Zobrazeno 41 - 50
of 52
pro vyhledávání: ''
Autor:
Anders Svenningsson, Eva Falk, Elisabeth G. Celius, Siegrid Fuchs, Karen Schreiber, Sara Berkö, Jennifer Sun, Iris-Katharina Penner, null for the TYNERGY trial investigators
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 3, p e58643 (2013)
PLoS ONE, Vol 8, Iss 3, p e58643 (2013)
Fatigue is a significant symptom in multiple sclerosis (MS) patients. First-generation disease modifying therapies (DMTs) are at best moderately effective to improve fatigue. Observations from small cohorts have indicated that natalizumab, an antibod
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 2, p e55335 (2013)
PLoS ONE, Vol 8, Iss 2, p e55335 (2013)
OBJECTIVE: Adequate symptom control is a problem for many people with asthma. We asked whether weekly email reports on monitored use of inhaled, short-acting bronchodilators might improve scores on composite asthma-control measures. METHODS: Through
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 10, p e45303 (2012)
PLoS ONE, Vol 7, Iss 10, p e45303 (2012)
Background The purpose of this work was to determine in a clinical trial the efficacy of reducing or preventing seizures in patients with neurological handicaps through sustained cortical activation evoked by passive exposure to a specific auditory s
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 6, p e39661 (2012)
PLoS ONE, Vol 7, Iss 6, p e39661 (2012)
BackgroundPlacebo groups are used in randomised clinical trials (RCTs) to control for placebo effects, which can be large. Participants in trials can misunderstand written information particularly regarding technical aspects of trial design such as r
Autor:
Susan Buckingham, Patrick White, Marilyn Kendall, Aziz Sheikh, Hilary Pinnock, Ulugbek Nurmatov, Scott A Murray
Publikováno v:
PLoS ONE
Nurmatov, U, Buckingham, S, Kendall, M, Murray, S A, White, P, Sheikh, A & Pinnock, H 2012, ' Effectiveness of Holistic Interventions for People with Severe Chronic Obstructive Pulmonary Disease: Systematic Review of Controlled Clinical Trials ', PL o S One, vol. 7, no. 10, e46433, pp.-. https://doi.org/10.1371/journal.pone.0046433
PLoS ONE, Vol 7, Iss 10, p e46433 (2012)
Nurmatov, U, Buckingham, S, Kendall, M, Murray, S A, White, P, Sheikh, A & Pinnock, H 2012, ' Effectiveness of Holistic Interventions for People with Severe Chronic Obstructive Pulmonary Disease: Systematic Review of Controlled Clinical Trials ', PLoS ONE, vol. 7, no. 10, e46433, pp.-. https://doi.org/10.1371/journal.pone.0046433
Nurmatov, U, Buckingham, S, Kendall, M, Murray, S A, White, P, Sheikh, A & Pinnock, H 2012, ' Effectiveness of Holistic Interventions for People with Severe Chronic Obstructive Pulmonary Disease: Systematic Review of Controlled Clinical Trials ', PL o S One, vol. 7, no. 10, e46433, pp.-. https://doi.org/10.1371/journal.pone.0046433
PLoS ONE, Vol 7, Iss 10, p e46433 (2012)
Nurmatov, U, Buckingham, S, Kendall, M, Murray, S A, White, P, Sheikh, A & Pinnock, H 2012, ' Effectiveness of Holistic Interventions for People with Severe Chronic Obstructive Pulmonary Disease: Systematic Review of Controlled Clinical Trials ', PLoS ONE, vol. 7, no. 10, e46433, pp.-. https://doi.org/10.1371/journal.pone.0046433
BACKGROUND:Despite a well-recognised burden of disabling physical symptoms compounded by co-morbidities, psychological distress and social isolation, the needs of people with severe chronic obstructive pulmonary disease (COPD) are typically poorly ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dae678a06a914e86b03b226d82ccd69
Autor:
Gerd G. Gauglitz, Celeste C. Finnerty, Gabriela A. Kulp, Felicia N. Williams, Robert Kraft, Ronald P. Mlcak, Marc G. Jeschke, Oscar E. Suman, David N. Herndon
Publikováno v:
PLoS ONE
PLoS ONE, Vol 6, Iss 7, p e21245 (2011)
PLoS ONE, Vol 6, Iss 7, p e21245 (2011)
Background Main contributors to adverse outcomes in severely burned pediatric patients are profound and complex metabolic changes in response to the initial injury. It is currently unknown how long these conditions persist beyond the acute phase post
Autor:
Elizabeth A. Scoville, Paula Ponce de Leon Lovaton, Nilay Shah, Victor M. Montori, Laurie J. Pencille
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18468 (2011)
PLoS ONE
PLoS ONE
Background Despite access to effective, safe, and affordable treatment for osteoporosis, at-risk women may choose not to start bisphosphonate therapy. Understanding the reasons women give for rejecting a clinician's offer of treatment during consulta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ffb951ea37f4e76d0d786c20b9e4326
https://hdl.handle.net/20.500.12866/11087
https://hdl.handle.net/20.500.12866/11087
Autor:
Hideyuki Sawada, Tomoko Oeda, Sadako Kuno, Masahiro Nomoto, Kenji Yamamoto, Mitsutoshi Yamamoto, Kinya Hisanaga, Takashi Kawamura, Amantadine Study Group
Publikováno v:
PLoS ONE
PLoS ONE, Vol 5, Iss 12, p e15298 (2010)
PLoS ONE, Vol 5, Iss 12, p e15298 (2010)
BACKGROUND: Dyskinesias are some of the major motor complications that impair quality of life for patients with Parkinson's disease. The purpose of the present study was to investigate the efficacy of amantadine in Parkinson's disease patients suffer
Autor:
Matthew N. Davies, Nickolai Titov, Gavin Andrews, Emma Robinson, Karen Solley, Karen McIntyre
Publikováno v:
PLoS ONE
PLoS ONE, Vol 5, Iss 6, p e10939 (2010)
PLoS ONE, Vol 5, Iss 6, p e10939 (2010)
Background Internet-based cognitive behavioural therapy (iCBT) for depression is effective when guided by a clinician, less so if unguided. Question: Would guidance from a technician be as effective as guidance from a clinician? Method Randomized con
Autor:
Cheryl Carling, Elie A. Akl, Victor M. Montori, Holger J. Schünemann, Shaun Treweek, Jeph Herrin, Doris Tove Kristoffersen, Andrew D Oxman
Publikováno v:
PLoS medicine
PLoS Medicine, Vol 6, Iss 8, p e1000134 (2009)
PLoS Medicine, Vol 6, Iss 8, p e1000134 (2009)
Background While different ways of presenting treatment effects can affect health care decisions, little is known about which presentations best help people make decisions consistent with their own values. We compared six summary statistics for commu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2e981ac721a927d3176304116c37488
http://hdl.handle.net/11250/2377924
http://hdl.handle.net/11250/2377924