Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Nakanishi A"'
Autor:
Youhei Kubota, Nobuyuki Enomoto, Kenta Takaura, Hitomi Takada, Yuka Takahashi, Nobuharu Tamaki, Namiki Izumi, Mayu Higuchi, Hiroyuki Nakanishi, Mao Okada, Wann Wang, Jun Itakura, Kaoru Tsuchiya, Masayuki Kurosaki, Yasuyuki Komiyama, Yutaka Yasui
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 6, p e0198812 (2018)
PLoS ONE, Vol 13, Iss 6, p e0198812 (2018)
Background The present study aimed to investigate the impact of pre-sarcopenia on the prognosis of patients with advanced hepatocellular carcinoma (HCC) treated with sorafenib. Methods We enrolled 214 patients (71 ± 10 years old; 166 men and 48 wome
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 6, p e0198023 (2018)
PLoS ONE, Vol 13, Iss 6, p e0198023 (2018)
The freshwater crustacean Daphnia have a long history in water quality assessments and now lend themselves to detection of targeted chemicals using genetically encoded reporter gene due to recent progress in the development of genome editing tools. B
Autor:
Vay Liang W. Go, O. Joe Hines, Richard T. Waldron, Daniel W. Rosenberg, Stephen J. Pandol, Hui-Hua Chang, Enrique Rozengurt, Gang Li, Allen Mo, Aurelia Lugea, Samuel W. French, Masako Nakanishi, David W. Dawson, Guido Eibl, Hsin-Yuan Su, James Sinnett-Smith, Anna S. Gukovskaya, Aune Moro, Kazuki Takakura, Michael O. Duff
Publikováno v:
PLoS ONE
PloS one, vol 12, iss 9
PLoS ONE, Vol 12, Iss 9, p e0184455 (2017)
PloS one, vol 12, iss 9
PLoS ONE, Vol 12, Iss 9, p e0184455 (2017)
Epidemiologic data has linked obesity to a higher risk of pancreatic cancer, but the underlying mechanisms are poorly understood. To allow for detailed mechanistic studies in a relevant model mimicking diet-induced obesity and pancreatic cancer, a hi
Autor:
Shigeo Okabe, Tadatsune Iida, Tobias Opthof, Akira Yoshida, Teruki Yokoyama, Shigeru Miyagawa, Yoshiki Sawa, Issei Komuro, Haruyo Yasui, Yasushi Sakata, Keiko Miwa, Satoki Tomoyama, Jong-Kook Lee, Hiroyuki Nakanishi
Publikováno v:
PLoS ONE
PLoS ONE [E], 12(7). Public Library of Science
PLoS ONE, Vol 12, Iss 7, p e0182072 (2017)
PLoS ONE [E], 12(7). Public Library of Science
PLoS ONE, Vol 12, Iss 7, p e0182072 (2017)
Background The sympathetic nervous system is critical in maintaining the normal physiological function of the heart. Its dysfunction in pathological states may exacerbate the substrate for arrhythmias. Obviously, knowledge of its three-dimensional (3
Autor:
Keiichiro Akamatsu, Hisashige Kanbara, Hiroki Ueda, Nahomi Tokudome, Satomi Yagi, Masayuki Higuchi, Yasuhiro Koh, Kuninobu Kanai, Nobuyuki Yamamoto, Atsushi Hayata, Hiroaki Akamatsu, Masanori Nakanishi, Nakamura Seita, Katsuya Endo
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 6, p e0179744 (2017)
PLoS ONE, Vol 12, Iss 6, p e0179744 (2017)
Circulating tumor cells (CTCs), defined as tumor cells circulating in the peripheral blood of patients with solid tumors, are relatively rare. Diagnosis using CTCs is expected to help in the decision-making for precision cancer medicine. We have deve
Autor:
Masami Yamanaka, Yuri Shirane, Masanao Nakanishi, Michito Shimozuru, Toshio Tsubota, Tsuyoshi Ishinazaka, Jun Moriwaki, Takane Nose, Masakatsu Tsujino, Yasushi Masuda, Shinsuke Kasai, Fumihiko Mori
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 4, p e0176251 (2017)
PLoS ONE, Vol 12, Iss 4, p e0176251 (2017)
Knowing the reproductive characteristics of a species is essential for the appropriate conservation and management of wildlife. In this study, we investigated the demographic parameters, including age of primiparity, litter size, inter-birth interval
Autor:
Hiroyuki Nakanishi, Mao Okada, Jun Itakura, Yuka Takahashi, Namiki Izumi, Wann Oh, Mayu Higuchi, Nobuharu Tamaki, Hitomi Takada, Tomoyuki Gotou, Yasuyuki Komiyama, Yutaka Yasui, Tsuguru Hayashi, Kenta Takaura, Masayuki Kurosaki, Youhei Kubota, Nobuyuki Enomoto
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 3, p e0174649 (2017)
PLoS ONE, Vol 12, Iss 3, p e0174649 (2017)
Background Tolvaptan is vasopressin type 2 receptor antagonist that inhibits water reabsorption. It is used in combination with standard diuretics to treat ascites unresponsive to standard diuretic therapy or hyponatremia because of liver cirrhosis.
Autor:
Tomonori Inagaki, Shinichiro Yamada, Haruki Koike, Katherine Halievski, Hirotaka Nakanishi, Seiya Noda, Atsushi Hashizume, Haruhiko Banno, Akihiro Hirakawa, Cynthia L. Jordan, Gen Sobue, Yasuhiro Hijikata, Naohide Kondo, Kaori Kawai, Keisuke Suzuki, Masahisa Katsuno
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 12, p e0168846 (2016)
PLoS ONE, Vol 11, Iss 12, p e0168846 (2016)
The aim of this study was to characterize the respiratory function profile of subjects with spinal and bulbar muscular atrophy (SBMA), and to explore the underlying pathological mechanism by comparing the clinical and biochemical indices of this dise
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 10, p e0164720 (2016)
PLoS ONE, Vol 11, Iss 10, p e0164720 (2016)
Tissue-specific control of gene expression is an invaluable tool for studying various biological processes and medical applications. Efficient regulatory systems have been utilized to control transgene expression in various types of DNA viral or inte
Autor:
Takehiro Ogata, Takuya Taniguchi, Tomomi Ueyama, Naohiko Nakanishi, Daisuke Naito, Tetsuro Hamaoka, Takeru Kasahara, Kotaro Miyagawa, Naoki Maruyama, Masahiro Nishi, Satoaki Matoba
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 9, p e0162513 (2016)
PLoS ONE, Vol 11, Iss 9, p e0162513 (2016)
Mutations in the PTRF/Cavin-1 gene cause congenital generalized lipodystrophy type 4 (CGL4) associated with myopathy. Additionally, long-QT syndrome and fatal cardiac arrhythmia are observed in patients with CGL4 who have homozygous PTRF/Cavin-1 muta