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Autor:
Francisco M. Ortuño, Daniel Lopez-Lopez, Joaquín Dopazo, Eduardo Muñoz, Maria Peña-Chilet, Martín Garrido-Rodríguez, Marco A. Calzado
Publikováno v:
PLoS Computational Biology
Digital.CSIC. Repositorio Institucional del CSIC
instname
PLoS Computational Biology, Vol 17, Iss 2, p e1008748 (2021)
Digital.CSIC. Repositorio Institucional del CSIC
instname
PLoS Computational Biology, Vol 17, Iss 2, p e1008748 (2021)
This is a PLOS Computational Biology Software paper.
[Abstract] MIGNON is a workflow for the analysis of RNA-Seq experiments, which not only efficiently manages the estimation of gene expression levels from raw sequencing reads, but also calls g
[Abstract] MIGNON is a workflow for the analysis of RNA-Seq experiments, which not only efficiently manages the estimation of gene expression levels from raw sequencing reads, but also calls g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e41dfa344b052578c6b38e8112e02dd
https://hdl.handle.net/10668/4220
https://hdl.handle.net/10668/4220
Autor:
Feng Wenxiang, Lian Bolin, Chunmei Yu, Liu Guoyuan, Fei Zhong, Jian Zhang, Jiang Yuna, Chen Yanhong, Yu Chen
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 8, p e0236129 (2020)
PLoS ONE, Vol 15, Iss 8, p e0236129 (2020)
Salix matsudana, a member of Salicaceae, is an important ornamental tree in China. Because of its capability to tolerate high salt conditions, S. matsudana also plays an important ecological role when grown along Chinese coastal beaches, where the sa
Autor:
Sourindra Maiti, Laurence J.N. Cooper, Shan Zong, Krina K. Patel, Simon Olivares, Leo G. Flores, Amir Alpert, George McNamara, Hiroki Torikai, Tiejuan Mi
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 2, p e0228112 (2020)
PLoS ONE, Vol 15, Iss 2, p e0228112 (2020)
Neoantigens can be predicted and in some cases identified using the data obtained from the whole exome sequencing and transcriptome sequencing of tumor cells. These sequencing data can be coupled with single-cell RNA sequencing for the direct interro
Publikováno v:
PLoS ONE
PLOS ONE
PLoS ONE, Vol 15, Iss 1, p e0227882 (2020)
PLOS ONE
PLoS ONE, Vol 15, Iss 1, p e0227882 (2020)
Preterm birth is recognized as the primary cause of infant mortality worldwide. Twin pregnancies are significantly more at risk of preterm birth than singleton pregnancies. A greater understanding of why this is and better modes of treatment and prev
Autor:
Olga Ivanova, Annika Jacobsen, Jaap Heringa, Patrick Kemmeren, Philip Lijnzaad, Saman Amini, Frank C. P. Holstege, K. Anton Feenstra
Publikováno v:
PLoS Computational Biology
Amini, S, Jacobsen, A, Ivanova, O, Lijnzaad, P, Heringa, J, Holstege, F C P, Feenstra, K A & Kemmeren, P 2019, ' The ability of transcription factors to differentially regulate gene expression is a crucial component of the mechanism underlying inversion, a frequently observed genetic interaction pattern ', PLoS Computational Biology, vol. 15, no. 5, e1007061, pp. 1-27 . https://doi.org/10.1371/journal.pcbi.1007061
PLoS Computational Biology, Vol 15, Iss 5, p e1007061 (2019)
PLoS Computational Biology, 15(5):e1007061, 1-27. Public Library of Science
Amini, S, Jacobsen, A, Ivanova, O, Lijnzaad, P, Heringa, J, Holstege, F C P, Feenstra, K A & Kemmeren, P 2019, ' The ability of transcription factors to differentially regulate gene expression is a crucial component of the mechanism underlying inversion, a frequently observed genetic interaction pattern ', PLoS Computational Biology, vol. 15, no. 5, e1007061, pp. 1-27 . https://doi.org/10.1371/journal.pcbi.1007061
