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Autor:
Lara Nonell, Evelyn Andrades, Agustí Toll, Inmaculada Hernández-Muñoz, Ramon M. Pujol, Sonia Segura, Alejandra Gadea, Silvia Sánchez
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 5, p e0232146 (2020)
PLoS ONE, Vol 15, Iss 5, p e0232146 (2020)
Actinic keratosis is a common skin disease that may progress to invasive squamous cell carcinoma if left untreated. Ingenol mebutate has demonstrated efficacy in field treatment of actinic keratosis. However, molecular mechanisms on ingenol mebutate
Autor:
Raquel Pajares, María-Dolores Mendoza, Eva-Maria Andrés-Esteban, Carmen González-Vela, Laura Cereceda, Miguel A. Piris, Carlos Santonja, Heinz Kutzner, Nicolás Iglesias Pena, José P. Vaqué, Luis Requena, Angel Concha
Publikováno v:
PLoS One . 2020 Jul 20;15(7):e0232517
UCrea Repositorio Abierto de la Universidad de Cantabria
Universidad de Cantabria (UC)
PLoS ONE
PLoS ONE, Vol 15, Iss 7, p e0232517 (2020)
UCrea Repositorio Abierto de la Universidad de Cantabria
Universidad de Cantabria (UC)
PLoS ONE
PLoS ONE, Vol 15, Iss 7, p e0232517 (2020)
Aims: Merkel cell carcinoma (MCC) is an aggressive primary neuroendocrine tumor of the skin, associated with Merkel cell polyomavirus (MCPyV) in 49-89% of cases, depending on the country of origin and the techniques of detection. The presence of MCPy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c953761ed251b305e3709a7f5fc87486
http://hdl.handle.net/10902/20729
http://hdl.handle.net/10902/20729
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 5, p e0216825 (2019)
PLoS ONE, Vol 14, Iss 5, p e0216825 (2019)
Glioma is the most common type of primary brain tumor, accounting for 40% of malignant brain tumors. Although a single gene may not be a marker, an expression profiling and multivariate analyses for cancer immunotherapy must estimate survival of pati
Autor:
Jiri Hamberg, Kimmo Palin, Esa Pitkänen, Riku Katainen, Netta Mäkinen, Roosa-Maria Plaketti, Minna Taipale, Riku Laine, Ulrika A. Hänninen, Lauri A. Aaltonen, Linda M. Forsström, Jukka-Pekka Mecklin, Niko Välimäki, Ari Ristimäki, Tomas Tanskanen, Eero Pukkala
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 14, Iss 3, p e1007200 (2018)
PLoS Genetics, Vol 14, Iss 3, p e1007200 (2018)
Small bowel adenocarcinoma (SBA) is an aggressive disease with limited treatment options. Despite previous studies, its molecular genetic background has remained somewhat elusive. To comprehensively characterize the mutational landscape of this tumor
Autor:
Parviz Kokhaei, Mohammad Hojjat-Farsangi, Ali Rashidy-Pour, Ali Moshfegh, Anders Österborg, Fatemeh Pak, Lotta Hansson, Marzia Palma, Fariba Mozaffari, Håkan Mellstedt
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 2, p e0192839 (2018)
PLoS ONE, Vol 13, Iss 2, p e0192839 (2018)
Crosstalk between leukemic cells and the tumor microenvironment is of importance in chronic lymphocytic leukemia (CLL). T cells seem to sustain the survival of CLL cells by various mechanisms. The Kruppel-like family of transcription factors (KLFs) a
Autor:
Ivan Bièche, Didier Meseure, François Lallemand, Martine Perrot-Applanat, Marc Pocard, Sophie Vacher, Patrice Castagnet, Walid Chemlali
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 1, p e0190619 (2018)
PLoS ONE, Vol 13, Iss 1, p e0190619 (2018)
Increasing epidemiological and animal experimental data provide substantial support for the role of aryl hydrocarbon receptor (AhR) in mammary tumorigenesis. The effects of AhR have been clearly demonstrated in rodent models of breast carcinogenesis
Autor:
Edward F. Patz, Michael J. Campa, Alicia D. Volkheimer, J. Brice Weinberg, Eross Guadalupe, Mark T. Winkler, Ryan T. Bushey, Elizabeth B. Gottlin
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 6, p e0179841 (2017)
PLoS ONE, Vol 12, Iss 6, p e0179841 (2017)
Rituximab therapy for B cell chronic lymphocytic leukemia (B-CLL) has met with mixed success. Among several factors to which resistance can be attributed is failure to activate complement dependent cytotoxicity (CDC) due to protective complement regu
Autor:
Yang Wang, Jintang Sun, Chao Ma, Wenjuan Gao, Bingfeng Song, Hao Xue, Weiliang Chen, Xi Chen, Yun Zhang, Qianqian Shao, Qingjie Wang, Lei Zhao, Jia Liu, Xiuwen Wang, Huayang Wang, Meixiang Yang, Xun Qu
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 3, p e0152599 (2016)
PLoS ONE, Vol 11, Iss 3, p e0152599 (2016)
Galectin-9 is a widely expressed protein that is involved in immune regulation and tumorpathogenesis and serves as a marker of a poor prognosis in various types of cancers. However, the clinical impact and the precise mechanism by which this protein
Autor:
Hans Carl Hasselbalch, Torben A Kruse, Ole Weis Bjerrum, Mads Thomassen, Caroline Hasselbalch Riley, Morten K. Jensen, Lasse Kjær, Vibe Skov, Thomas Stauffer Larsen
Publikováno v:
PLoS ONE
Hasselbalch, H C, Thomassen, M, Riley, C H, Kjær, L, Larsen, T S, Jensen, M K, Bjerrum, O W, Kruse, T A & Skov, V 2014, ' Whole blood transcriptional profiling reveals deregulation of oxidative and antioxidative defence genes in myelofibrosis and related neoplasms. Potential implications of downregulation of Nrf2 for genomic instability and disease progression ', PLOS ONE, vol. 9, no. 11, e112786 . https://doi.org/10.1371/journal.pone.0112786
PLoS ONE, Vol 9, Iss 11, p e112786 (2014)
Hasselbalch, H C, Thomassen, M, Riley, C H, Kjær, L, Larsen, T S, Jensen, M K, Bjerrum, O W, Kruse, T A & Skov, V 2014, ' Whole blood transcriptional profiling reveals deregulation of oxidative and antioxidative defence genes in myelofibrosis and related neoplasms. Potential implications of downregulation of Nrf2 for genomic instability and disease progression ', PLOS ONE, vol. 9, no. 11, e112786 . https://doi.org/10.1371/journal.pone.0112786
PLoS ONE, Vol 9, Iss 11, p e112786 (2014)
The Philadelphia-negative chronic myeloproliferative neoplasms - essential thrombocythemia (ET), polycythemia vera (PV), and myelofibrosis (MF) (MPNs) - have recently been shown to be associated with chronic inflammation, oxidative stress and accumul
Autor:
Eloiza H. Tajara, Sonia Maria Oliani, Luis Sérgio Raposo, Thaís Santana Gastardelo, Patrícia Maluf Cury, José Victor Maniglia, Flávia Cristina Rodrigues Lisoni, Bianca Rodrigues da Cunha
Publikováno v:
PLoS ONE
Currículo Lattes
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
PLoS ONE, Vol 9, Iss 12, p e111317 (2014)
Currículo Lattes
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
PLoS ONE, Vol 9, Iss 12, p e111317 (2014)
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