Zobrazeno 1 - 10
of 745
pro vyhledávání: ''
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 12, p e0261730 (2021)
PLoS ONE, Vol 16, Iss 12, p e0261730 (2021)
In this study we investigate how β-catenin-dependent WNT signalling impacts midbrain dopaminergic neuron (mDA) specification. mDA cultures at day 65 of differentiation responded to 25 days of the tankyrase inhibitor XAV969 (XAV, 100nM) with reduced
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 10, p e0258726 (2021)
PLoS ONE, Vol 16, Iss 10, p e0258726 (2021)
Fusarium head blight (FHB) is an economically important disease of wheat that results in yield loss and grain contaminated with fungal mycotoxins that are harmful to human and animal health. Herein we characterised two wheat genes involved in the FHB
Autor:
Luis Martinez-Liu, Eveline Peeters, Pedro Escobar-Turriza, Mario Alberto Martínez-Núñez, Rafael Hernandez-Guerrero, Ernesto Pérez-Rueda, Nancy Rivera-Gómez
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0254025 (2021)
PLoS ONE
PLoS ONE
Archaea represent a diverse phylogenetic group that includes free-living, extremophile, mesophile, symbiont, and opportunistic organisms. These prokaryotic organisms share a high significant similarity with the basal transcriptional machinery of Euka
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4ec37d349bb0f893e4f4e576dd49310
https://biblio.vub.ac.be/vubir/comparative-genomics-of-dnabinding-transcription-factors-in-archaeal-and-bacterial-organisms(bb2b6859-d7fd-4497-9a5e-e0376ad1fcf8).html
https://biblio.vub.ac.be/vubir/comparative-genomics-of-dnabinding-transcription-factors-in-archaeal-and-bacterial-organisms(bb2b6859-d7fd-4497-9a5e-e0376ad1fcf8).html
Autor:
Jeremy L. Jenkins, Niko Beerenwinkel, Alex Gavryushkin, Ewa Szczurek, Kieran Elmes, Fabian Schmich
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 7, p e0254491 (2021)
PLoS ONE, 16 (7)
PLoS ONE, Vol 16, Iss 7, p e0254491 (2021)
PLoS ONE, 16 (7)
The treatment of complex diseases often relies on combinatorial therapy, a strategy where drugs are used to target multiple genes simultaneously. Promising candidate genes for combinatorial perturbation often constitute epistatic genes, i.e., genes w
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 7, p e0254808 (2021)
PLoS ONE, Vol 16, Iss 7, p e0254808 (2021)
MicroRNA-like small RNAs (milRNAs) and their regulatory roles in the interaction between plant and fungus have recently aroused keen interest of plant pathologists. Trichoderma spp., one of the widespread biocontrol fungi, can promote plant growth an
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 3, p e0248104 (2021)
PLoS ONE, Vol 16, Iss 3, p e0248104 (2021)
Back pain and intervertebral disc degeneration are prevalent, costly, and widely treated by manual therapies, yet the underlying causes of these diseases are indeterminate as are the scientific bases for such treatments. The present studies character
Autor:
Sari Honda, Akiko Kojima-Yuasa, Kasumi Fujita, Shigenori Kumazawa, Takumi Sonoda, Isao Matsui-Yuasa, Toshio Norikura
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 3, p e0248073 (2021)
PLoS ONE, Vol 16, Iss 3, p e0248073 (2021)
研究グループは、ココアパウダーやコーヒーパウダーの代替品としても用いられるカロブパウダー抽出物が抗肥満効果を有することを、細胞レベルおよび動物レベルで解明しました。
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 5, p e36941 (2012)
PLoS ONE, Vol 7, Iss 5, p e36941 (2012)
Our previous study shows that inhibiting activator protein one (AP1) transcription factor function in murine epidermis, using dominant-negative c-jun (TAM67), increases cell proliferation and delays differentiation. To understand the mechanism of act
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 12, p e0242773 (2020)
PLoS ONE, Vol 15, Iss 12, p e0242773 (2020)
Autism Spectrum Disorder (ASD) is a heterogeneous disorder that is often accompanied with many co-morbidities. Recent genetic studies have identified various pathways from hundreds of candidate risk genes with varying levels of association to ASD. Ho
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 12, p e0239882 (2020)
PLoS ONE, Vol 15, Iss 12, p e0239882 (2020)
Alkane-based biofuels are desirable to produce at a commercial scale as these have properties similar to current petroleum-derived transportation fuels. Rationally engineering microorganisms to produce a desirable compound, such as alkanes, is, howev