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Autor:
Holm, H, Thorsteinsdottir, U, Gretarsdottir, S, Gulcher, Jr, Thorgeirsson, G, Andersen, K, Stefansson, K, Parish, S, Bennett, Da, Clarke, R, Peto, R, Sleight, P, Collins, R, Hopewell, Jc, Watkins, H, Saleheen, D, Danesh, J, Rasheed, A, Zaidi, M, Frossard, P, Shah, N, Samuel, M, Tanaka, T, Ozaki, K, Sato, H, Sakata, Y, Komuro, I, Anand, Ss, Yusuf, S, Engert, Jc, Chambers, J, Kooner, J, Armitage, J, Samani, Nj, Braund, Ps, Nelson, Cp, Hall, As, Balmforth, A, Ball, Sg, Kleber, Me, Hoffmann, Mm, März, Wa, Bugert, P, Winkelmann, B, Böhm, Bo, Ouwehand, Wh, Sivapalaratnam, S, Kastelein, Jj, Trip, Md, Bezzina, Cr, Ouwehand, W, Yamada, Y, Elbers, Cc, Onland Moret NC, Bauer, F, van der Schouw YT, Verschuren, Wm, de Boer JM, Wijmenga, C, Hofker, Mh, de Bakker PI, Peters, Bj, Maitland van der Zee AH, de Boer, A, Klungel, Oh, Grobbee, De, Stewart, Af, Roberts, R, Mcpherson, R, Chen, L, Wells, Ga, Reilly, Mm, Li, M, Qu, I, Rader, Dj, Thorand, B, Illig, T, Peters, A, Koenig, W, Assimes, Tl, Fortmann, S, Iribarren, C, Abbate, R, Marcucci, R, Anderson, Jl, Zebrack, Js, Ardissino, D, Merlini, Fm, Bonomi, Ab, Ashfield Watt PA, Clark, Ze, van Bockxmeer FM, Brownrigg, L, Kooner, Js, Ferrer Antunes, C, Palmeiro, A, Fernandez Arcas, N, Reyes Engel, A, Folsom, Ar, Fowkes, Fg, Lee, Aj, Gaziano, Jm, Gemmati, D, Scapoli, Gl, Genest, J, Rozen, R, Girelli, Domenico, Corrocher, Roberto, Rossi, Gb, Meleady, R, Graham, Im, Gulec, S, Hopkins, Pn, Inbal, A, Selighson, U, Jukema, Jw, Litynsky, P, Kluijtmans, La, Kozich, V, Janosikova, B, Ma, J, Stampfer, Mj, Malinow, Mr, Meisel, C, Stangl, K, Morita, H, Nagai, R, Nakai, K, Nordestgaard, Bg, Zacho, J, Rimm, Eb, Schwartz, Sm, Siscovick, Ds, Silberberg, Js, Szczeklik, A, Domagala, Bt, Tanis, Bc, Rosendaal, Fm, Thogersen, Am, Nilsson, Tk, Todesco, L, Tokgozoglu, Sl, Tsai, My, Hanson, Nq, Verhoeff, Bj, Yamakawa Kobayashi, K, Hamaguchi, H.
Publikováno v:
PLoS Med. 9:e1001177 (2012)
Plos Medicine, 9
PLoS Medicine
PLoS Medicine, Vol 9, Iss 2, p e1001177 (2012)
PLoS medicine, 9(2). Public Library of Science
Plos Medicine, 9, 2
Plos Medicine, 9
PLoS Medicine
PLoS Medicine, Vol 9, Iss 2, p e1001177 (2012)
PLoS medicine, 9(2). Public Library of Science
Plos Medicine, 9, 2
Robert Clarke and colleagues conduct a meta-analysis of unpublished datasets to examine the causal relationship between elevation of homocysteine levels in the blood and the risk of coronary heart disease. Their data suggest that an increase in homoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a940120265ccb1ebb385f7aacdc7ebe0
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=7318
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=7318
Autor:
Clarke R, Bennett DA, Parish S, Verhoef P, Dötsch-Klerk M, Lathrop M, Xu P, Nordestgaard BG, Holm H, Hopewell JC, Saleheen D, Tanaka T, Anand SS, Chambers JC, Kleber ME, Ouwehand WH, Yamada Y, Elbers C, Peters B, Stewart AF
Publikováno v:
PLoS Medicine; Feb2012, Vol. 9 Issue 2, pe1001177-e1001177, 1p
Autor:
Riveros-Mckay F; Wellcome Sanger Institute, Cambridge, United Kingdom., Oliver-Williams C; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.; Homerton College, Cambridge, United Kingdom., Karthikeyan S; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom., Walter K; Wellcome Sanger Institute, Cambridge, United Kingdom., Kundu K; Wellcome Sanger Institute, Cambridge, United Kingdom.; Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge, United Kingdom., Ouwehand WH; Wellcome Sanger Institute, Cambridge, United Kingdom.; Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge, United Kingdom.; NHS Blood and Transplant, Cambridge Biomedical Campus, Cambridge, United Kingdom., Roberts D; The National Institute for Health Research Blood and Transplant Research Unit (NIHR BTRU) in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.; NHS Blood and Transplant-Oxford Centre, Level 2, John Radcliffe Hospital, Oxford, United Kingdom.; Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom., Di Angelantonio E; Wellcome Sanger Institute, Cambridge, United Kingdom.; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.; The National Institute for Health Research Blood and Transplant Research Unit (NIHR BTRU) in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, United Kingdom.; National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals, Cambridge, United Kingdom.