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Autor:
Kazuki Takada, Mototsugu Shimokawa, Shinkichi Takamori, Shinichiro Shimamatsu, Fumihiko Hirai, Yuki Ono, Tetsuzo Tagawa, Tatsuro Okamoto, Motoharu Hamatake, Isamu Okamoto, Masaki Mori
Publikováno v:
PLoS ONE
PLoS ONE, Vol 17, Iss 2, p e0263247 (2022)
PLoS ONE, Vol 17, Iss 2, p e0263247 (2022)
A recent study suggested that proton pump inhibitor (PPI) use in patients with advanced non-small-cell lung cancer (NSCLC) receiving immune checkpoint inhibitors (ICIs) was associated with poor clinical outcomes. However, the clinical impact of PPI u
Publikováno v:
PLoS ONE
Dysregulation of calcium homeostasis has been hypothesized to play a role in Alzheimer’s disease (AD) pathogenesis. Increased calcium levels can impair axonal transport, disrupt synaptic transmission, and ultimately lead to cell death. Given the po
Autor:
Karadzovska-Kotevska, Marija, Brunnström, Hans, Kosieradzki, Jaroslaw, Ek, Lars, Estberg, Christel, Staaf, Johan, Barath, Stefan, Planck, Maria
Publikováno v:
PLoS ONE
Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a minimally invasive bronchoscopic procedure, well established as a diagnostic modality of first choice for diagnosis and staging of non-small cell lung cancer (NSCLC). T
Autor:
Guanghao Qin, Fang He, Hongda Zhang, Emmanuel Eric Pazo, Guangzheng Dai, Qingchi Yao, Wei He, Ling Xu, Tiezhu Lin
Publikováno v:
PLoS ONE
PLoS ONE, Vol 17, Iss 2, p e0263587 (2022)
PLoS ONE, Vol 17, Iss 2, p e0263587 (2022)
Aim To evaluate the association between the value of neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR), monocyte to high-density lipoprotein ratio (MHR) and the development of retinal artery occlusion (RAO) and retinal vein occ
Autor:
Natalia Romero Sandoval, Andrea A. Lopez Rodas, Luz Marina Llangarí, Sadiq Tariq Sadiq, Liqing Zhou, Philip J. Cooper
Publikováno v:
PLoS ONE, Vol 17, Iss 1, p e0262242 (2022)
PLoS ONE
PLoS ONE, Vol 17, Iss 1 (2022)
PLoS ONE
PLoS ONE, Vol 17, Iss 1 (2022)
Objectives To develop a simple DNA sequencing test for simultaneous identification and antimicrobial resistance (AMR) detection of multiple sexually transmitted infections (STIs). Methods Real-time PCR (qPCR) was initially performed to identify Neiss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61e28072ad65d2243cda187645c0d8be
https://openaccess.sgul.ac.uk/id/eprint/114086/1/journal.pone.0262242.pdf
https://openaccess.sgul.ac.uk/id/eprint/114086/1/journal.pone.0262242.pdf
Autor:
Katie Bechman, Mark Yates, Kirsty Mann, Deepak Nagra, Laura-Jane Smith, Andy I. Rutherford, Amit Patel, Jimstan Periselneris, David Walder, Richard J. B. Dobson, Zeljko Kraljevic, James H. T. Teo, William Bernal, Richard Barker, James B. Galloway, Sam Norton
Publikováno v:
PLoS ONE
PLoS ONE, Vol 17, Iss 1, p e0261142 (2022)
PLoS ONE, Vol 17, Iss 1, p e0261142 (2022)
Background The Covid-19 pandemic in the United Kingdom has seen two waves; the first starting in March 2020 and the second in late October 2020. It is not known whether outcomes for those admitted with severe Covid were different in the first and sec
Autor:
Masanori A. Murayama, Erika Takada, Kenji Takai, Nagisa Arimitsu, Jun Shimizu, Tomoko Suzuki, Noboru Suzuki
Publikováno v:
PLoS ONE
PLoS ONE, Vol 17, Iss 1, p e0260838 (2022)
PLoS ONE, Vol 17, Iss 1, p e0260838 (2022)
The immune checkpoint molecules such as PD-L1 and PD-L2 have a substantial contribution to cancer immunotherapy including breast cancer. Microarray expression profiling identified several molecular subtypes, namely luminal-type (with a good-prognosis
Autor:
Jamie-Lee M. Thompson, Daniel W. D. West, Thomas M. Doering, Boris P. Budiono, Sarah J. Lessard, Lauren G. Koch, Steven L. Britton, Nuala M. Byrne, Matthew A. Brown, Kevin J. Ashton, Vernon G. Coffey
Publikováno v:
PLoS ONE
PLoS ONE, Vol 17, Iss 1, p e0261723 (2022)
PLoS ONE, Vol 17, Iss 1, p e0261723 (2022)
Skeletal muscle atrophy is a physiological response to disuse, aging, and disease. We compared changes in muscle mass and the transcriptome profile after short-term immobilization in a divergent model of high and low responders to endurance training
Autor:
Shoh Sasaki, Kensaku Nishihira, Atsushi Yamashita, Tomomi Fujii, Kenji Onoue, Yoshihiko Saito, Kinta Hatakeyama, Yoshisato Shibata, Yujiro Asada, Chiho Ohbayashi
Publikováno v:
PLoS ONE
PLoS ONE, Vol 17, Iss 1, p e0262413 (2022)
PLoS ONE, Vol 17, Iss 1, p e0262413 (2022)
Activation of the classical complement pathway plays a major role in regulating atherosclerosis progression, and it is believed to have both proatherogenic and atheroprotective effects. This study focused on C1q, the first protein in the classical pa
Publikováno v:
PLoS ONE
PLoS ONE, Vol 17, Iss 1 (2022)
PLoS ONE, Vol 17, Iss 1, p e0262074 (2022)
PLoS ONE, Vol 17, Iss 1 (2022)
PLoS ONE, Vol 17, Iss 1, p e0262074 (2022)
Introduction Previous studies have demonstrated that cytokines, transforming growth factor (TGF-β1), and brain-derived neurotrophic factor (BDNF) can impact the intensity of pain in rodents. However, the roles of cytokines, TGF-β1 and BDNF in human