PLoS Computational Biology, Vol 15, Iss 5, p e1007061 (2019)
PLoS Computational Biology, 15(5):e1007061, 1-27. Public Library of Science
Genetic interactions, a phenomenon whereby combinations of mutations lead to unexpected effects, reflect how cellular processes are wired and play an important role in complex genetic diseases. Understanding the molecular basis of genetic interaction
Autor:
Jun Wan, Aaron Buechlein, Sheng Liu, Qingchun Cai, Kenneth P. Nephew, Qipeng Fan, Yan Xu, David F.B. Miller
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 6, p e0197404 (2018)
PLoS ONE, Vol 13, Iss 6, p e0197404 (2018)
The cure rate for late stage epithelial ovarian cancer (EOC) has not significantly improved over several decades. New and more effective targets and treatment modalities are urgently needed. RNA-seq analyses of a syngeneic EOC cell pair, representing
Autor:
Haiyan Yang, Shuangji Lin, Ming Sun, Yongjuan Yang, Jingxing Zhang, Tengxun Zhang, Yanhong Guo
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 11, p e0187124 (2017)
PLoS ONE, Vol 12, Iss 11, p e0187124 (2017)
Soil salinization is becoming a limitation to the utilization of ornamental plants worldwide. Crossostephium chinensis (Linnaeus) Makino is often cultivated along the southeast coast of China for its desirable ornamental qualities and high salt toler
Autor:
Jan Novak, Hong Zhang, Colin Reily, Krzysztof Kiryluk, Sindhuri Prakash, Iuliana Ionita-Laza, Robert J. Wyatt, Ali G. Gharavi, Drew Bradbury, Nikol Mladkova, Nicolas Maillard, Frank Eitner, Nan Chen, Ping Hou, François Berthoux, Yifu Li, Clara Fischman, Jürgen Floege, Jingyuan Xie, Samantha Shapiro, Robert A. LeDesma, Bruce A. Julian, Zina Moldoveanu, Hitoshi Suzuki, Thomas Rauen, Francesco Scolari
Publikováno v:
PLoS Genetics
PLoS Genetics 13(2), e1006609 (2017). doi:10.1371/journal.pgen.1006609
PLoS Genetics, Vol 13, Iss 2, p e1006609 (2017)
PLoS Genetics 13(2), e1006609 (2017). doi:10.1371/journal.pgen.1006609
PLoS Genetics, Vol 13, Iss 2, p e1006609 (2017)
Aberrant O-glycosylation of serum immunoglobulin A1 (IgA1) represents a heritable pathogenic defect in IgA nephropathy, the most common form of glomerulonephritis worldwide, but specific genetic factors involved in its determination are not known. We
Publikováno v:
PLoS Computational Biology
PLoS Computational Biology, Vol 12, Iss 10, p e1005144 (2016)
PLoS Computational Biology, Vol 12, Iss 10, p e1005144 (2016)
The recruitment of RNA-Pol-II to the transcription start site (TSS) is an important step in gene regulation in all organisms. Core promoter elements (CPE) are conserved sequence motifs that guide Pol-II to the TSS by interacting with specific transcr
Autor:
Kenneth L. Drake, Sangeeta Khare, Jairo Nunes, Carlos A. Rossetti, L. G. Adams, Robin E. Everts, Tamara Gull, Harris A. Lewin, Sara D. Lawhon, Josely F. Figueiredo
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 9, p e0161946 (2016)
PloS one, vol 11, iss 9
PLoS ONE, Vol 11, Iss 9, p e0161946 (2016)
PloS one, vol 11, iss 9
It has long been a quest in ruminants to understand how two very similar mycobacterial species, Mycobacterium avium ssp. paratuberculosis (MAP) and Mycobacterium avium ssp. avium (MAA) lead to either a chronic persistent infection or a rapid-transien