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Autor:
Newton G. Peres, Anna B. Erazo, Meghanashree M. Shreenivas, Sven Engel, Shaun R. McColl, Sammy Bedoui, Ian Comerford, Irmgard Förster, Paul G. Whitney, Dianna M Hocking, Stephen J. McSorley, Andreas Kupz, Thomas Gebhardt, Richard A. Strugnell, Nancy Wang
Publikováno v:
PLoS Pathogens, Vol 17, Iss 10, p e1010004 (2021)
PLoS Pathogens
PLoS pathogens, vol 17, iss 10
PLoS Pathogens, Vol 17, Iss 10 (2021)
PLoS Pathogens
PLoS pathogens, vol 17, iss 10
PLoS Pathogens, Vol 17, Iss 10 (2021)
While Salmonella enterica is seen as an archetypal facultative intracellular bacterial pathogen where protection is mediated by CD4+ T cells, identifying circulating protective cells has proved very difficult, inhibiting steps to identify key antigen
Autor:
Adriana Temporão, Terry K. Smith, Rafael Luis, Miguel Prudêncio, Margarida Sanches-Vaz, Luisa M. Figueiredo, Helena Nunes-Cabaço
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 10 (2021)
PLoS Neglected Tropical Diseases, Vol 15, Iss 10, p e0009912 (2021)
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 15, Iss 10, p e0009912 (2021)
PLoS Neglected Tropical Diseases
© 2021 Temporão et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are
Autor:
Philip Hobson, Edward W. Tate, Aaron J. Borg, Lucy M. Collinson, Anja C. Schlott, Judith L. Green, Ellen Knuepfer, Catherine Maclachlan, Ambrosius P. Snijders, Abigail J. Perrin, Anthony A. Holder, Julia Morales-Sanfrutos
Publikováno v:
PLoS Biology, Vol 19, Iss 10, p e3001408 (2021)
PLoS Biology
PLoS Biology, Vol 19, Iss 10 (2021)
PLoS Biology
PLoS Biology, Vol 19, Iss 10 (2021)
We have combined chemical biology and genetic modification approaches to investigate the importance of protein myristoylation in the human malaria parasite, Plasmodium falciparum. Parasite treatment during schizogony in the last 10 to 15 hours of the
Autor:
Omar S. Akbari, Hideji Fujiwara, Damian Juncaj, Dihong Lu, Martin J. Boulanger, Susan Nguyen, Chaitra Bhat, Harpal Dhillon, Adler R. Dillman, Raghavendran Ramaswamy, Anna Buchman, Naoki Yamanaka, Shyon Nasrolahi, Sophia C. Parks
Publikováno v:
PLoS Pathogens, Vol 17, Iss 10, p e1010027 (2021)
PLoS pathogens, vol 17, iss 10
PLoS Pathogens
PLoS Pathogens, Vol 17, Iss 10 (2021)
PLoS pathogens, vol 17, iss 10
PLoS Pathogens
PLoS Pathogens, Vol 17, Iss 10 (2021)
Parasitic nematodes cause significant morbidity and mortality globally. Excretory/secretory products (ESPs) such as fatty acid- and retinol- binding proteins (FARs) are hypothesized to suppress host immunity during nematode infection, yet little is k
Autor:
Riga, Amalia, Cravo, Janine, Schmidt, Ruben, Pires, Helena R, Castiglioni, Victoria G, van den Heuvel, Sander, Boxem, Mike, Developmental Biology, Sub Developmental Biology
Publikováno v:
PLoS Genetics, Vol 17, Iss 10, p e1009856 (2021)
PLoS Genetics, 17(10), 1. Public Library of Science
PLoS Genetics
PLoS Genetics, 17(10), 1. Public Library of Science
PLoS Genetics
The conserved adapter protein Scribble (Scrib) plays essential roles in a variety of cellular processes, including polarity establishment, proliferation, and directed cell migration. While the mechanisms through which Scrib promotes epithelial polari
Autor:
Mitermayer G. Reis, Eduardo Antônio Gonçalves Ramos, Ana Amélia Nunes Santos, Federico Costa, Geórgia Virgínia da França, Fábio Neves Souza, Priscyla dos Santos Ribeiro, Cláudio Pereira Figueira, Paula Ristow
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 9, p e0009736 (2021)
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases
Rattus norvegicus (Norway rat) is the main reservoir host of pathogenic Leptospira, the causative agent of leptospirosis, in urban environments. Pathogenic Leptospira forms biofilms in the environment, possibly contributing for bacterial survival and
Autor:
Kevin Lucien, Sylvie Laumond, Marine Minier, Cameron P. Simmons, Nadège Rossi, Myrielle Dupont-Rouzeyrol, Olivia O’Connor, Nicolas Pocquet, Tristan Derycke, Frédéric Touzain, Sylvie Russet, Elodie Chalus, Heather A. Flores, David J. Hooker, Florie Cheilan, Catherine Inizan, Jordan Tutagata, Morgane Pol, Johanna M. Duyvestyn, Daniela da Silva Gonçalves, Etiene C. Pacidônio, Dominique Girault
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 9, p e0009752 (2021)
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Public Library of Science, 2021, 15 (9), pp.e0009752. ⟨10.1371/journal.pntd.0009752⟩
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Public Library of Science, 2021, 15 (9), pp.e0009752. ⟨10.1371/journal.pntd.0009752⟩
Background Biological control programs involving Wolbachia-infected Aedes aegypti are currently deployed in different epidemiological settings. New Caledonia (NC) is an ideal location for the implementation and evaluation of such a strategy as the on
Autor:
Hubertine M. E. Willems, Andrew C. Dixson, Glen E. Palmer, Junyan Liu, Stefanie Allert, Francisco N. Barrera, Brian M. Peters, Helene Tournu, Jonathan P. Richardson, Jian Miao, Christian DeJarnette, Bernhard Hube, David J. Lowes, Katherine S. Barker, Zhenbo Xu, Julian R. Naglik, Emily A. Sansevere
Publikováno v:
PLoS Pathogens, Vol 17, Iss 9, p e1009884 (2021)
PLoS Pathogens
PLoS Pathogens
Vulvovaginal candidiasis (VVC), caused primarily by the human fungal pathogen Candida albicans, results in significant quality-of-life issues for women worldwide. Candidalysin, a toxin derived from a polypeptide (Ece1p) encoded by the ECE1 gene, play
Autor:
Ingrid Alexandre de Abreu Brito, Tarcísio Fontenele de Brito, Mateus Berni, Maira Arruda Cardoso, Nicola Iovino, Attilio Pane, Fides Zenk, Vitor Lima Coelho
Publikováno v:
PLoS Pathogens, Vol 17, Iss 8, p e1009780 (2021)
PLoS Pathogens
PLoS Pathogens
Triatomine assassin bugs comprise hematophagous insect vectors of Trypanosoma cruzi, the causative agent of Chagas disease. Although the microbiome of these species has been investigated to some extent, only one virus infecting Triatoma infestans has
Single-cell RNA-sequencing reveals pre-meiotic X-chromosome dosage compensation in Drosophila testis
Publikováno v:
PLoS Genetics, Vol 17, Iss 8, p e1009728 (2021)
PLoS Genetics
PLoS Genetics
Dosage compensation equalizes X-linked expression between XY males and XX females. In male fruit flies, expression levels of the X-chromosome are increased approximately two-fold to compensate for their single X chromosome. In testis, dosage compensa