Zobrazeno 1 - 10
of 164
pro vyhledávání: '"11"'
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e62951 (2013)
PLoS ONE
PLoS ONE
BACKGROUND AND AIMS: Considering the indication of adjuvant therapy, the recurrence risk for primary gastrointestinal stromal tumor (GIST) after surgery needs to be accurately estimated. However, current risk stratification schemes may still have roo
Autor:
Rudolf Oehler, Suzann Baumann, Winfried Rebhandl, Manfred Weninger, Thomas M. Benkoe, Carlos A. Reck, Mario Pones
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 3, p e58720 (2013)
PLoS ONE, Vol 8, Iss 3, p e58720 (2013)
OBJECTIVE: A prospective study to investigate the pattern of pro- and anti-inflammatory cytokine responses in neonates with surgical necrotizing enterocolitis (NEC) and identify those cytokines being the most promising for future research. METHODS: A
Autor:
Yongzhan Nie, Shanhong Tang, Jie Liu, Kaichun Wu, Zheng Chen, Jie Ding, Guanghui Xu, Rui Fan, Lin Xia, Jiang Jin, Rui Du, Qian Bi, Liucun Gao, Shuhui Liang, Yongquan Shi, Daiming Fan
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e40169 (2012)
PLoS ONE
PLoS ONE
Background Studies have been shown that miR-125a plays an important role in carcinogenesis, however, the role of miR-125a in hepatocellular carcinoma (HCC) remains elusive. Methodology/Principal Real time-PCR (qRT-PCR) was performed to test the signi
Autor:
Laura Marín, Luis O. González, Francisco J. Vizoso, Lucía González, Salomé González-Reyes, Maria L. Lamelas, Belen Fernandez-Garcia, Noemi Eiro, José M. del Casar
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e49047 (2012)
PLoS ONE
PLoS ONE
Inflammatory conditions may promote tumor progression and aggressiveness. In previous reports, we found a group of breast cancer tumors characterized by metalloprotease-11 (MMP-11) expression by intratumoral mononuclear inflammatory cells (MICs), whi
Autor:
Hannah Breit, Benjamin Kefas, Christel Herold-Mende, Anindya Dutta, Kaitlyn Marks, Roger Abounader, Michael Synowitz, Desiree Floyd, Rainer Glass, Ying Zhang, Bijan K. Dey, Benjamin Purow
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e96239 (2014)
PLoS ONE
PLoS ONE
Glioblastoma is the most common and lethal primary brain tumor. Tumor initiation and recurrence are likely caused by a sub-population of glioblastoma stem cells, which may derive from mutated neural stem and precursor cells. Since CD133 is a stem cel
Autor:
Yang Li, Jun Li, Longgang Wei, Yingpu Tian, Wenjie Liu, Xiandong Lin, Gen-Sheng Feng, Baozhen Chen, Zhongxian Lu, Yujia Kang
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e102847 (2014)
PLoS ONE
PLoS ONE
The extranuclear estrogen receptor pathway opens up novel perspectives in many physiological and pathological processes, especially in breast carcinogenesis. However, its function and mechanisms are not fully understood. Herein we present data identi
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e91582 (2014)
PLoS ONE
PLoS ONE
Reactive oxygen species (ROS) regulate diverse cellular functions by triggering signal transduction events, such as Src and mitogen-activated protein (MAP) kinases. Here, we report the role of caveolin-1 and Src homology 2 domain-containing protein t
Autor:
Sunil K. Noothi, Subrahmanya D. Vallabhapurapu, Sang-Oh Yoon, Veena Potluri, Charles H. Lawrie, Sivakumar Vallabhapurapu, James J. Driscoll
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e66121 (2013)
PLoS ONE
PLoS ONE
Multiple Myeloma (MM) is an incurable plasma cell cancer that is caused by several chromosomal translocations and gene deletions. Although deregulation of several signaling pathways including the Nuclear Factor-Kappa B (NF-κB) pathway has been repor
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e73059 (2013)
PLoS ONE
PLoS ONE
The cells expressing the T674I point mutant of FIP1-like-1-platelet-derived growth factor receptor alpha (FIP1L1-PDGFRα) in hypereosinophilics syndrome (HES) are resistant to imatinib and some second-generation tyrosine kinase inhibitors (TKIs). The
Autor:
Christine Mauz-Körholz, Martin S. Staege, Ines Volkmer, Dieter Körholz, Katja Müller, Stefanie Kewitz, Toralf Bernig
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 2, p e89577 (2014)
PLoS ONE, Vol 9, Iss 2, p e89577 (2014)
Sequencing of individual clones from a newly established cDNA library from the chemoresistant Hodgkin's lymphoma cell line L-1236 led to the isolation of a cDNA clone corresponding to a short sequence from chromosome 1. Reverse transcriptase-polymera