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Autor:
Juan F. Alzate, Wildeman Zapata, María Teresa Rugeles, Natalia A. Taborda, Juan C. Hernandez, Eduardo E. Zurek, Jorge A Luján, Tulio J. Lopera, Wbeimar Aguilar-Jimenez, Miguel A. Toro
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 12, p e0260729 (2021)
PLoS ONE, Vol 16, Iss 12, p e0260729 (2021)
Intestinal microbiota facilitates food breakdown for energy metabolism and influences the immune response, maintaining mucosal homeostasis. Overall, HIV infection is associated with intestinal dysbiosis and immune activation, which has been related t
Autor:
Shubham Basu, Keith H. Baratz, Leo J. Maguire, Sanjay V. Patel, Ross A. Aleff, Michael P. Fautsch, Eric D. Wieben, Tommy A. Rinkoski
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 12, p e0260837 (2021)
PLoS ONE, Vol 16, Iss 12, p e0260837 (2021)
Expansion of CTG trinucleotide repeats (TNR) in the transcription factor 4 (TCF4) gene is highly associated with Fuchs Endothelial Corneal Dystrophy (FECD). Due to limitations in the availability of DNA from diseased corneal endothelium, sizing of CT
Autor:
Panagiota Zacharopoulou, David A. Duncan, Susanna Dunachie, Nicholas T.Y. Lim, Robert S. Paton, Craig Thompson, Ian D. Pavord, Derek C. Macallan, W J Hurt, Wentao Chen, Donal T. Skelly, P Goulder, Graham S. Ogg, Jian Luo, Wyncoll Dla., Nicholas M. Provine, Luzheng Xue, Chen Y-L., Philip Hopkins, Ali Amini, E Barnes, Matthew Edmans, Jonathan Ball, Jonathan Youngs, Anna L McNaughton, Paul Klenerman, Hannah Sharpe, Teresa Lambe, Vincent N. Miao, Oliver Sampson, Alex K. Shalek, Tihana Bicanic, Susannah Leaver
Publikováno v:
PLoS Pathogens, Vol 17, Iss 9, p e1009804 (2021)
et al. 2021, ' Identification of immune correlates of fatal outcomes in critically ill COVID-19 patients ', PLoS Pathogens, vol. 17, no. 9, e1009804 . https://doi.org/10.1371/journal.ppat.1009804
PLoS Pathogens
et al. 2021, ' Identification of immune correlates of fatal outcomes in critically ill COVID-19 patients ', PLoS Pathogens, vol. 17, no. 9, e1009804 . https://doi.org/10.1371/journal.ppat.1009804
PLoS Pathogens
Prior studies have demonstrated that immunologic dysfunction underpins severe illness in COVID-19 patients, but have lacked an in-depth analysis of the immunologic drivers of death in the most critically ill patients. We performed immunophenotyping o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4d1affc75f71fbb1aaddb6a4c83a3de
https://doi.org/10.1371/journal.ppat.1009804
https://doi.org/10.1371/journal.ppat.1009804
Autor:
Dominique Schols, Sigrid D'haese, Sofie Knoops, Fran Prenen, Sam Noppen, Emilie Pollenus, Luna Dillemans, Marion Coens, Hendrik Possemiers, Thao-Thy Pham, Blandine Franke-Fayard, Leen Vandermosten, Philippe E. Van den Steen
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 17, Iss 11, p e1010114 (2021)
PLoS Pathogens, Vol 17, Iss 11, p e1010114 (2021)
Malaria is a hazardous disease caused by Plasmodium parasites and often results in lethal complications, including malaria-associated acute respiratory distress syndrome (MA-ARDS). Parasite sequestration in the microvasculature is often observed, but
Autor:
Thomas C. Mettenleiter, Barbara G. Klupp, Herman W. Favoreel, Cliff Van Waesberghe, Jonas L. Delva
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 17, Iss 11, p e1010117 (2021)
