Zobrazeno 1 - 10
of 140
pro vyhledávání: ''
Autor:
Xueqin Ni, Junrui Wang, Miao Yang, Abdul Khalique, Jiajun Li, Zhenhua Wang, Dongmei Zhang, Qihui Luo, Bo Jing, Yan Zeng, Kangcheng Pan, Dong Zeng, Wanqiang Li
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 7, p e0235476 (2020)
PLoS ONE, Vol 15, Iss 7, p e0235476 (2020)
To explore the molecular mechanism of the effect of Bacillus cereus PAS38 on the immunity of broilers, sixty 7-day-old broilers were divided into two groups with three replicates. The control group was fed with basal diet, and the treatment group was
Autor:
Chris Koceja, Ramani Ramchandran, Emily Gronseth, Ling Wang, Ankan Gupta, Suresh Kumar, Raman G. Kutty, Kevin R. Rarick
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 7, p e0235852 (2020)
PLoS ONE, Vol 15, Iss 7, p e0235852 (2020)
The medulloblastoma (MB) microenvironment is diverse, and cell-cell interactions within this milieu is of prime importance. Astrocytes, a major component of the microenvironment, have been shown to impact primary tumor cell phenotypes and metastasis.
Autor:
Mi Chen, Jun Hu, Y.B Xu, Bao Zhao, Han Zhang, Mengmeng Deng, Lijuan Qin, Yang Li, Lanlan Liu, Changfei Li, Songdong Meng, Weiwei Liu, Junwei Hou, Huaguo Zheng
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 7, p e0228302 (2020)
PLoS ONE, Vol 15, Iss 7, p e0228302 (2020)
Programmed death ligand 1 (PD-L1) has been recently shown to be a major obstacle to antiviral immunity by binding to its receptor programmed death 1 (PD-1) on specific IFN-γ producing T cells in chronic hepatitis B. Currently, IFN-α is widely used
Autor:
Tatemitsu Rai, Takahiro Iwamoto, Shinichi Uchida, Hideaki Tagashira, Koichiro Susa, Kiyoshi Isobe, Eisei Sohara, Wakana Shoda, Naohiro Nomura, Akihito Ohta, Takayasu Mori, Fumiaki Ando
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 6, p e0235360 (2020)
PLoS ONE, Vol 15, Iss 6, p e0235360 (2020)
The sodium (Na+)-chloride cotransporter (NCC) expressed in the distal convoluted tubule (DCT) is a key molecule regulating urinary Na+ and potassium (K+) excretion. We previously reported that high-K+ load rapidly dephosphorylated NCC and promoted ur
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 1, p e0227261 (2020)
PLoS ONE, Vol 15, Iss 1, p e0227261 (2020)
The epidermal growth factor receptor inhibitor cetuximab is the only oncogene-targeted agent that has been FDA approved for the treatment of head and neck squamous cell carcinoma (HNSCC). Currently, there are no biomarkers used in the clinic to predi
Autor:
Chang Han, Wenbo Ma, Kyoung-Sub Song, Jinqiang Zhang, Tong Wu, Nathan Ungerleider, Lu Yao, Weina Chen
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 1, p e0228160 (2020)
PLoS ONE, Vol 15, Iss 1, p e0228160 (2020)
Recent studies have demonstrated the implication of long noncoding RNAs (lncRNAs) in a variety of physiological and pathological processes. However, the majority of lncRNAs are functionally unknown. The current study describes that the lncRNA MALAT1
Autor:
Safia Akhtar, Helmy M. Siragy
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 12, p e0225728 (2019)
PLoS ONE, Vol 14, Iss 12, p e0225728 (2019)
Abnormal mitochondrial biogenesis and function has been linked to multiple diseases including diabetes. Recently, we demonstrated the role of renal (Pro)renin receptor (PRR) in the dysregulation of mitochondria. We hypothesized that PRR contributes t
Autor:
Min Hyeong Lee, So-Young Jung, Keum-Jin Yang, Joohyung Lee, Dohee Lee, Yoonho Kim, Dong-Kee Kim
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 12, p e0226769 (2019)
PLoS ONE, Vol 14, Iss 12, p e0226769 (2019)
The production of reactive oxygen species (ROS) by cisplatin is one of the major mechanisms of cisplatin-induced cytotoxicity. We examined the preventive effect of α-lipoic acid (LA) on cisplatin-induced toxicity via its antioxidant effects on in vi
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 11, p e0225450 (2019)
PLoS ONE, Vol 14, Iss 11, p e0225450 (2019)
Golgi reassembly and stacking protein 65 (GRASP65), which has been involved in cancer progression, is associated with tumor growth and cell apoptosis. Dihydromyricetin (DHM) has demonstrated antitumor activity in different types of human cancers. How
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 11, p e0225422 (2019)
PLoS ONE, Vol 14, Iss 11, p e0225422 (2019)
Type 2 insulin-like growth factor (IGF-II) levels are increased in fibrosing lung diseases such as idiopathic pulmonary fibrosis (IPF) and scleroderma/systemic sclerosis-associated pulmonary fibrosis (SSc). Our goal was to investigate the contributio