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, United Kingdom., Soranzo N; Wellcome Sanger Institute, Cambridge, United Kingdom.; Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge, United Kingdom., Danesh J; Wellcome Sanger Institute, Cambridge, United Kingdom.; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.; The National Institute for Health Research Blood and Transplant Research Unit (NIHR BTRU) in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, United Kingdom.; National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals, Cambridge, United Kingdom.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, United Kingdom., Wheeler E; Wellcome Sanger Institute, Cambridge, United Kingdom.; MRC Epidemiology Unit, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, United Kingdom., Zeggini E; Wellcome Sanger Institute, Cambridge, United Kingdom.; Institute of Translational Genomics, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Butterworth AS; Wellcome Sanger Institute, Cambridge, United Kingdom.; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.; The National Institute for Health Research Blood and Transplant Research Unit (NIHR BTRU) in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, United Kingdom.; National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals, Cambridge, United Kingdom.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, United Kingdom., Barroso I; Wellcome Sanger Institute, Cambridge, United Kingdom.; MRC Epidemiology Unit, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, United Kingdom.
Publikováno v:
PLoS genetics [PLoS Genet] 2020 Mar 09; Vol. 16 (3), pp. e1008605. Date of Electronic Publication: 2020 Mar 09 (Print Publication: 2020).
Autor:
Zou S; Department of Cell Biology, Yale School of Medicine, New Haven, Connecticut, United States of America., Teixeira AM; Department of Pathology, Yale School of Medicine, New Haven, Connecticut, United States of America., Kostadima M; Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge, United Kingdom., Astle WJ; Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge, United Kingdom., Radhakrishnan A; Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge, United Kingdom., Simon LM; Department of Structural and Computational Biology, Baylor College of Medicine, Houston, TX, United States of America., Truman L; Department of ENT, Addenbrooke's Hospital, Cambridge Biomedical Campus, Cambridge, United Kingdom., Fang JS; Yale Cardiovascular Research Center, Department of Cardiology, Yale University School of Medicine, New Haven, CT, United States of America., Hwa J; Yale Cardiovascular Research Center, Department of Cardiology, Yale University School of Medicine, New Haven, CT, United States of America., Zhang PX; Department of Laboratory Medicine, Yale School of Medicine, New Haven, Connecticut, United States of America.; Yale Stem Cell Center, Yale School of Medicine, New Haven, Connecticut, United States of America., van der Harst P; University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, The Netherlands.; University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, The Netherlands., Bray PF; Department of Medicine and the Program in Molecular Medicine, University of Utah, Salt Lake City, Utah, United States of America., Ouwehand WH; Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge, United Kingdom., Frontini M; Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge, United Kingdom., Krause DS; Department of Cell Biology, Yale School of Medicine, New Haven, Connecticut, United States of America.; Department of Pathology, Yale School of Medicine, New Haven, Connecticut, United States of America.; Department of Laboratory Medicine, Yale School of Medicine, New Haven, Connecticut, United States of America.; Yale Stem Cell Center, Yale School of Medicine, New Haven, Connecticut, United States of America.
Publikováno v:
PloS one [PLoS One] 2017 May 23; Vol. 12 (5), pp. e0178095. Date of Electronic Publication: 2017 May 23 (Print Publication: 2017).
