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Autor:
Clara Dreyling, Martin Hasselmann
Publikováno v:
PLoS ONE
PLoS ONE, Vol 17, Iss 1, p e0262613 (2022)
PLoS ONE, Vol 17, Iss 1, p e0262613 (2022)
The cellular energy metabolism is one of the most conserved processes, as it is present in all living organisms. Mitochondria are providing the eukaryotic cell with energy and thus their genome and gene expression has been of broad interest for a lon
Autor:
Jamie-Lee M. Thompson, Daniel W. D. West, Thomas M. Doering, Boris P. Budiono, Sarah J. Lessard, Lauren G. Koch, Steven L. Britton, Nuala M. Byrne, Matthew A. Brown, Kevin J. Ashton, Vernon G. Coffey
Publikováno v:
PLoS ONE
PLoS ONE, Vol 17, Iss 1, p e0261723 (2022)
PLoS ONE, Vol 17, Iss 1, p e0261723 (2022)
Skeletal muscle atrophy is a physiological response to disuse, aging, and disease. We compared changes in muscle mass and the transcriptome profile after short-term immobilization in a divergent model of high and low responders to endurance training
Autor:
Blaine Harlan, Hui Gyu Park, Roman Spektor, Bethany Cummings, J. Thomas Brenna, Paul D. Soloway
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 12, p e0261783 (2021)
PLoS ONE, Vol 16, Iss 12 (2021)
PLoS ONE, Vol 16, Iss 12, p e0261783 (2021)
PLoS ONE, Vol 16, Iss 12 (2021)
Obesity promotes type 2 diabetes and cardiometabolic pathologies. Vertical sleeve gastrectomy (VSG) is used to treat obesity resulting in long-term weight loss and health improvements that precede weight loss; however, the mechanisms underlying the i
Autor:
Qian Lin, Yang Liu, Simin Peng, Chunjie Liu, Tuo Lv, Liping Liao, Yinghui Li, Yanzhou Wang, Zhiyong Fan, Weiguo Wu, Jianguo Zeng, Huajiao Qiu, Xi He, Qiuzhong Dai
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 12 (2021)
PLoS ONE, Vol 16, Iss 12, p e0259896 (2021)
PLoS ONE, Vol 16, Iss 12 (2021)
PLoS ONE, Vol 16, Iss 12, p e0259896 (2021)
Magnolol is a bioactive polyphenolic compound commonly found in Magnolia officinalis. The aim of this study is to clarify the contribution of the magnolol additive on the growth performance of Linwu ducklings aging from 7 to 28 d, comparing to the ef
Autor:
Tze Chiew Christie Soo, Subha Bhassu
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 10 (2021)
PLoS ONE, Vol 16, Iss 10, p e0258655 (2021)
PLoS ONE, Vol 16, Iss 10 (2021)
PLoS ONE, Vol 16, Iss 10, p e0258655 (2021)
Diseases have remained the major issue for shrimp aquaculture industry for decades by which different shrimp species demonstrated alternative disease resistance or tolerance. However, there had been insufficient studies on the underlying host mechani
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 10, p e0258157 (2021)
PLoS ONE, Vol 16, Iss 10, p e0258157 (2021)
Eimeria parasites cause enteric disease in livestock and the closely related Cyclospora cayetanensis causes human disease. Oocysts of these coccidian parasites undergo maturation (sporulation) before becoming infectious. Here, we assessed transcripti
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 9, p e0249438 (2021)
PLoS ONE, Vol 16, Iss 9, p e0249438 (2021)
Muscle derived stem cells (MDSCs) and myoblast play an important role in myotube regeneration when muscle tissue is injured. However, these cells can be induced to differentiate into adipocytes once exposed to PPARγ activator like EPA and DHA that a
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 9, p e0257908 (2021)
PLoS ONE, Vol 16, Iss 9, p e0257908 (2021)
In response to various stimuli, naïve macrophages usually polarize to M1 (classically activated) or M2 (alternatively activated) cells with distinct biological functions. Neuronal nitric oxide synthase (NOS1) is involved in M1 macrophage polarizatio
Autor:
Kiyoko Takane, Yoko Hikiba, Chi Zhu, Yoichi Furukawa, Kiyoshi Yamaguchi, Makoto Hirata, Shin Maeda, Tsuneo Ikenoue, Xun Liu
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 9, p e0257090 (2021)
PLoS ONE, Vol 16, Iss 9, p e0257090 (2021)
Isocitrate dehydrogenase 1 and 2 (IDH1/2) mutations and their key effector 2-hydroxyglutarate (2-HG) have been reported to promote oncogenesis in various human cancers. To elucidate molecular mechanism(s) associated with IDH1/2 mutations, we establis
Autor:
Christel Rousseaux, Paolo Spagnolo, Silvia Speca, Caroline Dubuquoy, Pierre Desreumaux, Philippe Chavatte
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 9, p e0257281 (2021)
PLoS ONE, Vol 16, Iss 9, p e0257281 (2021)
The development of more effective, better tolerated drug treatments for progressive pulmonary fibrosis (of which idiopathic pulmonary fibrosis is the most common and severe form) is a research priority. The peroxisome proliferator-activated receptor