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Autor:
Christel Rousseaux, Paolo Spagnolo, Silvia Speca, Caroline Dubuquoy, Pierre Desreumaux, Philippe Chavatte
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 9, p e0257281 (2021)
PLoS ONE, Vol 16, Iss 9, p e0257281 (2021)
The development of more effective, better tolerated drug treatments for progressive pulmonary fibrosis (of which idiopathic pulmonary fibrosis is the most common and severe form) is a research priority. The peroxisome proliferator-activated receptor
Autor:
Francis Lopes Pacagnelli, André Casanova de Oliveira, Raisa de Jesus Dutra Dias, A. C. S. Castilho, Antonio Carlos Cicogna, Thaoan Bruno Mariano, Andreo Fernando Aguiar, Ana Karênina Dias de Almeida Sabela, Sarah Santiloni Cury, Katashi Okoshi, Luis Antonio Justulin Junior, Robson Francisco Carvalho
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 9, p e0244768 (2021)
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
PLoS ONE, Vol 16, Iss 9, p e0244768 (2021)
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Made available in DSpace on 2022-04-29T08:32:48Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-09-01 Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) To gain insight on the impact of preventive exercise during pulmonary arter
Autor:
Pedro L. Silva, Lillian Moraes, Alessandra Thompson, Marcelo Gama de Abreu, Cintia L. Santos, Mariana A. Antunes, Paolo Pelosi, Cynthia S. Samary, Nazareth N. Rocha, Vera Luiza Capelozzi, Felipe Saddy, Marcos V. S. Fernandes, Soraia C. Abreu, Patricia R. M. Rocco
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 8, p e0256021 (2021)
PLoS ONE, Vol 16, Iss 8, p e0256021 (2021)
BackgroundWe hypothesized that a decrease in frequency of controlled breaths during biphasic positive airway pressure (BIVENT), associated with an increase in spontaneous breaths, whether pressure support (PSV)-assisted or not, would mitigate lung an
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 8, p e0256299 (2021)
PLoS ONE, Vol 16, Iss 8, p e0256299 (2021)
Tamoxifen is an estrogen receptor (ER) ligand with widespread use in clinical and basic research settings. Beyond its application in treating ER-positive cancer, tamoxifen has been co-opted into a powerful approach for temporal-specific genetic alter
Autor:
Joseph Grudzinski, Bryan Bednarz, Eduardo Aluicio-Sarduy, Zachary S. Morris, Karla Esbona, Elizabeth A Oseid, Mark R. Albertini, Ian Marsh, Christine Jaskowiak, Jonathan W. Engle, Kara Magee, David M. Vail, Reinier Hernandez, Paul M. Sondel, Ilene D. Kurzman, Michelle Turek, Cindy L. Zuleger, Jamey P. Weichert
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 8, p e0255798 (2021)
PLoS ONE, Vol 16, Iss 8, p e0255798 (2021)
Rationale Murine syngeneic tumor models have revealed efficacious systemic antitumor responses following primary tumor in situ vaccination combined with targeted radionuclide therapy to secondary or metastatic tumors. Here we present studies on the s
Autor:
Xavier Manière, Nicole C. McKnight, Patricia Richard, Lucie Kozlowski, Hélène Guillorit, Patrice Garnier, Antoine Danchin
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 8 (2021)
PLoS ONE, Vol 16, Iss 8, p e0253216 (2021)
PLoS ONE, Vol 16, Iss 8 (2021)
PLoS ONE, Vol 16, Iss 8, p e0253216 (2021)
Growing evidence suggests that human gut bacteria, which comprise the microbiome, are linked to several neurodegenerative disorders. An imbalance in the bacterial population in the gut of Parkinson’s disease (PD) and Alzheimer’s disease (AD) pati
Autor:
Mohan Subburaman, Bouchra Edderkaoui
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 3, p e0247913 (2021)
PLoS ONE, Vol 16, Iss 3, p e0247913 (2021)
The expression of some chemokines and chemokine receptors is induced during the development of post-traumatic osteoarthritis (PTOA), but their involvement in the pathogenesis of the disease is unclear. The goal of this study was to test whether CCL21
Autor:
Victoria Mutua, Laurel J. Gershwin, Heather A. McEligot, Francisco R. Carvallo Chaigneau, Maxim Lebedev, Paul Walsh
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 2, p e0246695 (2021)
PLoS ONE, Vol 16, Iss 2, p e0246695 (2021)
Bovine Respiratory Syncytial virus (BRSV) is one of the major infectious agents in the etiology of the bovine respiratory disease complex. BRSV causes a respiratory syndrome in calves, which is associated with severe bronchiolitis. In this study we d
Autor:
Xiaolu Zhang, Steven T. Haller, Sandrine V. Pierre, Haroon Y. Lughmani, Jiang Tian, David J. Kennedy, Xiaoming Fan, Yingnyu Gao, Joseph I. Shapiro
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 12, p e0244065 (2020)
PLoS ONE, Vol 15, Iss 12, p e0244065 (2020)
Tissue fibrosis is a significant health issue associated with organ dysfunction and failure. Increased deposition of collagen and other extracellular matrix (ECM) proteins in the interstitial area is a major process in tissue fibrosis. The microRNA-2
Autor:
Yoko Ito, Sanae Isaki, Keiko Yokoyama, Masayuki Tanaka, Koichiro Asano, Tadayuki Sato, Kana Oshinden, Chinatsu Kohno, Naokata Kutsuzawa
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 11, p e0242789 (2020)
PLoS ONE, Vol 15, Iss 11, p e0242789 (2020)
There has been an increase in the usage of heat-not-burn (HNB) cigarette products. However, their effects on alveolar epithelial cells (AECs) remain unknown. AECs are the target cells of conventional cigarette smoking-related respiratory diseases suc