Zobrazeno 101 - 110
of 700
pro vyhledávání: ''
Autor:
Sara H. Browne, George A Jones, Huan-You Wang, Xiaoying Sun, Charles C. King, Julio A. Diaz-Perez, Scott R. VandenBerg, Sonia Jain, Erin Reid, Michael Preziosi
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0170771 (2017)
PLoS ONE
PLoS ONE
Background Patients infected with HIV have a significantly increased risk of developing non–Hodgkin lymphomas despite the widespread use of HAART. To investigate mTOR pathway activity in acquired immunodeficiency syndrome (AIDS) related diffuse lar
Autor:
Chun Hao Niu, Sai Lan Liu, Wei Jing Zhang, Huan Xin Lin, Wen Wen, Li Bing Song, Liping Ye, Fang Qiu, Ling Guo, Xian Qiu Wu, Chu Yong Lin, Xiao Qing Sun
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169280 (2017)
PLoS ONE
PLoS ONE
Background Numerous studies have shown Kinesin family member 20A (KIF20A) may play a critical role in the development and progression of cancer. However, the clinical value of KIF20A in nasopharyngeal carcinoma (NPC) is unknown. Here, we investigated
Autor:
Kjetil Taskén, Helga B. Salvesen, Anne Dørum, Merete Bjørnslett, Espen Melum, Øystein Helland, Sigrid Marie Kraggerud, Line Bjørge, Ragnhild A. Lothe, Johannes Landskron, Elisabeth Wik
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0182030 (2017)
PLoS ONE
PLoS ONE
The pan lymphocyte marker CD45 exists in various isoforms arising from alternative splicing of the exons 4, 5 and 6. While naïve T cells express CD45RA translated from an mRNA containing exon 4, exons 4–6 are spliced out to encode the shorter CD45
Autor:
Natália Ferreira Scatena, Raquel M. Alves-Paiva, Barbara A. Santana, Joshua D. Podlevsky, Julian J.-L. Chen, Ana de Lourdes Candolo Martinelli, Andreza Correa Teixeira, Dhenugen Logeswaran, Flavia S. Donaires, Rodrigo T. Calado
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0183287 (2017)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
PLoS ONE
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
PLoS ONE
Telomeres are repetitive DNA sequences at linear chromosome termini, protecting chromosomes against end-to-end fusion and damage, providing chromosomal stability. Telomeres shorten with mitotic cellular division, but are maintained in cells with high
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0179366 (2017)
PLoS ONE
PLoS ONE
The relationship between human cytomegalovirus (HCMV) and glioblastoma (GBM) has been debated for more than a decade. We investigated the presence of HCMV genes, RNA and protein in GBMs and their relationships with tumor progression. Results of quant
Circulating mRNAs and miRNAs as candidate markers for the diagnosis and prognosis of prostate cancer
Autor:
Ilce Mara de Syllos Cólus, Silvia Regina Rogatto, Alexandre Rossi Paschoal, Paulo Emilio Fuganti, Mateus Camargo Barros-Filho, Hellen Kuasne, Marilesia Ferreira de Souza, Heloísa Lizotti Cilião, Fabio Albuquerque Marchi
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184094 (2017)
PLoS ONE
Souza, M F D, Kuasne, H, Barros-Filho, M D C, Cilião, H L, Marchi, F A, Fuganti, P E, Paschoal, A R, Rogatto, S R & Cólus, I M D S 2017, ' Circulating mRNAs and miRNAs as candidate markers for the diagnosis and prognosis of prostate cancer ', PLOS ONE, vol. 12, no. 9, e0184094 . https://doi.org/10.1371/journal.pone.0184094
PLoS ONE
Souza, M F D, Kuasne, H, Barros-Filho, M D C, Cilião, H L, Marchi, F A, Fuganti, P E, Paschoal, A R, Rogatto, S R & Cólus, I M D S 2017, ' Circulating mRNAs and miRNAs as candidate markers for the diagnosis and prognosis of prostate cancer ', PLOS ONE, vol. 12, no. 9, e0184094 . https://doi.org/10.1371/journal.pone.0184094
Circulating nucleic acids are found in free form in body fluids and may serve as minimally invasive tools for cancer diagnosis and prognosis. Only a few studies have investigated the potential application of circulating mRNAs and microRNAs (miRNAs) i
Autor:
Young Nyun Park, Jee San Lee, Haeryoung Kim, Jin Sub Choi, Myoung Ju Koh, Hyungjin Rhee, Kee Ho Lee, Ji Hae Nahm, Jeong Eun Yoo
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0171922 (2017)
PLoS ONE
PLOS ONE(12): 3
PLoS ONE
PLOS ONE(12): 3
Senescence secretome was recently reported to promote liver cancer in an obese mouse model. Steatohepatitic hepatocellular carcinoma (SH-HCC), a new variant of HCC, has been found in metabolic syndrome patients, and pericellular fibrosis, a character
Autor:
Mirta M. L. Sousa, Gunnar Qvigstad, Reidar Fossmark, Øystein Sørdal, Pål Vange, Berit Doseth, Helge L. Waldum, Ingunn Bakke, Arne K. Sandvik, Torunn Bruland, Vidar Beisvag
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184514 (2017)
PLoS ONE
PLoS ONE
The cytoprotective protein clusterin is often dysregulated during tumorigenesis, and in the stomach, upregulation of clusterin marks emergence of the oxyntic atrophy (loss of acid-producing parietal cells)-associated spasmolytic polypeptide-expressin
Autor:
Yan Zhuang, Shigeki Saito, Martina Korfei, Bin Shan, Fayong Luo, Andreas Guenther, Svitlana Danchuk, Joseph A. Lasky
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186615 (2017)
PLoS ONE
PLoS ONE
Background Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive and fatal disease. Histone deacetylase 6 (HDAC6) alters function and fate of various proteins via deacetylation of lysine residues, and is implicated in TGF-β1-induced EMT (epi
Autor:
Sergey I. Kutsev, Sergey V. Mordanov, Elmira P. Adilgereeva, S. A. Smirnikhina, Oksana A. Ustaeva, Oleg Shukhov, Yuriy V. Shatokhin, Ekaterina Chelysheva, Alexander Lavrov, Anna G. Turkina
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0182901 (2017)
PLoS ONE
PLoS ONE
Chronic myeloid leukemia (CML) is a myeloproliferative disease characterized by the presence of BCR/ABL fusion gene in leukemic cells, which promotes uncontrolled cell proliferation. Up to 20% of CML patients show primary resistance or non-optimal re