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Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 5, p e36941 (2012)
PLoS ONE, Vol 7, Iss 5, p e36941 (2012)
Our previous study shows that inhibiting activator protein one (AP1) transcription factor function in murine epidermis, using dominant-negative c-jun (TAM67), increases cell proliferation and delays differentiation. To understand the mechanism of act
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 12, p e0242773 (2020)
PLoS ONE, Vol 15, Iss 12, p e0242773 (2020)
Autism Spectrum Disorder (ASD) is a heterogeneous disorder that is often accompanied with many co-morbidities. Recent genetic studies have identified various pathways from hundreds of candidate risk genes with varying levels of association to ASD. Ho
Autor:
Liran Carmel, Fouad Zahdeh
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 12, p e0225633 (2019)
PLoS ONE, Vol 14, Iss 12, p e0225633 (2019)
The 3'-end of the coding sequence in several species is known to show specific codon usage bias. Several factors have been suggested to underlie this phenomenon, including selection against translation efficiency, selection for translation accuracy,
Autor:
Christoforos Nikolaou, Eralda Salataj, Charalampos G. Spilianakis, Chrysoula Stathopoulou, Róbert A. Hafþórsson
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 11, p e0223759 (2019)
PLoS ONE, Vol 14, Iss 11, p e0223759 (2019)
microRNAs are of vital importance for the regulation of the adaptive and innate immune responses, modulating gene expression at the post transcriptional level. Although there is cumulative information regarding the steady state mature microRNA levels
Autor:
Jianing Yang, Frederic Zenhausern, Sally A. Amundson, Alan Norquist, Carla Brooks, Jian Gu, Sanjay Mukherjee, Jerome Lacombe, Mikhail Repin, David J. Brenner
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 10, p e0222951 (2019)
PLoS ONE, Vol 14, Iss 10, p e0222951 (2019)
We report the development of system for packaging critical components of the traditional collection kit to make an integrated fingerstick blood collector for self-collecting blood samples of 100 μl or more for radiation countermeasures. A miniaturiz
Autor:
Noor Azlin Yahya, Rajan Choudhary, Malliga Raman Murali, S. Sasikumar, Saktiswaren Mohan, Hanumantha Rao Balaji Raghavendran, Tunku Kamarul, G. Krishnamurithy, Azura Mansor
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 3, p e0214212 (2019)
PLoS ONE, Vol 14, Iss 3, p e0214212 (2019)
It has been demonstrated that nanocrystalline forsterite powder synthesised using urea as a fuel in sol-gel combustion method had produced a pure forsterite (FU) and possessed superior bioactive characteristics such as bone apatite formation and anti
Autor:
Xiao Jiang, Hongmei Li, Chuhang Cheng, Chunhua Ren, Huang Wen, Xin Zhang, Yao Ruan, Ting Chen, Chaoqun Hu
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 2, p e0212887 (2019)
PLoS ONE, Vol 14, Iss 2, p e0212887 (2019)
Na+/H+ exchangers are the most common membrane proteins involved in the regulation of intracellular pH that concurrently transport Na+ into the cells and H+ out of the cells. In this study, the full-length cDNA of the Na+/H+ exchanger (NHE) from the
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 1, p e0203566 (2019)
PLoS ONE, Vol 14, Iss 1, p e0203566 (2019)
Internal RNA modifications have been known for decades, however their roles in mRNA regulation have only recently started to be elucidated. Here we investigated the most abundant mRNA modification, N6-methyladenosine (m6A) in transcripts from the hip
Autor:
Martha Bibbins-Martínez, Agustín López-Munguía, Miguel Angel Villalobos-López, J. Cuamatzi-Flores, Analilia Arroyo-Becerra, Soley Nava-Galicia, E. Esquivel-Naranjo
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 1, p e0209711 (2019)
PLoS ONE, Vol 14, Iss 1, p e0209711 (2019)
Dye-decolorizing peroxidase (DyP) from the white rot basidiomycete Pleurotus ostreatus is a heme peroxidase able to oxidize diverse substrates, including recalcitrant phenols and dyes. This study analyzed the effect of chemical dyes on P. ostreatus g
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 11, p e0207027 (2018)
PLoS ONE, Vol 13, Iss 11, p e0207027 (2018)
Opioids are widely used for treating different types of pains, but overuse and abuse of prescription opioids have led to opioid epidemic in the United States. Besides analgesic effects, chronic use of opioid can also cause tolerance, dependence, and