Autor:
Almlöf JC; Department of Medical Sciences, Molecular Medicine and Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Lundmark P; Department of Medical Sciences, Molecular Medicine and Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Lundmark A; Department of Medical Sciences, Molecular Medicine and Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Ge B; Department of Human Genetics, McGill University, Montréal, Canada., Pastinen T; Department of Human Genetics, McGill University, Montréal, Canada., Goodall AH; Department of Cardiovascular Science, University of Leicester, Leicester, United Kingdom; Leicester NIHR Biomedical Research Unit in Cardiovascular Disease, Glenfield Hospital, Leicester, United Kingdom., Cambien F; INSERM UMRS 937, Pierre and Marie Curie University and Medical School, Paris, France., Deloukas P; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, Heart Centre, Charterhouse Square London, United Kingdom; Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom; Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, Jeddah, Saudi Arabia., Ouwehand WH; Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom; National Health Service Blood and Transplant, Cambridge Centre, Long Road, Cambridge, United Kingdom., Syvänen AC; Department of Medical Sciences, Molecular Medicine and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
Publikováno v:
PloS one [PLoS One] 2014 Jul 15; Vol. 9 (7), pp. e102612. Date of Electronic Publication: 2014 Jul 15 (Print Publication: 2014).
Autor:
Bielczyk-Maczyńska E; Department of Haematology, University of Cambridge, Cambridge, United Kingdom; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom; NHS Blood and Transplant, Cambridge, United Kingdom., Serbanovic-Canic J; MRC Centre for Developmental and Biomedical Genetics, University of Sheffield, Sheffield, United Kingdom; Department of Cardiovascular Sciences, University of Sheffield, Sheffield, United Kingdom., Ferreira L; Department of Haematology, University of Cambridge, Cambridge, United Kingdom; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom., Soranzo N; Department of Haematology, University of Cambridge, Cambridge, United Kingdom; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom., Stemple DL; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom., Ouwehand WH; Department of Haematology, University of Cambridge, Cambridge, United Kingdom; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom; NHS Blood and Transplant, Cambridge, United Kingdom., Cvejic A; Department of Haematology, University of Cambridge, Cambridge, United Kingdom; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom.
Publikováno v:
PLoS genetics [PLoS Genet] 2014 Jul 10; Vol. 10 (7), pp. e1004450. Date of Electronic Publication: 2014 Jul 10 (Print Publication: 2014).
Autor:
Maiwald S; Department of Vascular Medicine, Academic Medical Centre, Amsterdam, the Netherlands; Department of Experimental Vascular Medicine, Academic Medical Centre, Amsterdam, the Netherlands., Sivapalaratnam S; Department of Vascular Medicine, Academic Medical Centre, Amsterdam, the Netherlands., Motazacker MM; Department of Experimental Vascular Medicine, Academic Medical Centre, Amsterdam, the Netherlands., van Capelleveen JC; Department of Vascular Medicine, Academic Medical Centre, Amsterdam, the Netherlands., Bot I; Division of Biopharmaceutics, Leiden/Amsterdam Centre for Drug Research, Leiden, the Netherlands; Department of Human Genetics, Wellcome Trust Sanger Institute, Hinxton, United Kingdom., de Jager SC; Division of Biopharmaceutics, Leiden/Amsterdam Centre for Drug Research, Leiden, the Netherlands; Department of Human Genetics, Wellcome Trust Sanger Institute, Hinxton, United Kingdom., van Eck M; Division of Biopharmaceutics, Leiden/Amsterdam Centre for Drug Research, Leiden, the Netherlands; Department of Human Genetics, Wellcome Trust Sanger Institute, Hinxton, United Kingdom., Jolley J; Department of Haematology, University of Cambridge, Cambridge, United Kingdom; National Health Service Blood and Transplant, Cambridge, United Kingdom., Kuiper J; Division of Biopharmaceutics, Leiden/Amsterdam Centre for Drug Research, Leiden, the Netherlands; Department of Human Genetics, Wellcome Trust Sanger Institute, Hinxton, United Kingdom., Stephens J; Department of Haematology, University of Cambridge, Cambridge, United Kingdom; National Health Service Blood and Transplant, Cambridge, United Kingdom., Albers CA; Department of Haematology, University of Cambridge, Cambridge, United Kingdom; National Health Service Blood and Transplant, Cambridge, United Kingdom., Vosmeer CR; Amsterdam Institute of Molecules, Medicines and Systems, Division of Molecular and Computational Toxicology, Department of Chemistry and Pharmaceutical Sciences, VU University, Amsterdam, the Netherlands., Kruize H; Amsterdam Institute of Molecules, Medicines and Systems, Division of Molecular and Computational Toxicology, Department of Chemistry and Pharmaceutical Sciences, VU University, Amsterdam, the Netherlands., Geerke DP; Amsterdam Institute of Molecules, Medicines and Systems, Division of Molecular and Computational Toxicology, Department of Chemistry and Pharmaceutical Sciences, VU University, Amsterdam, the Netherlands., van der Wal AC; Department of Pathology, Academic Medical Centre, Amsterdam, the Netherlands., van der Loos CM; Department of Pathology, Academic Medical Centre, Amsterdam, the Netherlands., Kastelein JJ; Department of Vascular Medicine, Academic Medical Centre, Amsterdam, the Netherlands., Trip MD; Department of Vascular Medicine, Academic Medical Centre, Amsterdam, the Netherlands., Ouwehand WH; Department of Haematology, University of Cambridge, Cambridge, United Kingdom; National Health Service Blood and Transplant, Cambridge, United Kingdom., Dallinga-Thie GM; Department of Vascular Medicine, Academic Medical Centre, Amsterdam, the Netherlands; Department of Experimental Vascular Medicine, Academic Medical Centre, Amsterdam, the Netherlands., Hovingh GK; Department of Vascular Medicine, Academic Medical Centre, Amsterdam, the Netherlands.
