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pro vyhledávání: ''
Autor:
Jennifer Vogt, Jacqueline M. Tarrant, Priti S. Hegde, Annette T. Byrne, Monika A. Jarzabek, William R Proctor, Rajiv Raja, Jens Brodbeck, John W.M. Martens, Eric P. van der Stok, Cornelis Verhoef, Patrick Dicker, Rupal Desai, Dale Stevens, Gary Cain
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0198099 (2018)
PLoS ONE
PLoS One (online), 13(6):e0198099. Public Library of Science
PLoS ONE
PLoS One (online), 13(6):e0198099. Public Library of Science
Drug-related sinusoidal dilatation (SD) is a common form of hepatotoxicity associated with oxaliplatin-based chemotherapy used prior to resection of colorectal liver metastases (CRLM). Recently, hepatic SD has also been associated with anti-delta lik
Autor:
Fadi Brimo, Miguel M. Burnier, Ana Beatriz Toledo Dias, Shraddha Solanki, Madhuri Koti, D. Robert Siemens, Jose Joao Mansure, Alice Yu, Wassim Kassouf
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0205746 (2018)
PLoS ONE
PLoS ONE
Tumor-Infiltrating Lymphocytes (TILs) has been shown to be essential to predict disease outcome in several types of cancers. Moreover, the distribution of cytotoxic T lymphocytes (CD8+) and T cells in general (CD3+) have been used to establish an Imm
Autor:
Quentin Loyd, Liza J. Burton, Robin Roberts, Andrew Gacii, Maxine Harlemon, Nathan J. Bowen, Valerie Odero-Marah, Camille Ragin, Veronica Henderson, Ohuod Hawsawi, Simone M. Howard
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0203855 (2018)
PLoS ONE
PLoS ONE
African Americans (AA) have higher death rates due to prostate and breast cancer as compared to Caucasian Americans (CA), and few biomarkers have been associated with this disparity. In our study we investigated whether epithelial-mesenchymal transit
Autor:
Hilde Garberg, Eystein Oveland, Luiza Ghila, Magnus Berle, Simona Chera, Thomas Davidsson, Heidrun Vethe, Ole J. Halvorsen, Adeel Chaudhry, Christian Beisland, Øystein Ariansen Haaland
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0206475 (2018)
PLoS ONE
PLoS ONE
Patients with bladder cancer need frequent controls over long follow-up time due to high recurrence rate and risk of conversion to muscle invasive cancer with poor prognosis. We identified cancer-related molecular signatures in apparently healthy bla
Autor:
Aniruddh Kashyap, Rodney J. Scott, Bohdan Górski, Emilia Rogoża-Janiszewska, Cezary Cybulski, Pawel Domagala, Jan Lubinski, Bartłomiej Masojć, Romuald Maleszka, Andrzej Kram, Wojciech Kluźniak, Magdalena Kiedrowicz, Karolina Malińska, Helena Rudnicka, Jakub Deptuła, Marcin Lener, Tadeusz Dębniak, Katarzyna Paszkowska-Szczur, Dawid Murawa
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0204768 (2018)
PLoS ONE
PLoS ONE
The association of BRCA1/2 mutations with melanoma is not completely determined; the interpretation of variants of unknown significance is also problematic. To evaluate these issues we explored the molecular basis of melanoma risk by performing whole
Autor:
Chun Hao Niu, Sai Lan Liu, Wei Jing Zhang, Huan Xin Lin, Wen Wen, Li Bing Song, Liping Ye, Fang Qiu, Ling Guo, Xian Qiu Wu, Chu Yong Lin, Xiao Qing Sun
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169280 (2017)
PLoS ONE
PLoS ONE
Background Numerous studies have shown Kinesin family member 20A (KIF20A) may play a critical role in the development and progression of cancer. However, the clinical value of KIF20A in nasopharyngeal carcinoma (NPC) is unknown. Here, we investigated
Autor:
Woo Ho Kim, Young Sill Kim, Hye Sung Kim, Cheol Lee, Myung Soo Shin, Jae Wang Kim, Min Seok Cheon, Bo Gun Jang
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0174565 (2017)
PLoS ONE
PLoS ONE
Cancer-associated fibroblasts (CAFs) play important roles in cancer progression through their complex interactions with cancer cells. The secreted bone morphogenetic protein antagonist, gremlin1 (GREM1) is expressed by the CAFs of basal cell carcinom
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0187635 (2017)
PLoS ONE
PLoS ONE
Invasion and metastasis are direct causes of mortality in patients with breast cancer and require reciprocal interactions between cancer cells and the extracellular matrix (ECM). Periostin, a fasciclin-containing adhesive ECM glycoprotein, is frequen
Autor:
Donald G. Morris, Lili Deng, Elizabeth N. Kornaga, Shirin Bonni, Ayan Chanda, Emeka K. Enwere, Angela Chan
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0177639 (2017)
PLoS ONE
PLoS ONE
Metastasis is the ultimate cause of breast cancer related mortality. Epithelial-mesenchymal transition (EMT) is thought to play a crucial role in the metastatic potential of breast cancer. Growing evidence has implicated the SUMO E3 ligase PIAS1 in t
Autor:
Jin-Sup Jung, Yun Hak Kim, Sae-Ock Oh, Dae Cheon Jeong, Myoung-Eun Han, Liangwen Liu, Ryuk-Jun Kwon, Jiyoung Kim
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171036 (2017)
PLOS ONE(12): 2
PLoS ONE
PLOS ONE(12): 2
PLoS ONE
Zinc fingers and homeoboxes (ZHX) is a transcription repressor family that contains three members; ZHX1, ZHX2, and ZHX3. Although ZHX family members have been associated with the progression of cancer, their values as prognostic factors in cancer pat