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Autor:
Daniel R. Ambruso, Natalie J. Briones, Angelina F. Baroffio, John R. Murphy, Alexander D. Tran, Katherine Gowan, Bridget Sanford, Michael Ellison, Kenneth L. Jones
Publikováno v:
PLoS ONE
PLoS ONE, Vol 17, Iss 2, p e0263370 (2022)
PLoS ONE, Vol 17, Iss 2, p e0263370 (2022)
The cytokine Interferon-γ (IFN-γ) exerts powerful immunoregulatory effects on the adaptive immune system and also enhances functions of the neutrophil (PMN). The clinical use of IFN-γ has been driven by the finding that its administration to patie
Autor:
Qian Lin, Yang Liu, Simin Peng, Chunjie Liu, Tuo Lv, Liping Liao, Yinghui Li, Yanzhou Wang, Zhiyong Fan, Weiguo Wu, Jianguo Zeng, Huajiao Qiu, Xi He, Qiuzhong Dai
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 12 (2021)
PLoS ONE, Vol 16, Iss 12, p e0259896 (2021)
PLoS ONE, Vol 16, Iss 12 (2021)
PLoS ONE, Vol 16, Iss 12, p e0259896 (2021)
Magnolol is a bioactive polyphenolic compound commonly found in Magnolia officinalis. The aim of this study is to clarify the contribution of the magnolol additive on the growth performance of Linwu ducklings aging from 7 to 28 d, comparing to the ef
Autor:
Tze Chiew Christie Soo, Subha Bhassu
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 10 (2021)
PLoS ONE, Vol 16, Iss 10, p e0258655 (2021)
PLoS ONE, Vol 16, Iss 10 (2021)
PLoS ONE, Vol 16, Iss 10, p e0258655 (2021)
Diseases have remained the major issue for shrimp aquaculture industry for decades by which different shrimp species demonstrated alternative disease resistance or tolerance. However, there had been insufficient studies on the underlying host mechani
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 10, p e0258157 (2021)
PLoS ONE, Vol 16, Iss 10, p e0258157 (2021)
Eimeria parasites cause enteric disease in livestock and the closely related Cyclospora cayetanensis causes human disease. Oocysts of these coccidian parasites undergo maturation (sporulation) before becoming infectious. Here, we assessed transcripti
Autor:
Gina R. Rayat, Yulian Wu, Wenlong Huang, Kaja Matovinovic, Kunsong Chen, Xian Li, Mazzen Black, Jack H. Jhamandas, Nancy Gupta, Wen Fu, Jennifer Croden, Josue Rodrigues Silva
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 10, p e0258208 (2021)
PLoS ONE, Vol 16, Iss 10, p e0258208 (2021)
Islet transplantation is being considered as an alternative treatment for type 1 diabetes. Despite recent progress, transplant recipients continue to experience progressive loss of insulin independence. Cyanidin-3-O-Glucoside (C3G) has shown to be pr
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 10, p e0258029 (2021)
PLoS ONE, Vol 16, Iss 10, p e0258029 (2021)
Gluten-specific CD4+ T cells drive the pathogenesis of celiac disease and circulating gluten-specific T cells can be identified by staining with HLA-DQ:gluten tetramers. In this first single-cell RNA-seq study of tetramer-sorted T cells from untreate
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 9, p e0249438 (2021)
PLoS ONE, Vol 16, Iss 9, p e0249438 (2021)
Muscle derived stem cells (MDSCs) and myoblast play an important role in myotube regeneration when muscle tissue is injured. However, these cells can be induced to differentiate into adipocytes once exposed to PPARγ activator like EPA and DHA that a
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 9, p e0257908 (2021)
PLoS ONE, Vol 16, Iss 9, p e0257908 (2021)
In response to various stimuli, naïve macrophages usually polarize to M1 (classically activated) or M2 (alternatively activated) cells with distinct biological functions. Neuronal nitric oxide synthase (NOS1) is involved in M1 macrophage polarizatio
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 9, p e0256996 (2021)
PLoS ONE, Vol 16, Iss 9, p e0256996 (2021)
Dyslipidemia, atherosclerosis, and cardiovascular events can be prevented, or treated, using statins, alone or in combination with ezetimibe. The aim of the study was to compare the direct pleiotropic effects of two commonly-used statins (atorvastati
Autor:
Kamel Charaabi, Salma Fadhl, Haytham Hamden, Amor Mosbah, Meriem Msaad Guerfali, Wafa Djobbi, Ameur Cherif
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 9, p e0257097 (2021)
PLoS ONE, Vol 16, Iss 9, p e0257097 (2021)
Ceratitis capitata (medfly) is one of the most devastating crop pests worldwide. The Sterile Insect Technique (SIT) is a control method that is based on the mass rearing of males, their sterilization, and release in the field. However, the effectiven