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Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0179366 (2017)
PLoS ONE
PLoS ONE
The relationship between human cytomegalovirus (HCMV) and glioblastoma (GBM) has been debated for more than a decade. We investigated the presence of HCMV genes, RNA and protein in GBMs and their relationships with tumor progression. Results of quant
Autor:
Eleni Lagoudaki, Eleftheria-Kleio Dermitzaki, John Souglakos, Athanasios Kotsakis, Vassilis Georgoulias, Eleni Politaki, Anastasios Koutsopoulos, Filippos Koinis, Ippokratis Messaritakis, Galatea Kallergi
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0181211 (2017)
PLoS ONE
PLoS ONE
Background To evaluate the phenotypic heterogeneity of circulating tumor cells (CTCs) based on the expression of proliferative, apoptotic and Epithelial-to-Mesenchymal Transmission (EMT) markers during front-line treatment in patients with small cell
Autor:
Jin-Sup Jung, Yun Hak Kim, Sae-Ock Oh, Dae Cheon Jeong, Myoung-Eun Han, Liangwen Liu, Ryuk-Jun Kwon, Jiyoung Kim
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171036 (2017)
PLOS ONE(12): 2
PLoS ONE
PLOS ONE(12): 2
PLoS ONE
Zinc fingers and homeoboxes (ZHX) is a transcription repressor family that contains three members; ZHX1, ZHX2, and ZHX3. Although ZHX family members have been associated with the progression of cancer, their values as prognostic factors in cancer pat
Autor:
Frank L. Heppner, Ulrich-Wilhelm Thomale, Maren Schinz, Peter Vajkoczy, Katrin Guse, Laura-Nanna Lohkamp, Arend Koch, Claire Gehlhaar
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0156422 (2016)
PLoS ONE
60th Annual Meeting of the German Society for Neuropathology and Neuroanatomy (DGNN); 20150826-20150828; Berlin; DOC15dgnnP53 /20150825/
PLoS ONE
60th Annual Meeting of the German Society for Neuropathology and Neuroanatomy (DGNN); 20150826-20150828; Berlin; DOC15dgnnP53 /20150825/
Giant Cell Glioblastoma (gcGBM) and Pleomorphic Xanthoastrocytoma (PXA) are rare astroglial tumors of the central nervous system. Although they share certain histomorphological and immunohistochemical features, they are characterized by different cli
Autor:
Rikke Fredslund Andersen, Anders Jakobsen, Torben Hansen, Anne Haahr Mellergaard Eriksen, Niels Pallisgaard, Flemming Brandt Sørensen
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0150593 (2016)
Eriksen, A H M, Andersen, R F, Pallisgaard, N, Sørensen, F B, Jakobsen, A & Hansen, T F 2016, ' MicroRNA Expression Profiling to Identify and Validate Reference Genes for the Relative Quantification of microRNA in Rectal Cancer ', P L o S One, vol. 11, no. 3, e0150593 . https://doi.org/10.1371/journal.pone.0150593
PLoS ONE
Eriksen, A H M, Andersen, R F, Pallisgaard, N, Sørensen, F B, Jakobsen, A & Hansen, T F 2016, ' MicroRNA Expression Profiling to Identify and Validate Reference Genes for the Relative Quantification of microRNA in Rectal Cancer ', P L o S One, vol. 11, no. 3, e0150593 . https://doi.org/10.1371/journal.pone.0150593
PLoS ONE
INTRODUCTION: MicroRNAs (miRNAs) play important roles in regulating biological processes at the post-transcriptional level. Deregulation of miRNAs has been observed in cancer, and miRNAs are being investigated as potential biomarkers regarding diagno
Autor:
Ju Han Kim, Mingzhao Xing, Young Jun Chai, Young A. Kim, Hyeon Gun Jee, Kyu Eun Lee, Jin Wook Yi
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159235 (2016)
PLoS ONE
PLOS ONE(11): 7
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PLOS ONE(11): 7
Background BRAF(V600E) is the most common mutation in papillary thyroid carcinoma (PTC), and it is associated with high-risk prognostic factors. However, the significance of the BRAF mRNA level in PTC remains unknown. We evaluated the significance of
Autor:
Naohiro Yonemoto, Naoto Furukawa, Hiroshi Kobayashi, Fumiki Hirahara, Yoko Ino, Hiroshi Shigetomi, Norihisa Ohtake, Etsuko Miyagi, Hisashi Hirano, Noriaki Arakawa, Yohei Miyagi, Yusuke Masuishi
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0165609 (2016)
PLoS ONE
PLoS ONE
Background There is currently no reliable serum biomarker for ovarian clear cell carcinoma (CCC), a highly lethal histological subtype of epithelial ovarian cancer (EOC). Previously, using a proteome-based approach, we identified tissue factor pathwa
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0148223 (2016)
PLoS ONE
PLoS ONE
Objectives Multidrug resistance-related protein 1 (MRP1) overexpression is a well acknowledged predictor of poor response to chemotherapy, but MRP1 also correlated to better prognosis in some reports, especially for patients not pretreated with chemo
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162502 (2016)
PLoS ONE
PLoS ONE
Objective Ezrin and p130Cas are structural proteins with an important role in signaling pathways and have been shown to promote cancer dissemination. We previously reported on overexpression of both ezrin and p130Cas in breast carcinoma effusions com
Autor:
Yun Suk Choi, Eun Sun Jang, Sook Hyang Jeong, Christian Bréchot, Jin Wook Kim, Philippe Leissner
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0151069 (2016)
PLoS ONE
PLoS ONE
Background & Aims Alpha-fetoprotein (AFP) is the most widely used serum biomarker for hepatocellular carcinoma (HCC), despite its limitations. As complementary biomarkers, protein induced by vitamin K absence (PIVKA-II), osteopontin (OPN), and Dickko