Zobrazeno 1 - 5
of 5
pro vyhledávání: '"59"'
Autor:
Leo McCluskey, Pilar Hernandez-Con, Xuemei Huang, Defne A. Amado, Michelle E. Fullard, Richard B. Dewey, Marijan Posavi, John Q. Trojanowski, Maria Diaz-Ortiz, Benjamine Liu, Daniel Weintraub, Andrew Siderowf, Jacqueline Rick, Alice Chen-Plotkin, Christine R. Swanson, R. Tyler Skrinak
Publikováno v:
PLoS Medicine, Vol 16, Iss 10, p e1002931 (2019)
PLoS Medicine
PLoS Medicine
Background Parkinson’s disease (PD) is a progressive neurodegenerative disease affecting about 5 million people worldwide with no disease-modifying therapies. We sought blood-based biomarkers in order to provide molecular characterization of indivi
Autor:
Katharina Fink, Carl Hamsten, Sahl Khalid Bedri, Anna Glaser, Ali Manouchehrinia, Jan Hillert, Tomas Olsson, Burcu Ayoglu, Hans Grönlund, Ola Nilsson, Anna Månberg, Peter Nilsson
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0217208 (2019)
PLoS ONE
PLoS ONE
Multiple sclerosis (MS) treatment options have improved significantly over the past decades, but the consequences of MS can still be devastating and the needs for monitoring treatment surveillance are considerable. In the current study we used affini
Autor:
Lei Zhu, Zhanguo Li, Rulin Jia, Xiaozhen Zhao, Y. Cheng, Yuling Chen, Cibo Huang, Xiaolin Sun, Haiteng Deng, Yuhui Li
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0199047 (2018)
PLoS ONE
PLoS ONE
Background Behcet's disease (BD) is a chronic, multisystem-involved vasculitis and its pathogenesis remains elusive. No specific serological markers for BD diagnosis have been established. Identification of novel diagnostic biomarkers will be helpful
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0170741 (2017)
PLoS ONE
PLoS ONE
Idiopathic pulmonary fibrosis (IPF) is a gradual lung disease with a survival of less than 5 years post-diagnosis for most patients. Poor molecular description of IPF has led to unsatisfactory interpretation of the pathogenesis of this disease, resul
Autor:
Richard S Finkel, Thomas O Crawford, Kathryn J Swoboda, Petra Kaufmann, Peter Juhasz, Xiaohong Li, Yu Guo, Rebecca H Li, Felicia Trachtenberg, Suzanne J Forrest, Dione T Kobayashi, Karen S Chen, Cynthia L Joyce, Thomas Plasterer, Pilot Study of Biomarkers for Spinal Muscular Atrophy Trial Group
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35462 (2012)
PLoS ONE
PLoS ONE
Background Spinal Muscular Atrophy (SMA) is a neurodegenerative motor neuron disorder resulting from a homozygous mutation of the survival of motor neuron 1 (SMN1) gene. The gene product, SMN protein, functions in RNA biosynthesis in all tissues. In