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Autor:
Kazuki Takada, Mototsugu Shimokawa, Shinkichi Takamori, Shinichiro Shimamatsu, Fumihiko Hirai, Yuki Ono, Tetsuzo Tagawa, Tatsuro Okamoto, Motoharu Hamatake, Isamu Okamoto, Masaki Mori
Publikováno v:
PLoS ONE
PLoS ONE, Vol 17, Iss 2, p e0263247 (2022)
PLoS ONE, Vol 17, Iss 2, p e0263247 (2022)
A recent study suggested that proton pump inhibitor (PPI) use in patients with advanced non-small-cell lung cancer (NSCLC) receiving immune checkpoint inhibitors (ICIs) was associated with poor clinical outcomes. However, the clinical impact of PPI u
Publikováno v:
PLoS ONE
Dysregulation of calcium homeostasis has been hypothesized to play a role in Alzheimer’s disease (AD) pathogenesis. Increased calcium levels can impair axonal transport, disrupt synaptic transmission, and ultimately lead to cell death. Given the po
Autor:
Karadzovska-Kotevska, Marija, Brunnström, Hans, Kosieradzki, Jaroslaw, Ek, Lars, Estberg, Christel, Staaf, Johan, Barath, Stefan, Planck, Maria
Publikováno v:
PLoS ONE
Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a minimally invasive bronchoscopic procedure, well established as a diagnostic modality of first choice for diagnosis and staging of non-small cell lung cancer (NSCLC). T
Autor:
Daniel R. Ambruso, Natalie J. Briones, Angelina F. Baroffio, John R. Murphy, Alexander D. Tran, Katherine Gowan, Bridget Sanford, Michael Ellison, Kenneth L. Jones
Publikováno v:
PLoS ONE
PLoS ONE, Vol 17, Iss 2, p e0263370 (2022)
PLoS ONE, Vol 17, Iss 2, p e0263370 (2022)
The cytokine Interferon-γ (IFN-γ) exerts powerful immunoregulatory effects on the adaptive immune system and also enhances functions of the neutrophil (PMN). The clinical use of IFN-γ has been driven by the finding that its administration to patie
Autor:
Guanghao Qin, Fang He, Hongda Zhang, Emmanuel Eric Pazo, Guangzheng Dai, Qingchi Yao, Wei He, Ling Xu, Tiezhu Lin
Publikováno v:
PLoS ONE
PLoS ONE, Vol 17, Iss 2, p e0263587 (2022)
PLoS ONE, Vol 17, Iss 2, p e0263587 (2022)
Aim To evaluate the association between the value of neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR), monocyte to high-density lipoprotein ratio (MHR) and the development of retinal artery occlusion (RAO) and retinal vein occ
Autor:
Sara B. Hernández, Sónia Castanheira, M. Graciela Pucciarelli, Juan J. Cestero, Gadea Rico-Pérez, Alberto Paradela, Juan A. Ayala, Sonsoles Velázquez, Ana San-Félix, Felipe Cava, Francisco García-del Portillo
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Biblos-e Archivo. Repositorio Institucional de la UAM
PLoS Pathogens
PLoS Pathogens, Vol 18, Iss 1, p e1010241 (2022)
instname
Biblos-e Archivo. Repositorio Institucional de la UAM
PLoS Pathogens
PLoS Pathogens, Vol 18, Iss 1, p e1010241 (2022)
Salmonella enterica causes intracellular infections that can be limited to the intestine or spread to deeper tissues. In most cases, intracellular bacteria show moderate growth. How these bacteria face host defenses that recognize peptidoglycan, is p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::926a783c26097c9cc690393d3ea8bcc6
https://hdl.handle.net/10486/700965
https://hdl.handle.net/10486/700965
Autor:
Natalia Romero Sandoval, Andrea A. Lopez Rodas, Luz Marina Llangarí, Sadiq Tariq Sadiq, Liqing Zhou, Philip J. Cooper
Publikováno v:
PLoS ONE, Vol 17, Iss 1, p e0262242 (2022)
PLoS ONE
PLoS ONE, Vol 17, Iss 1 (2022)
PLoS ONE
PLoS ONE, Vol 17, Iss 1 (2022)
Objectives To develop a simple DNA sequencing test for simultaneous identification and antimicrobial resistance (AMR) detection of multiple sexually transmitted infections (STIs). Methods Real-time PCR (qPCR) was initially performed to identify Neiss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61e28072ad65d2243cda187645c0d8be
https://openaccess.sgul.ac.uk/id/eprint/114086/1/journal.pone.0262242.pdf
https://openaccess.sgul.ac.uk/id/eprint/114086/1/journal.pone.0262242.pdf
Autor:
Boris Bogdanow, Markus Landthaler, Q.V. Phan, Lueder Wiebusch, Emanuel Wyler, Christian Hagemeier, F. Liu
Publikováno v:
PLoS Pathogens, Vol 18, Iss 1, p e1010193 (2022)
PLoS Pathogens
PLoS Pathogens
The chimpanzee cytomegalovirus (CCMV) is the closest relative of human CMV (HCMV). Because of the high conservation between these two species and the ability of human cells to fully support CCMV replication, CCMV holds great potential as a model syst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef97cc76854250bbd7b6a69159f220a0
http://edoc.mdc-berlin.de/21236/1/21236oa.pdf
http://edoc.mdc-berlin.de/21236/1/21236oa.pdf
Autor:
Pawaret Panyajai, Fah Chueahongthong, Natsima Viriyaadhammaa, Wariya Nirachonkul, Singkome Tima, Sawitree Chiampanichayakul, Songyot Anuchapreeda, Siriporn Okonogi
Publikováno v:
PLoS ONE
PLoS ONE, Vol 17, Iss 1 (2022)
PLoS ONE, Vol 17, Iss 1, p e0262335 (2022)
PLoS ONE, Vol 17, Iss 1 (2022)
PLoS ONE, Vol 17, Iss 1, p e0262335 (2022)
Zingiber ottensii, is widely used in Asian traditional remedies for the treatment of many diseases. The present study explores anticancer activity of Z. ottensii essential oil (ZOEO) and its nanoformulations. ZOEO obtained from hydrodistillation of Z
Autor:
Katie Bechman, Mark Yates, Kirsty Mann, Deepak Nagra, Laura-Jane Smith, Andy I. Rutherford, Amit Patel, Jimstan Periselneris, David Walder, Richard J. B. Dobson, Zeljko Kraljevic, James H. T. Teo, William Bernal, Richard Barker, James B. Galloway, Sam Norton
Publikováno v:
PLoS ONE
PLoS ONE, Vol 17, Iss 1, p e0261142 (2022)
PLoS ONE, Vol 17, Iss 1, p e0261142 (2022)
Background The Covid-19 pandemic in the United Kingdom has seen two waves; the first starting in March 2020 and the second in late October 2020. It is not known whether outcomes for those admitted with severe Covid were different in the first and sec