Zobrazeno 1 - 10
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Autor:
Daniel R. Ambruso, Natalie J. Briones, Angelina F. Baroffio, John R. Murphy, Alexander D. Tran, Katherine Gowan, Bridget Sanford, Michael Ellison, Kenneth L. Jones
Publikováno v:
PLoS ONE
PLoS ONE, Vol 17, Iss 2, p e0263370 (2022)
PLoS ONE, Vol 17, Iss 2, p e0263370 (2022)
The cytokine Interferon-γ (IFN-γ) exerts powerful immunoregulatory effects on the adaptive immune system and also enhances functions of the neutrophil (PMN). The clinical use of IFN-γ has been driven by the finding that its administration to patie
Autor:
Jamie-Lee M. Thompson, Daniel W. D. West, Thomas M. Doering, Boris P. Budiono, Sarah J. Lessard, Lauren G. Koch, Steven L. Britton, Nuala M. Byrne, Matthew A. Brown, Kevin J. Ashton, Vernon G. Coffey
Publikováno v:
PLoS ONE
PLoS ONE, Vol 17, Iss 1, p e0261723 (2022)
PLoS ONE, Vol 17, Iss 1, p e0261723 (2022)
Skeletal muscle atrophy is a physiological response to disuse, aging, and disease. We compared changes in muscle mass and the transcriptome profile after short-term immobilization in a divergent model of high and low responders to endurance training
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 12, p e0261730 (2021)
PLoS ONE, Vol 16, Iss 12, p e0261730 (2021)
In this study we investigate how β-catenin-dependent WNT signalling impacts midbrain dopaminergic neuron (mDA) specification. mDA cultures at day 65 of differentiation responded to 25 days of the tankyrase inhibitor XAV969 (XAV, 100nM) with reduced
Autor:
Yaling Hu, Shuang Liu, Dalin Sun, Wenyuan Liu, Yuxiang Liu, Ziyuan Zhang, Jingai Fang, Mingyu Zhang
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 11, p e0259436 (2021)
PLoS ONE, Vol 16, Iss 11 (2021)
PLoS ONE, Vol 16, Iss 11, p e0259436 (2021)
PLoS ONE, Vol 16, Iss 11 (2021)
Diabetic nephropathy is one of the common microvascular complications of diabetes. Iron death is a recently reported way of cell death. To explore the effects of iron death on diabetic nephropathy, iron death score of diabetic nephropathy was analyze
Autor:
Banchob Sripa, Piti Ungarreevittaya, Chadamas Sakonsinsiri, Raynoo Thanan, Chawalit Pairojkul, Prakasit Sa Ngiamwibool, Sitthichai Iamsaard, Pirawan Poosekeaw
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 11 (2021)
PLoS ONE, Vol 16, Iss 11, p e0259075 (2021)
PLoS ONE, Vol 16, Iss 11 (2021)
PLoS ONE, Vol 16, Iss 11, p e0259075 (2021)
Cholangiocarcinoma (CCA) is a group of heterogenous malignancies arising from bile duct epithelium with distinct pathological features. Adaptor proteins have implicated in cell proliferation, migration, and invasion of different cancer cells. The obj
Autor:
Nicole Polain, Wai Sin Kwong, Thomas Ratajczak, Sarah L. Rea, John P. Walsh, Carmel Cluning, Melanie A. Sultana, Jiake Xu, Nathan J. Pavlos
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 11, p e0259556 (2021)
PLoS ONE, Vol 16, Iss 11 (2021)
PLoS ONE, Vol 16, Iss 11, p e0259556 (2021)
PLoS ONE, Vol 16, Iss 11 (2021)
The LIM-domain containing protein Ajuba and the scaffold protein SQSTM1/p62 regulate signalling of NF-κB, a transcription factor involved in osteoclast differentiation and survival. The ubiquitin-associated domain of SQSTM1/p62 is frequently mutated
Autor:
Núria Capdevila, Miriam Guitart, Ariadna Ramirez-Mallafré, Xavier de la Cruz, Veronica Delgadillo, Neus Baena, Anna Ruiz, Carme Brun-Gasca, Nino Spataro, Elisabeth Gabau, Natalia Padilla, Steve Laurie, Jana Dominguez-Carral, Cinthia Aguilera, Sophia Derdak
Publikováno v:
Scientia
PLoS ONE, Vol 16, Iss 10 (2021)
PLoS ONE
PLoS ONE, Vol 16, Iss 10, p e0258766 (2021)
PLoS ONE, Vol 16, Iss 10 (2021)
PLoS ONE
PLoS ONE, Vol 16, Iss 10, p e0258766 (2021)
Síndrome de Angelman; Fenotipo Síndrome d'Angelman; Fenotip Angelman syndrome; Phenotype Angelman syndrome (AS) is a neurogenetic disorder characterized by severe developmental delay with absence of speech, happy disposition, frequent laughter, hyp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd69672710c211fe45f6d1baef45bbdc
https://hdl.handle.net/11351/7292
https://hdl.handle.net/11351/7292
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 10 (2021)
PLoS ONE, Vol 16, Iss 10, p e0259449 (2021)
PLoS ONE, Vol 16, Iss 10 (2021)
PLoS ONE, Vol 16, Iss 10, p e0259449 (2021)
Metabolic syndrome (MetS) is highly prevalent worldwide. In the United States, estimates show that more than 30% of the adult population has MetS. MetS consists of multiple phenotypes, including obesity, dyslipidemia, and impaired glucose tolerance.
Autor:
Roman A. Perez, Elia Bosch-Rué, Raquel Rodríguez-González, Leire Díez-Tercero, Begoña María Bosch-Canals
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 10 (2021)
PLoS ONE, Vol 16, Iss 10, p e0259125 (2021)
PLoS ONE, Vol 16, Iss 10 (2021)
PLoS ONE, Vol 16, Iss 10, p e0259125 (2021)
The use of copper (Cu2+) and cobalt (Co2+) has been described to stimulate blood vessel formation, a key process for the success of tissue regeneration. However, understanding how different concentrations of these ions affect cellular response is imp
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 10, p e0258157 (2021)
PLoS ONE, Vol 16, Iss 10, p e0258157 (2021)
Eimeria parasites cause enteric disease in livestock and the closely related Cyclospora cayetanensis causes human disease. Oocysts of these coccidian parasites undergo maturation (sporulation) before becoming infectious. Here, we assessed transcripti