Zobrazeno 1 - 10
of 50
pro vyhledávání: ''
Autor:
Wendy A. Davis, U. Fritz Bredeek, Douglas J. Ward, Andrea Mantsios, Tahilin S. Karver, Hernando Knobel, Miranda Murray, Santiago Moreno, Dolores Merino, Yogesh Punekar, Antonio Campis, Deanna Kerrigan
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0232473 (2020)
PLoS ONE
PLoS ONE
Background Two-drug regimens (2DR) to treat HIV infection have the potential to reduce long-term toxicity and increase therapeutic options for people living with HIV (PLHIV). Prior phase III trials, SWORD-1 and SWORD-2, as well as GEMINI-1 and GEMINI
Autor:
Chung Gyoo Park, Se-Young Lee, Jungmi Choi, Byoung-Gwon Kim, Eunjo Lim, Young-Seoub Hong, Min-Goo Park, Hyoun-Ju Lim, Hyoung-ho Mo, Wonseok Cha
Publikováno v:
PLoS ONE, Vol 15, Iss 8, p e0236694 (2020)
PLoS ONE
PLoS ONE
Methyl bromide (MB) is a fumigant that has been widely used for killing pests on plants in trade, soils, and structures worldwide due to its excellent permeability and insecticidal effect; however, MB should be replaced because it is an ozone-depleti
Autor:
Andrew Hodgkiss, Daisy Mak, Rajesh Kumar, Mary O'Brien, Jaishree Bhosle, R. Gunapala, D. Walder, Sanjay Popat, Anna Minchom, Nadia Yousaf
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0225509 (2019)
PLoS ONE
PLoS ONE
ObjectivesVitamin supplementation reduces pemetrexed toxicity. Raised plasma homocysteine reflects deficiency in vitamin B12 and folate, and is suppressed by supplementation. This observational study of 112 patients receiving pemetrexed-based chemoth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e046f9ea3d71181c425ae210843e43d4
http://hdl.handle.net/10044/1/76786
http://hdl.handle.net/10044/1/76786
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0253259 (2021)
PLoS ONE
PLoS ONE
Studies of the outcome of Pseudomonas aeruginosa bacteremia (Pab) have focused mainly on antibiotic appropriateness. However, P. aeruginosa possesses many virulence factors whose roles in outcomes have not been examined in humans, except for the type
Autor:
Christopher Yates, Alison M. Dines, Wojciech Waldman, Fridtjof Heyerdahl, Paul I. Dargan, Isabelle Giraudon, Piotr Kabata, David M. Wood, Knut Erik Hovda, Jacek Sein Anand
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0246297 (2021)
PLoS ONE
PLoS ONE
Background This study was conducted to retrospectively assess the relationships between: rhabdomyolysis (quantified by creatine kinase (CK) activity) and kidney injury (quantified by serum creatinine concentration), sex, age, body temperature on admi
Autor:
Dong Leilei, Wenxiu Qu, Xianfeng Wang, Xuejian Liu, Chen Cai, Zhiqing Rui, Wei Li, Xueqing Yang, Xiyuan Li
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0225307 (2019)
PLoS ONE
PLoS ONE
Aim To investigate the effect of temperature, humidity and the concentration of ambient air pollution on the hospitalization of AECOPD. Method Hospitalization record was obtained from Shenyang Medical Insurance Bureau, concluding patient’s age, gen
Autor:
Tara C. Bouton, Laura F. White, Robin M. Warren, C. Robert Horsburgh, Leonie Van Zyl, Margaretha de Vos, Karen R. Jacobson, Danie Theron, Elizabeth J. Ragan
Publikováno v:
PLoS ONE, Vol 14, Iss 10, p e0223308 (2019)
PLoS ONE
PLoS ONE
South Africa led the world with guidelines on bedaquiline (BDQ) use as a single drug substitution to manage rifampin resistant tuberculosis regimen toxicity. We examined reasons for giving BDQ in a retrospective cohort: >75% of patients were switched
Autor:
Seth M. Steinberg, Giuseppe Giaccone, Gideon M. Blumenthal, William D. Figg, Arun Rajan, Arlene Berman, Tristan M. Sissung, David J. Liewehr
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0212097 (2019)
PLoS ONE
PLoS ONE
Pharmacogenetics studies have identified several allelic variants with the potential to reduce toxicity and improve treatment outcome. The present study was designed to determine if such findings are reproducible in a heterogenous population of patie
Autor:
Ryan Vandrey, Sharon S Allen, Eric C. Donny, Neal L. Benowitz, Menglan Chen, Xianghua Luo, Jason D. Robinson, Mustafa al'Absi, Dorothy K. Hatsukami, Paul M. Cinciripini, Stephen S. Hecht, F. Joseph McClernon, Andrew A. Strasser, Rachel L Denlinger-Apte, Chap T. Le, Sharon E. Murphy, Joni Jensen, Chistopher Sipe, Steven G. Carmella
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0210104 (2019)
PLoS ONE
Chen, Menglan; Carmella, Steven G; Sipe, Chistopher; Jensen, Joni; Luo, Xianghua; Le, Chap T; et al.(2019). Longitudinal stability in cigarette smokers of urinary biomarkers of exposure to the toxicants acrylonitrile and acrolein.. PloS one, 14(1), e0210104. doi: 10.1371/journal.pone.0210104. UC Office of the President: Research Grants Program Office (RGPO). Retrieved from: http://www.escholarship.org/uc/item/2034023n
PLoS ONE
Chen, Menglan; Carmella, Steven G; Sipe, Chistopher; Jensen, Joni; Luo, Xianghua; Le, Chap T; et al.(2019). Longitudinal stability in cigarette smokers of urinary biomarkers of exposure to the toxicants acrylonitrile and acrolein.. PloS one, 14(1), e0210104. doi: 10.1371/journal.pone.0210104. UC Office of the President: Research Grants Program Office (RGPO). Retrieved from: http://www.escholarship.org/uc/item/2034023n
The urinary metabolites cyanoethyl mercapturic acid (CEMA) and 3-hydroxypropyl mercapturic acid (3-HPMA) have been widely used as biomarkers of exposure to acrylonitrile and acrolein, respectively, but there are no published data on their consistency
Autor:
Russell R. Lonser, Pierre Giglio, Rolf F. Barth, J. Bradley Elder, Vinay K. Puduvalli, Joshua L. Wang, Robert Cavaliere
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0244383 (2020)
PLoS ONE
PLoS ONE
Background Carboplatin is a potent cytoreductive agent for a variety of solid tumors. However, when delivered systemically, clinical efficacy for the treatment of high grade gliomas is poor due to limited penetration across the blood-brain barrier (B