PLOS PATHOGENS
PLoS Pathogens, Vol 17, Iss 11, p e1010117 (2021)
PLOS PATHOGENS
Plasmacytoid dendritic cells (pDC) are important innate immune cells during the onset of viral infections as they are specialized in the production of massive amounts of antiviral type I interferon (IFN). Alphaherpesviruses such as herpes simplex vir
Autor:
Mayuli Armas, Carmen Chicharro, Aroa Silgado, Tomás Pumarola, Lidia Goterris, Jordi Temprana-Salvador, Maria Ubals, Berta Ferrer, Elena Sulleiro, Adrián Sánchez-Montalvá, Gloria Aparicio, Vicenç García-Patos, Israel Molina, Núria Serre-Delcor
Publikováno v:
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 15, Iss 11, p e0009884 (2021)
PLoS Neglected Tropical Diseases, Vol 15, Iss 11 (2021)
Scientia
Repisalud
Instituto de Salud Carlos III (ISCIII)
PLoS Neglected Tropical Diseases, Vol 15, Iss 11, p e0009884 (2021)
PLoS Neglected Tropical Diseases, Vol 15, Iss 11 (2021)
Scientia
Repisalud
Instituto de Salud Carlos III (ISCIII)
Background Leishmaniasis is a neglected disease caused by different species of the protozoa Leishmania spp. Cutaneous lesions are the most common clinical manifestation. This disease is prevalent in tropical and subtropical areas, including the Medit
Autor:
Greg Saturday, Allen Grolla, Chikwe Ihekweazu, Adama Ahmad, Rebecca Rosenke, Nwando, Afolabi Akinpelu, Anders Leung, Bryce M. Warner, Dana P. Scott, Kevin Tierney, Abdulmajid S. Musa, Darwyn Kobasa, David Safronetz, Patrycja Sroga, Bryan D. Griffin, Geoff Soule, Jonathan Audet, Vinayakumar Siragam, Derek R. Stein, Alix Albietz
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 17, Iss 10, p e1009966 (2021)
PLoS Pathogens, Vol 17, Iss 10, p e1009966 (2021)
Nigeria continues to experience ever increasing annual outbreaks of Lassa fever (LF). The World Health Organization has recently declared Lassa virus (LASV) as a priority pathogen for accelerated research leading to a renewed international effort to
Autor:
Shalev Itzkovitz, Milena Rozenberg, Noam Cohen, Hassan Massalha, Keren Bahar Halpern, Adi Egozi, Shani Ben-Moshe
Publikováno v:
PLoS Biology
PLoS Biology, Vol 19, Iss 10, p e3001214 (2021)
PLoS Biology, Vol 19, Iss 10, p e3001214 (2021)
The intestine is lined with isolated lymphoid follicles (ILFs) that facilitate sampling of luminal antigens to elicit immune responses. Technical challenges related to the scarcity and small sizes of ILFs and their follicle-associated epithelium (FAE
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 9, p e0257207 (2021)
PLoS ONE, Vol 16, Iss 9, p e0257207 (2021)
Streptococcus pneumoniae (Spn) is a leading respiratory tract pathogen that colonizes the nasopharynx (NP) through adhesion to epithelial cells and immune evasion. Spn actively interacts with other microbiota in NP but the nature of these interaction
Autor:
Sheetal Verma, Mithlesh Kumari, Avinash Agarwal, Prashant Gupta, Zia Arshad, Piyush Tripathi, Ved Prakash, Suhail Sarwar Siddiqui, Vimala Venkatesh
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 9, p e0256308 (2021)
PLoS ONE, Vol 16, Iss 9, p e0256308 (2021)
Introduction Ventilator-associated pneumonia (VAP) may be a life threatening nosocomial infection encountered in intensive care units. Currently the emergence of carbapenem-resistant Gram-negative pathogens has become worrisome threat worldwide. Mate