Publikováno v:
PloS one [PLoS One] 2014 May 30; Vol. 9 (5), pp. e98289. Date of Electronic Publication: 2014 May 30 (Print Publication: 2014).
Autor:
Ocak G; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands., Drechsler C; Department of Medicine, Division of Nephrology, University Hospital, Würzburg, Germany; Comprehensive Heart Failure Center, University of Wuerzburg, Wuerzburg, Germany; Institute of Clinical Epidemiology and Biometry, University of Wuerzburg, Wuerzburg, Germany., Vossen CY; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands., Vos HL; Department of Thrombosis and Haemostasis, Leiden University Medical Center, Leiden, The Netherlands; Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands., Rosendaal FR; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands; Department of Thrombosis and Haemostasis, Leiden University Medical Center, Leiden, The Netherlands; Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands., Reitsma PH; Department of Thrombosis and Haemostasis, Leiden University Medical Center, Leiden, The Netherlands; Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands., Hoffmann MM; Institute of Clinical Chemistry and Laboratory Medicine, University Medical Center, Freiburg, Germany., März W; Department of Public Health, Social and Preventive Medicine, University of Heidelberg, Mannheim, Germany., Ouwehand WH; Department of Hematology, University of Cambridge and National Health Service Blood and Transplant, Cambridge, United Kingdom; Department of Human Genetics, Wellcome Trust Sanger Institute, Cambridge, United Kingdom., Krediet RT; Department of Nephrology, Academic Medical Center, Amsterdam, The Netherlands., Boeschoten EW; Hans Mak Institute, Naarden, The Netherlands., Dekker FW; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands., Wanner C; Department of Medicine, Division of Nephrology, University Hospital, Würzburg, Germany; Comprehensive Heart Failure Center, University of Wuerzburg, Wuerzburg, Germany., Verduijn M; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.
Publikováno v:
PloS one [PLoS One] 2014 May 09; Vol. 9 (5), pp. e97251. Date of Electronic Publication: 2014 May 09 (Print Publication: 2014).
Autor:
Vimaleswaran KS; Centre for Paediatric Epidemiology and Biostatistics and MRC Centre of Epidemiology for Child Health, UCL Institute of Child Health, London, United Kingdom., Berry DJ, Lu C, Tikkanen E, Pilz S, Hiraki LT, Cooper JD, Dastani Z, Li R, Houston DK, Wood AR, Michaëlsson K, Vandenput L, Zgaga L, Yerges-Armstrong LM, McCarthy MI, Dupuis J, Kaakinen M, Kleber ME, Jameson K, Arden N, Raitakari O, Viikari J, Lohman KK, Ferrucci L, Melhus H, Ingelsson E, Byberg L, Lind L, Lorentzon M, Salomaa V, Campbell H, Dunlop M, Mitchell BD, Herzig KH, Pouta A, Hartikainen AL, Streeten EA, Theodoratou E, Jula A, Wareham NJ, Ohlsson C, Frayling TM, Kritchevsky SB, Spector TD, Richards JB, Lehtimäki T, Ouwehand WH, Kraft P, Cooper C, März W, Power C, Loos RJ, Wang TJ, Järvelin MR, Whittaker JC, Hingorani AD, Hyppönen E
Publikováno v:
PLoS medicine [PLoS Med] 2013; Vol. 10 (2), pp. e1001383. Date of Electronic Publication: 2013 Feb 05.
Autor:
Garnier S; INSERM, UMR_S 937, Pierre and Marie Curie University, UPMC, Paris 6, Paris, France., Truong V, Brocheton J, Zeller T, Rovital M, Wild PS, Ziegler A, Munzel T, Tiret L, Blankenberg S, Deloukas P, Erdmann J, Hengstenberg C, Samani NJ, Schunkert H, Ouwehand WH, Goodall AH, Cambien F, Trégouët DA
Publikováno v:
PLoS genetics [PLoS Genet] 2013; Vol. 9 (1), pp. e1003240. Date of Electronic Publication: 2013 Jan 31.