Zobrazeno 1 - 10
of 19
pro vyhledávání: ''
Autor:
Michael F. Press, Dennis J. Slamon, Joan S. Brugge, Sara A. Hurvitz, Jason J. Zoeller, Judy Dering, Laura M. Selfors
Publikováno v:
PLoS ONE
PloS one, vol 16, iss 5
PLoS ONE, Vol 16, Iss 5, p e0251163 (2021)
PloS one, vol 16, iss 5
PLoS ONE, Vol 16, Iss 5, p e0251163 (2021)
Our previous pre-clinical work defined BCL-2 induction as a critical component of the adaptive response to lapatinib-mediated inhibition of HER2. To determine whether a similar BCL-2 upregulation occurs in lapatinib-treated patients, we evaluated gen
Autor:
Martin Götte, Sherif Abdelaziz Ibrahim, Mohamed El-Shinawi, Mona Mostafa Mohamed, Hebatallah Hassan, Ramy Gadalla, Moshira Ezzat Saleh, Ahmed M. Afifi
Publikováno v:
PLoS ONE
PLOS ONE
PubMed Central
PLoS ONE, Vol 14, Iss 5, p e0217550 (2019)
PLOS ONE
PubMed Central
PLoS ONE, Vol 14, Iss 5, p e0217550 (2019)
Herein, we aimed to identify the immunomodulatory role of tumor Syndecan-1 (CD138) in the polarization of CD4+ T helper (Th) subsets isolated from the tumor microenvironment of inflammatory breast cancer (IBC) and non-IBC patients. Lymphocytes and mo
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 5, p e0197183 (2018)
PLoS ONE, Vol 13, Iss 5, p e0197183 (2018)
Proteins belonging to the linear ubiquitin assembly complex (LUBAC) are believed to be important in tumorigenesis. LUBAC has been demonstrated to be composed of RBCK1, RNF31 and SHARPIN. The aim of this study was to explore all members of the LUBAC c
Autor:
Ivan Bièche, Didier Meseure, François Lallemand, Martine Perrot-Applanat, Marc Pocard, Sophie Vacher, Patrice Castagnet, Walid Chemlali
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 1, p e0190619 (2018)
PLoS ONE, Vol 13, Iss 1, p e0190619 (2018)
Increasing epidemiological and animal experimental data provide substantial support for the role of aryl hydrocarbon receptor (AhR) in mammary tumorigenesis. The effects of AhR have been clearly demonstrated in rodent models of breast carcinogenesis
Autor:
Grzegorz Chodaczek, Aleksandra Piotrowska, Katarzyna Nowinska, Anna Tejchman, Maciej Ugorski, Jaroslaw Suchanski, Maciej Zacharski, Piotr Dziegiel, Janusz Rys, Claudine Kieda, Jedrzej Grzegrzolka
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 9, p e0184970 (2017)
PLoS ONE, Vol 12, Iss 9, p e0184970 (2017)
In our previous studies we showed that in breast cancer podoplanin-positive cancer-associated fibroblasts correlated positively with tumor size, grade of malignancy, lymph node metastasis, lymphovascular invasion and poor patients' outcome. Therefore
Autor:
Robert L. Grossman, April Peterson, Kevin P. White, Chaitanya Bandlamudi, Vanessa Montoya, Thomas Stricker, Megan E. McNerney, Christopher D. Brown, Ralf Kittler
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 13, Iss 3, p e1006589 (2017)
PLoS Genetics, Vol 13, Iss 3, p e1006589 (2017)
Breast cancer, the second leading cause of cancer death of women worldwide, is a heterogenous disease with multiple different subtypes. These subtypes carry important implications for prognosis and therapy. Interestingly, it is known that these diffe
Autor:
Timon Heide, Till Braunschweig, Edgar Dahl, Janina Gasthaus, Ruth Knüchel, Janina Tiedemann, Julian Eschenbruch, Jolein Mijnes, Vera Kloten, Martin Schlensog
Publikováno v:
PLoS ONE
PLOS ONE 11(7), e0159073 (2016). doi:10.1371/journal.pone.0159073
PLoS ONE, Vol 11, Iss 7, p e0159073 (2016)
PLOS ONE 11(7), e0159073 (2016). doi:10.1371/journal.pone.0159073
PLoS ONE, Vol 11, Iss 7, p e0159073 (2016)
PLoS one 11(7), e0159073 (2016). doi:10.1371/journal.pone.0159073
Published by PLoS, Lawrence, Kan.
Published by PLoS, Lawrence, Kan.
Autor:
Guillermo Urrutia, Javier I. J. Orozco, Luis S. Mayorga, Angela Mathison, Maria Teresita Branham, Emanuel M. Campoy, María Roqué, Francisco E. Gago, Sergio Laurito, Raul Urrutia
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
PLoS ONE, Vol 11, Iss 7, p e0157416 (2016)
PLoS ONE
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
PLoS ONE, Vol 11, Iss 7, p e0157416 (2016)
PLoS ONE
During the last decades it has been established that breast cancer arises through the accumulation of genetic and epigenetic alterations in different cancer related genes. These alterations confer the tumor oncogenic abilities, which can be resumed a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fefdd308c27df2c540215122046b97ed
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0157416
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0157416
Autor:
Eva Carrasco, EpiGEICAM researchers, Begoña Bermejo, M. A. Jimeno, Miguel Martin, Virginia Lope, José Manuel Baena-Cañada, Silvia Antolín, Jose Ignacio Chacon, Marina Pollán, Ana Lluch, Carlos Poblete Jara, Pedro A. Sanchez, Adela Castelló, Amparo Ruiz, Ana de Juan-Ferré, Petra Rosado, Antonio Antón, Montserrat Muñoz, Elena Díaz, Ana M. Casas, Jesús Vioque, Beatriz Pérez-Gómez, Vicente Guillem, Manuel Ramos
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 5, p e0126096 (2015)
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Zaguán. Repositorio Digital de la Universidad de Zaragoza
instname
BASE-Bielefeld Academic Search Engine
Repisalud
Instituto de Salud Carlos III (ISCIII)
PLoS ONE, Vol 10, Iss 5, p e0126096 (2015)
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Zaguán. Repositorio Digital de la Universidad de Zaragoza
instname
BASE-Bielefeld Academic Search Engine
Repisalud
Instituto de Salud Carlos III (ISCIII)
BACKGROUND: According to the "World Cancer Research Fund" and the "American Institute of Cancer Research" (WCRF/AICR) one in four cancer cases could be prevented through a healthy diet, weight control and physical activity. OBJECTIVE: To explore the
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 5, p e98591 (2014)
PLoS ONE, Vol 9, Iss 5, p e98591 (2014)
Diversin was recently reported to play roles in Wnt and JNK pathways. However, the expression pattern and biological roles of diversin in human breast cancer have not been reported. In the present study, we found that diversin was overexpressed in br