)
PLoS Genetics
PLoS Genetics, Vol 17, Iss 4, p e1009503 (2021)
PLoS Genetics
Analyzing 12,361 all-cause cirrhosis cases and 790,095 controls from eight cohorts, we identify a common missense variant in the Mitochondrial Amidoxime Reducing Component 1 gene (MARC1 p.A165T) that associates with protection from all-cause cirrhosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b2aeafb245632b250e5e05c8a2d99cd
http://hdl.handle.net/10230/47380
http://hdl.handle.net/10230/47380
Autor:
Signe Sloth Mogensen, Pernille Rudebeck Mogensen, Thomas Frandsen, Kathrine Grell, Allan Vaag, Ulrik Malthe Overgaard, Kjeld Schmiegelow, Benjamin Ole Wolthers
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0231209 (2020)
PLoS ONE
Mogensen, P R, Grell, K, Schmiegelow, K, Overgaard, U M, Wolthers, B O, Mogensen, S S, Vaag, A & Frandsen, T L 2020, ' Dyslipidemia at diagnosis of childhood acute lymphoblastic leukemia ', PLoS ONE, vol. 15, no. 4, e0231209 . https://doi.org/10.1371/journal.pone.0231209
PLoS ONE
Mogensen, P R, Grell, K, Schmiegelow, K, Overgaard, U M, Wolthers, B O, Mogensen, S S, Vaag, A & Frandsen, T L 2020, ' Dyslipidemia at diagnosis of childhood acute lymphoblastic leukemia ', PLoS ONE, vol. 15, no. 4, e0231209 . https://doi.org/10.1371/journal.pone.0231209
As survival of acute lymphoblastic leukemia (ALL) exceeds 90%, limiting therapy-related toxicity has become a key challenge. Cardio-metabolic dysfunction is a challenge during and after childhood ALL therapy. In a single center study, we measured tri