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Autor:
Timon Heide, Till Braunschweig, Edgar Dahl, Janina Gasthaus, Ruth Knüchel, Janina Tiedemann, Julian Eschenbruch, Jolein Mijnes, Vera Kloten, Martin Schlensog
Publikováno v:
PLoS ONE
PLOS ONE 11(7), e0159073 (2016). doi:10.1371/journal.pone.0159073
PLoS ONE, Vol 11, Iss 7, p e0159073 (2016)
PLOS ONE 11(7), e0159073 (2016). doi:10.1371/journal.pone.0159073
PLoS ONE, Vol 11, Iss 7, p e0159073 (2016)
PLoS one 11(7), e0159073 (2016). doi:10.1371/journal.pone.0159073
Published by PLoS, Lawrence, Kan.
Published by PLoS, Lawrence, Kan.
Autor:
Eloiza H. Tajara, Sonia Maria Oliani, Luis Sérgio Raposo, Thaís Santana Gastardelo, Patrícia Maluf Cury, José Victor Maniglia, Flávia Cristina Rodrigues Lisoni, Bianca Rodrigues da Cunha
Publikováno v:
PLoS ONE
Currículo Lattes
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
PLoS ONE, Vol 9, Iss 12, p e111317 (2014)
Currículo Lattes
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
PLoS ONE, Vol 9, Iss 12, p e111317 (2014)
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Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 12, p e113928 (2014)
PLoS ONE, Vol 9, Iss 12, p e113928 (2014)
We recently found evidence that STAT1 in esophageal squamous carcinoma (ESCC) cells exerts tumor suppressor function, and it regulates five key regulators of apoptosis or cell-cycle progression, including Bcl-2, Bcl-xL, survivin, cyclin D1 and p21. I
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 4, p e95849 (2014)
PLoS ONE, Vol 9, Iss 4, p e95849 (2014)
Background Numb is an evolutionary conserved protein that plays critical roles in cell fate determination, cell adhesion, cell migration and a number of signaling pathways, but evidence for a substantial involvement of Numb in HCC has remained unclea
Autor:
Zhigang Li, Meng-Chao Wu, Haihua Qian, Chunguang Li, Hezhong Chen, Yan Yan, Changqing Su, Longlong Bao, Lei Chen, Weidan Ji
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 11, p e49693 (2012)
PLoS ONE, Vol 7, Iss 11, p e49693 (2012)
Background OCT4 and Survivin are important factors for cancer cell proliferation, renewal and dedifferentiation, and correlate with resistance to radiotherapy and chemotherapy in most human cancers, but their regulatory mechanisms are not well known.
Autor:
Karl G. Sylvester, Nadja Lehwald, Woo Sung Moon, Kyu Yun Jang, Sang Jae Noh, Ho Sung Park, Dean W. Felsher, David I. Bellovin, Guozhong Tao
Publikováno v:
PLoS ONE
PLOS ONE(7): 9
PLoS ONE, Vol 7, Iss 9, p e45119 (2012)
PLOS ONE(7): 9
PLoS ONE, Vol 7, Iss 9, p e45119 (2012)
The increased expression of SIRT1 has recently been identified in numerous human tumors and a possible correlation with c-Myc oncogene has been proposed. However, it remains unclear whether SIRT1 functions as an oncogene or tumor suppressor. We sough
Autor:
Chu Bo Qi, Leilei Chen, Kar Lok Kong, Alissa Michelle Go Wong, Sui Sui Dong, Ting Ting Cao, Li Fu, Yan Li, Jun Tian, Li Yi Zhang, Xin Yuan Guan, Juan Chen, Ming Liu, Cai Lei Zhu, Dora L.W. Kwong
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 9, p e44636 (2012)
PLoS ONE, Vol 7, Iss 9, p e44636 (2012)
Deletion of the short arm of chromosome 3 is one of the most frequent genetic alterations in many solid tumors including nasopharyngeal carcinoma (NPC), suggesting the existence of one or more tumor suppressor genes (TSGs) within the frequently delet
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 8, p e42978 (2012)
PLoS ONE, Vol 7, Iss 8, p e42978 (2012)
Background It is controversial whether microRNA-126 is a tumor suppressive or oncogenic miRNA. More experiments are needed to determine whether microRNA-126 is associated with non-small cell lung cancer risk and prognosis. Methods Over-expression of